Publications by authors named "Nelson Brown"

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Palbociclib-Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and Autophagy.
Angel Cayo, Whitney Venturini, Danitza Rebolledo-Mira, Rodrigo Moore-Carrasco, Andrés A Herrada, Nelson E Brown

Int J Mol Sci· May 2023

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Two New Adenosine Derivatives and their Antiproliferative Properties: An Evaluation.
Francisco Valdés, Bárbara Arévalo, Margarita Gutiérrez, Verónica García-Castillo, Rebeca Salgado-García, Nelson Brown

Anticancer Agents Med Chem· May 2022

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Platelets, a Key Cell in Inflammation and Atherosclerosis Progression.
Ricardo Huilcaman, Whitney Venturini, Lucia Fuenzalida, Angel Cayo, Raul Segovia, Nelson Brown

Cells· March 2022

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Endothelial transmigration of platelets depends on soluble factors released by activated endothelial cells and monocytes.
Ricardo Huilcaman, Natalia Veliz-Olivos, Whitney Venturini, Alexandra Olate-Briones, Adriana V Treuer, Nelson Brown

Platelets· November 2021

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mTOR Activity and Autophagy in Senescent Cells, a Complex Partnership.
Angel Cayo, Raúl Segovia, Whitney Venturini, Rodrigo Moore-Carrasco, Claudio Valenzuela, Nelson Brown

Int J Mol Sci· July 2021

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Platelet Activation Is Triggered by Factors Secreted by Senescent Endothelial HMEC-1 Cells In Vitro.
Whitney Venturini, Alexandra Olate-Briones, Claudio Valenzuela, Diego Méndez, Eduardo Fuentes, Nelson E Brown

Int J Mol Sci· May 2020

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Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines.
Rocio Cikutović-Molina, Andres A Herrada, Wendy González, Nelson Brown, Leandro Zúñiga

Int J Mol Sci· December 2019

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Adenosine Derivates as Antioxidant Agents: Synthesis, Characterization, in Vitro Activity, and Theoretical Insights.
Francisco Valdes, Nelson Brown, Alejandro Morales-Bayuelo, Luis Prent-Peñaloza, Margarita Gutierrez

Antioxidants (Basel)· October 2019

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SASP-Dependent Interactions between Senescent Cells and Platelets Modulate Migration and Invasion of Cancer Cells.
Claudio A Valenzuela, Ricardo Quintanilla, Alexandra Olate-Briones, Whitney Venturini, Daniel Mancilla, Nelson E Brown

Int J Mol Sci· October 2019

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Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity.
Francisco Z Valdés, Víctor Z Luna, Bárbara R Arévalo, Nelson V Brown, Margarita C Gutiérrez

Mini Rev Med Chem· December 2018

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TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines.
Rafael Zúñiga, Claudio Valenzuela, Guierdy Concha, Nelson Brown, Leandro Zúñiga

Int J Mol Sci· March 2018

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Palbociclib-induced autophagy and senescence in gastric cancer cells.
Claudio A Valenzuela, Leandro Vargas, Valentina Martinez, Sindy Bravo, Nelson E Brown

Exp Cell Res· November 2017

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The Potential Role of Senescence As a Modulator of Platelets and Tumorigenesis.
Claudio A Valenzuela, Ricardo Quintanilla, Rodrigo Moore-Carrasco, Nelson E Brown

Front Oncol· August 2017

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Expression and cellular localization of HCN channels in rat cerebellar granule neurons.
Rafael Zúñiga, Daniela González, Claudio Valenzuela, Nelson Brown, Leandro Zúñiga

Biochem Biophys Res Commun· September 2016

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Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence.
Maja Sedic, Adam Skibinski, Nelson Brown, Mercedes Gallardo, Peter Mulligan

Nat Commun· June 2015

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The selective cytotoxicity elicited by phytochemical extract from Senecio graveolens (Asteraceae) on breast cancer cells is enhanced by hypoxia.
Carlos Echiburú-Chau, Susana Alfaro-Lira, Nelson Brown, Cristian O Salas, Mauricio Cuellar

Int J Oncol· April 2014

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Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium.
Nelson E Brown, Rinath Jeselsohn, Teeru Bihani, Miaofen G Hu, Parthena Foltopoulou

Cancer Res· December 2012

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Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis.
Rinath Jeselsohn, Nelson E Brown, Lisa Arendt, Ina Klebba, Miaofen G Hu

Cancer Cell· January 2010

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Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice.
Gabriel M Gutierrez, Elizabeth Kong, Yves Sabbagh, Nelson E Brown, Jong-Seo Lee

Proc Natl Acad Sci U S A· November 2008

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The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development.
Mark W Landis, Nelson E Brown, Gregory L Baker, Anna Shifrin, Manjusri Das

Cancer Res· August 2007

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A truncated polycystin-2 protein causes polycystic kidney disease and retinal degeneration in transgenic rats.
Anna Rachel Gallagher, Sigrid Hoffmann, Nelson Brown, Anna Cedzich, Sujatha Meruvu

J Am Soc Nephrol· October 2006

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Use of the tetracycline system for inducible protein synthesis in the kidney.
Anna Rachel Gallagher, Kai Schönig, Nelson Brown, Hermann Bujard, Ralph Witzgall

J Am Soc Nephrol· August 2003

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