Publications by authors named "Neil Wedlock"

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subsp. antigens induce cellular immune responses in cattle without causing reactivity to tuberculin in the tuberculosis skin test.
Sandeep K Gupta, Tania Wilson, Paul H Maclean, Bernd H A Rehm, Axel Heiser, D Neil Wedlock

Front Immunol· February 2023

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The trehalose glycolipid C18Brar promotes antibody and T-cell immune responses to Mannheimia haemolytica and Mycoplasma ovipneumoniae whole cell antigens in sheep.
Sandeep K Gupta, Natalie Parlane, Benjamin Bridgeman, Amy T Lynch, Emma M Dangerfield, D Neil Wedlock

PLoS One· January 2023

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Cross-reactivity of antibodies to different rumen methanogens demonstrated using immunomagnetic capture technology.
Sofia Khanum, Joanna M Roberts, Rosemary W Heathcott, Stefanie Bagley, Tania Wilson, D Neil Wedlock

Front Microbiol· August 2022

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Test performance data demonstrates utility of a cattle DIVA skin test reagent (DST-F) compatible with BCG vaccination.
Gareth J Jones, Timm Konold, Shellene Hurley, Tom Holder, Sabine Steinbach, D Neil Wedlock

Sci Rep· July 2022

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Mapping immunogenic epitopes of an adhesin-like protein from Methanobrevibacter ruminantium M1 and comparison of empirical data with in silico prediction methods.
Sofia Khanum, Vincenzo Carbone, Sandeep K Gupta, Juliana Yeung, Dairu Shu, D Neil Wedlock

Sci Rep· June 2022

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Recombinase polymerase amplification assay combined with a dipstick-readout for rapid detection of Mycoplasma ovipneumoniae infections.
Sandeep K Gupta, Qing Deng, Tanushree B Gupta, Paul Maclean, Joerg Jores, D Neil Wedlock

PLoS One· August 2021

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Trehalose diamide glycolipids augment antigen-specific antibody responses in a Mincle-dependent manner.
Amy T Lynch, Chihiro Motozono, Amy J Foster, Kristel Kodar, Emma M Dangerfield, D Neil Wedlock

Bioorg Chem· May 2021

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Self-assembled particulate vaccine elicits strong immune responses and reduces Mycobacterium avium subsp. paratuberculosis infection in mice.
Sandeep K Gupta, Natalie A Parlane, Dongwen Luo, Bernd H A Rehm, Axel Heiser, D Neil Wedlock

Sci Rep· December 2020

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Heterologous peptide display on chromatin nanofibers: A new strategy for peptide vaccines.
Natalie A Parlane, D Neil Wedlock, Jun-Hee Han, Jeong Hyeon Park

Biochem Biophys Res Commun· April 2020

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Detection of microRNA in cattle serum and their potential use to diagnose severity of Johne's disease.
Sandeep K Gupta, Paul H Maclean, Siva Ganesh, Dairu Shu, Bryce M Buddle, D Neil Wedlock

J Dairy Sci· November 2018

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Self-Assembled Protein-Coated Polyhydroxyalkanoate Beads: Properties and Biomedical Applications.
Natalie A Parlane, Sandeep K Gupta, Patricia Rubio-Reyes, Shuxiong Chen, Majela Gonzalez-Miro, D Neil Wedlock

ACS Biomater Sci Eng· December 2017

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Immunological properties and protective efficacy of a single mycobacterial antigen displayed on polyhydroxybutyrate beads.
Patricia Rubio-Reyes, Natalie A Parlane, Bryce M Buddle, D Neil Wedlock, Bernd H A Rehm

Microb Biotechnol· November 2017

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Vaccination of Sheep with a Methanogen Protein Provides Insight into Levels of Antibody in Saliva Needed to Target Ruminal Methanogens.
Supatsak Subharat, Dairu Shu, Tao Zheng, Bryce M Buddle, Kan Kaneko, D Neil Wedlock

PLoS One· August 2017

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Bioengineering a bacterial pathogen to assemble its own particulate vaccine capable of inducing cellular immunity.
Jason W Lee, Natalie A Parlane, D Neil Wedlock, Bernd H A Rehm

Sci Rep· February 2017

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Corrigendum to "Immunogencity of antigens from Mycobacterium tuberculosis self-assembled as particulate vaccines" [Int. J. Med. Microbiol. 306 (2016) 624-632].
Patricia Rubio Reyes, Natalie A Parlane, D Neil Wedlock, Bernd H A Rehm

Int J Med Microbiol· February 2017

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Immunogencity of antigens from Mycobacterium tuberculosis self-assembled as particulate vaccines.
Patricia Rubio Reyes, Natalie A Parlane, D Neil Wedlock, Bernd H A Rehm

Int J Med Microbiol· December 2016

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Vaccination of cattle with a high dose of BCG vaccine 3 weeks after experimental infection with Mycobacterium bovis increased the inflammatory response, but not tuberculous pathology.
Bryce M Buddle, Dairu Shu, Natalie A Parlane, Supatsak Subharat, Axel Heiser, D Neil Wedlock

Tuberculosis (Edinb)· July 2016

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Display of Antigens on Polyester Inclusions Lowers the Antigen Concentration Required for a Bovine Tuberculosis Skin Test.
Natalie A Parlane, Shuxiong Chen, Gareth J Jones, H Martin Vordermeier, D Neil Wedlock

Clin Vaccine Immunol· January 2016

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Revaccination of cattle with bacille Calmette-Guérin two years after first vaccination when immunity has waned, boosted protection against challenge with Mycobacterium bovis.
Natalie A Parlane, Dairu Shu, Supatsak Subharat, D Neil Wedlock, Bernd H A Rehm

PLoS One· April 2015

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Vaccination of cattle with a methanogen protein produces specific antibodies in the saliva which are stable in the rumen.
Supatsak Subharat, Dairu Shu, Tao Zheng, Bryce M Buddle, Peter H Janssen, D Neil Wedlock

Vet Immunol Immunopathol· April 2015

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Grazing dairy cows had decreased interferon-γ, tumor necrosis factor, and interleukin-17, and increased expression of interleukin-10 during the first week after calving.
Axel Heiser, Allison McCarthy, Neil Wedlock, Susanne Meier, Jane Kay

J Dairy Sci· February 2015

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Dairy cows produce cytokine and cytotoxic T cell responses following vaccination with an antigenic fraction from Streptococcus uberis.
D Neil Wedlock, Bryce M Buddle, John Williamson, S Jane Lacy-Hulbert, Sally-Anne Turner

Vet Immunol Immunopathol· July 2014

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Comparison of gene expression of immune mediators in lung and pulmonary lymph node granulomas from cattle experimentally infected with Mycobacterium bovis.
Dairu Shu, Axel Heiser, D Neil Wedlock, Dongwen Luo, Geoffrey W de Lisle

Vet Immunol Immunopathol· July 2014

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New skin test for detection of bovine tuberculosis on the basis of antigen-displaying polyester inclusions produced by recombinant Escherichia coli.
Shuxiong Chen, Natalie A Parlane, Jason Lee, D Neil Wedlock, Bryce M Buddle

Appl Environ Microbiol· April 2014

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Subcutaneous administration of a 10-fold-lower dose of a commercial human tuberculosis vaccine, Mycobacterium bovis bacillus Calmette-Guerin Danish, induced levels of protection against bovine tuberculosis and responses in the tuberculin intradermal test similar to those induced by a standard cattle dose.
Bryce M Buddle, R Glyn Hewinson, H Martin Vordermeier, D Neil Wedlock

Clin Vaccine Immunol· October 2013

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