Publications by authors named "Nele Vandersickel"

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Reentry-driven model of atrial fibrillation is maintained by paired reentries and terminated by strategic pairwise virtual ablation.
Arthur S Bezerra, Robin Van Den Abeele, Bjorn Verstraeten, Sebastiaan Lootens, Arstanbek Okenov, Nele Vandersickel

Front Physiol· December 2025

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Paired reentries maintain ventricular tachycardia: a topological analysis of arrhythmic mechanisms using the index theorem.
Robin Van Den Abeele, Sebastiaan Lootens, Bjorn Verstraeten, Arthur Santos Bezerra, Arstanbek Okenov, Nele Vandersickel

Front Netw Physiol· November 2025

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Corrigendum to "Detection of regular rotational activity during cardiac arrhythmia using the Helmholtz decomposition for directed graphs." [Journal of Molecular and Cellular Cardiology 204 (2025) p40-54].
Sebastiaan Lootens, Robin Van Den Abeele, Vineesh Kappadan, Balvinder Handa, Matthias Duytschaever, Nele Vandersickel

J Mol Cell Cardiol· September 2025

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Detection of regular rotational activity during cardiac arrhythmia using the Helmholtz decomposition for directed graphs.
Sebastiaan Lootens, Robin Van den Abeele, Vineesh Kappadan, Balvinder Handa, Matthias Duytschaever, Nele Vandersickel

J Mol Cell Cardiol· July 2025

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How a Topological Mindset May Offer Extra Control During Mapping and Ablation of Left-Sided Reentrant Atrial Tachycardia.
Mattias Duytschaever, Maarten De Smet, Jordi Martens, Milad El Haddad, Benjamin De Becker, Nele Vandersickel

Circ Arrhythm Electrophysiol· July 2025

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Analysis and generation of the fibrosis textures based on histology data of the human hearts with non-ischemic cardiomyopathy.
Arstanbek Okenov, Timur Nezlobinsky, Claire A Glashan, Katja Zeppenfeld, Nele Vandersickel

Phys Med Biol· June 2025

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DGM-TOP: automatic identification of the critical boundaries in atrial tachycardia.
Robin Van Den Abeele, Sander Hendrickx, Niels Carlier, Eike M Wülfers, Arthur Santos Bezerra, Nele Vandersickel

Front Physiol· May 2025

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Small-molecule-induced ERBB4 activation to treat heart failure.
Julie M T Cools, Bo K Goovaerts, Eline Feyen, Siel Van den Bogaert, Yile Fu, Nele Vandersickel

Nat Commun· January 2025

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Atrial Topology for a Unified Understanding of Typical and Atypical Flutter.
Mattias Duytschaever, Robin Van den Abeele, Niels Carlier, Arthur Santos Bezerra, Bjorn Verstraeten, Nele Vandersickel

Circ Arrhythm Electrophysiol· November 2024

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Impact of topology on the number of loops during macro-re-entrant atrial tachycardia.
Nele Vandersickel, Sander Hendrickx, Robin Van den Abeele, Bjorn Verstraeten

Eur Heart J· May 2024

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Computer based method for identification of fibrotic scars from electrograms and local activation times on the epi- and endocardial surfaces of the ventricles.
Arstanbek Okenov, Timur Nezlobinsky, Katja Zeppenfeld, Nele Vandersickel, Alexander V Panfilov

PLoS One· April 2024

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Directed Graph Mapping exceeds Phase Mapping for the detection of simulated 2D meandering rotors in fibrotic tissue with added noise.
Sebastiaan Lootens, Iris Janssens, Robin Van Den Abeele, Eike M Wülfers, Arthur Santos Bezerra, Nele Vandersickel

Comput Biol Med· March 2024

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Directed Graph Mapping for Ventricular Tachycardia: A Comparison to Established Mapping Techniques.
Joshua Hawson, Enid Van Nieuwenhuyse, Robin Van Den Abeele, Ahmed Al-Kaisey, Robert D Anderson, Nele Vandersickel

JACC Clin Electrophysiol· July 2023

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Directed graph mapping shows rotors maintain non-terminating and focal sources maintain self-terminating Torsade de Pointes in canine model.
Robin Van Den Abeele, Sander Hendrickx, Enid Van Nieuwenhuyse, Albert Dunnink, Alexander V Panfilov, Nele Vandersickel

Front Physiol· July 2023

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DG-Mapping: a novel software package for the analysis of any type of reentry and focal activation of simulated, experimental or clinical data of cardiac arrhythmia.
Enid Van Nieuwenhuyse, Sander Hendrickx, Robin Van den Abeele, Bharathwaj Rajan, Lars Lowie, Nele Vandersickel

Med Biol Eng Comput· July 2022

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Finding type and location of the source of cardiac arrhythmias from the averaged flow velocity field using the determinant-trace method.
Qi-Hao Li, Enid Van Nieuwenhuyse, Yuan-Xun Xia, Jun-Ting Pan, Mattias Duytschaever, Nele Vandersickel

Phys Rev E· December 2021

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Evaluation of Directed Graph-Mapping in Complex Atrial Tachycardias.
Enid Van Nieuwenhuyse, Teresa Strisciuglio, Giuseppe Lorenzo, Milad El Haddad, Jan Goedgebeur, Nele Vandersickel

JACC Clin Electrophysiol· July 2021

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Directed graph mapping exceeds phase mapping in discriminating true and false rotors detected with a basket catheter in a complex in-silico excitation pattern.
Enid Van Nieuwenhuyse, Laura Martinez-Mateu, Javier Saiz, Alexander V Panfilov, Nele Vandersickel

Comput Biol Med· June 2021

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Gap19, a Cx43 Hemichannel Inhibitor, Acts as a Gating Modifier That Decreases Main State Opening While Increasing Substate Gating.
Alessio Lissoni, Nan Wang, Timur Nezlobinskii, Maarten De Smet, Alexander V Panfilov, Nele Vandersickel

Int J Mol Sci· October 2020

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Prospective evaluation of entrainment mapping as an adjunct to new-generation high-density activation mapping systems of left atrial tachycardias.
Teresa Strisciuglio, Nele Vandersickel, Giuseppe Lorenzo, Enid Van Nieuwenhuyse, Milad El Haddad

Heart Rhythm· February 2020

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R-From-T as a Common Mechanism of Arrhythmia Initiation in Long QT Syndromes.
Michael B Liu, Nele Vandersickel, Alexander V Panfilov, Zhilin Qu

Circ Arrhythm Electrophysiol· December 2019

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Directed Networks as a Novel Way to Describe and Analyze Cardiac Excitation: Directed Graph Mapping.
Nele Vandersickel, Enid Van Nieuwenhuyse, Nico Van Cleemput, Jan Goedgebeur, Milad El Haddad

Front Physiol· September 2019

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Dynamical anchoring of distant arrhythmia sources by fibrotic regions via restructuring of the activation pattern.
Nele Vandersickel, Masaya Watanabe, Qian Tao, Jan Fostier, Katja Zeppenfeld

PLoS Comput Biol· December 2018

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Effects of early afterdepolarizations on excitation patterns in an accurate model of the human ventricles.
Enid Van Nieuwenhuyse, Gunnar Seemann, Alexander V Panfilov, Nele Vandersickel

PLoS One· December 2017

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Short-Lasting Episodes of Torsade de Pointes in the Chronic Atrioventricular Block Dog Model Have a Focal Mechanism, While Longer-Lasting Episodes Are Maintained by Re-Entry.
Nele Vandersickel, Alexandre Bossu, Jan De Neve, Albert Dunnink, Veronique M F Meijborg

JACC Clin Electrophysiol· December 2017

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