Publications by authors named "Nesar Akanda"

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Developing a functional non-animal CNS stress model utilizing long-term potentiation with human iPSC-cortical neurons to evaluate therapeutics.
Kaveena Autar, Xiufang Guo, Haley Powell, Aakash Patel, Mridu Malik, Nesar Akanda

Biomed Pharmacother· November 2025

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Establishment of a Serum-Free Human iPSC-Derived Model of Peripheral Myelination.
Aakash Patel, Marnie Williams, Kenneth Hawkins, Leandro Gallo, Marcella Grillo, Nesar Akanda

ACS Biomater Sci Eng· November 2024

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Validation of a functional human AD model with four AD therapeutics utilizing patterned ipsc-derived cortical neurons integrated with microelectrode arrays.
Julbert Caneus, Kaveena Autar, Nesar Akanda, Marcella Grillo, Christopher J Long

Sci Rep· October 2024

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A functional aged human iPSC-cortical neuron model recapitulates Alzheimer's disease, senescence, and the response to therapeutics.
Leandro H Gallo, Nesar Akanda, Kaveena Autar, Aakash Patel, Ian Cox

Alzheimers Dement· September 2024

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Human IPSC-Derived PreBötC-Like Neurons and Development of an Opiate Overdose and Recovery Model.
Xiufang Guo, Nesar Akanda, Gabriella Fiorino, Siddharth Nimbalkar, Christopher J Long

Adv Biol (Weinh)· August 2024

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Validation of a functional human AD model with four AD therapeutics utilizing patterned iPSC-derived cortical neurons integrated with microelectrode arrays.
Julbert Caneus, Kaveena Autar, Nesar Akanda, Marcella Grillo, Chris Long

Res Sq· May 2024

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Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing.
Siddharth Nimbalkar, Xiufang Guo, Alisha Colón, Max Jackson, Nesar Akanda

Front Cell Dev Biol· March 2023

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An induced pluripotent stem cell-derived NMJ platform for study of the NGLY1-Congenital Disorder of Deglycosylation.
Trevor Sasserath, Ashley L Robertson, Roxana Mendez, Tristan T Hays, Ethan Smith, Nesar Akanda

Adv Ther (Weinh)· November 2022

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A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders.
Kaveena Autar, Xiufang Guo, John W Rumsey, Christopher J Long, Nesar Akanda

Stem Cell Reports· January 2022

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A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ and tau-induced pathophysiological effects on long-term potentiation.
Julbert Caneus, Nesar Akanda, John W Rumsey, Xiufang Guo, Max Jackson

Alzheimers Dement (N Y)· May 2020

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Evaluation of Holistic Treatment for ALS Reveals Possible Mechanism and Therapeutic Potential.
Andrea Lavado, Xiufang Guo, Alec St Smith, Nesar Akanda, Candace Martin

Int J Pharm Pharm Res· December 2017

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Tissue engineering the mechanosensory circuit of the stretch reflex arc with human stem cells: Sensory neuron innervation of intrafusal muscle fibers.
Xiufang Guo, Alisha Colon, Nesar Akanda, Severo Spradling, Maria Stancescu

Biomaterials· April 2017

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Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems.
Bonnie J Berry, Nesar Akanda, Alec S T Smith, Christopher J Long, Mark T Schnepper

Biotechnol Prog· October 2016

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Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs.
Carlota Oleaga, Catia Bernabini, Alec S T Smith, Balaji Srinivasan, Max Jackson, Nesar Akanda

Sci Rep· February 2016

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In vitro Differentiation of Functional Human Skeletal Myotubes in a Defined System.
Xiufang Guo, Keshel Greene, Nesar Akanda, Alec Smith, Maria Stancescu

Biomater Sci· January 2014

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Analysis of toxin-induced changes in action potential shape for drug development.
Nesar Akanda, Peter Molnar, Maria Stancescu, James J Hickman

J Biomol Screen· December 2009

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Voltage-dependent anion channels (VDAC) in the plasma membrane play a critical role in apoptosis in differentiated hippocampal neurons but not in neural stem cells.
Nesar Akanda, Roshan Tofighi, Johan Brask, Christoffer Tamm, Fredrik Elinder

Cell Cycle· October 2008

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Biophysical properties of the apoptosis-inducing plasma membrane voltage-dependent anion channel.
Nesar Akanda, Fredrik Elinder

Biophys J· June 2006

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