Publications by authors named "Nezar Boreak"

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Molecular docking and MD simulations predicted quercetin as a potent human interleukin-1 beta (hIL1β) inhibitor for improved endodontic disease management.
Nezar Boreak, Shroog Ali Almasoudi, Abdulelah Alharbi, Mona Judayba, Shahd Tahrei

PLoS One· December 2025

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Assessment of Fatigue Resistance in Heat-treated Nickel-titanium Rotary Instruments with Single Canal Curvatures: An Evaluation.
Nezar Boreak

J Contemp Dent Pract· November 2025

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Molecular signatures of endodontitis and pulpal inflammation: a comprehensive gene expression and multi-parameter analysis using GSE77459 microarray data.
Nezar Boreak

Cell Mol Biol (Noisy-le-grand)· April 2025

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Harnessing the antimicrobial potential of Aegle marmelos against Mfa1 fimbriae in Porphyromonas gingivalis: a new strategy for endodontic therapy.
Nezar Boreak, Noor Eissa Mousa Jaferi, Mohammed Bashery, Hanan Salem Otudi, Abdullah Saad Almuqbil

Cell Mol Biol (Noisy-le-grand)· February 2025

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Genomic insights into Enterococcus faecalis implicated in endodontic infections: resistance, virulence, and genetic variability.
Nezar Boreak, Ahlam Abdu Mohammed Mowkly, Amnah Sharwani, Shroog Ali Almasoudi, Ahmed Huraysi

Cell Mol Biol (Noisy-le-grand)· February 2025

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Targeting acetate kinase of Porphyromonas gingivalis: a computational approach to identifying novel inhibitors for endodontic infection treatment.
Nezar Boreak, Shatha Ahmad Jafari, Huriyyah Meshal Alotaibi, Thekra Saud Abdullah Abbas, Abdullah Mohammed Bokar

Cell Mol Biol (Noisy-le-grand)· February 2025

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Exploring Plant-Based Compounds as Alternatives for Targeting in Endodontic Therapy: A Molecular Docking Approach.
Nezar Boreak, Rahf Zuhair Al Mahde, Waseem Ahmed Otayn, Amwaj Yahya Alamer, Taif Alrajhi

Int J Mol Sci· July 2024

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Surgical Extrusion of Three Premolars to Re-establish the Biological Width: Case Series.
Nezar Boreak, Mohammed M Al Moaleem, Asma A Zain, Alfaroog Madkhali, Layla M Arishy

J Contemp Dent Pract· June 2024

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Unveiling Therapeutic Potential: Targeting 's Lipopolysaccharide Biosynthesis for Endodontic Infections-An In Silico Screening Study.
Nezar Boreak, Ethar Awad Alrajab, Rayan Ali Nahari, Loay Ebrahim Najmi, Muhannad Ali Masmali

Int J Mol Sci· April 2024

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Radiographic Assessment of 121 Glass Fiber Post Procedures in 32 Patients Aged 21-60 Years Performed by 6th-Year Dental Students During the 2022-2023 Academic Year at the College of Dentistry, Jazan University, Saudi Arabia.
Abdulkarim H Alshehri, Khalid Dhafer Alhendi, Raid Abdullah Almnea, Ahmed A Alelyani, Thrya S Gadah, Nezar Boreak

Med Sci Monit· March 2024

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A Systematic Review of Publications on Perceptions and Management of Chronic Medical Conditions Using Telemedicine Remote Consultations by Primary Healthcare Professionals April 2020 to December 2021 During the COVID-19 Pandemic.
Arzaq Ahmed, Mahdi Mutahar, Arwa A Daghrery, Nassreen H Albar, Ismail Qasem I Alhadidi, Nezar Boreak

Med Sci Monit· February 2024

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Evaluation of Cytotoxicity of Calcium Silicate-based Mineral Trioxide Aggregate Sealers: A Systematic Review of Studies.
Nezar Mohammed Boreak, Mazen Ahmed Qadi, Faisal Hadi Khormi, Luay Mutaen Faqiri, Sadeem Omar Zaylai

J Contemp Dent Pract· August 2023

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Evaluation of Micro-Tensile Bond Strength of Fibre Post with Titanium Dioxide Nanoparticles as Fillers in Experimental Dental Composite Resin.
Dhanasekaran Sihivahanan, Mavishna Maniyan Vijayakumari, Pradeep Kumar Yadalam, Nezar Boreak, Sultan Binalrimal

Materials (Basel)· May 2022

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Effect of Different Intracanal Medicaments on the Viability and Survival of Dental Pulp Stem Cells.
Shilpa Bhandi, Shankargouda Patil, Nezar Boreak, Hitesh Chohan, Abdulaziz S AbuMelha

J Pers Med· April 2022

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In-Silico modulation of Interleukin-8 (IL8) for the therapeutic management of endodontic pulpitis.
Nezar Boreak, Shilpa Bhandi

Saudi J Biol Sci· February 2022

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Study of optimal conditions for growth and osteogenic differentiation of dental pulp stem cells based on glucose and serum content.
Shilpa Bhandi, Ahmed Alkahtani, Mohammed Mashyakhy, Hosam Ali Baeshen, Mohammed Mustafa, Nezar Boreak

Saudi J Biol Sci· November 2021

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Adipogenic Stimulation and Pyrrolidine Dithiocarbamate Induced Osteogenic Inhibition of Dental Pulp Stem Cells Is Countered by Cordycepin.
Shankargouda Patil, Rodolfo Reda, Nezar Boreak, Hasan Ahmad Taher, Abdulaziz Abu Melha

J Pers Med· September 2021

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Metformin pre-conditioning enhances the angiogenic ability of the secretome of dental pulp stem cells.
Nezar Boreak, Noor Mohammed Abu Khayrat, Ahmed Omar Shami, Haitham Jameel Mohammed Zaylaee, Aeshah Ali Hanbashi

Saudi Pharm J· August 2021

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Dose-Dependent Effect of Cordycepin on Viability, Proliferation, Cell Cycle, and Migration in Dental Pulp Stem Cells.
Nezar Boreak, Ahmed Alkahtani, Khalid Alzahrani, Amani Hassan Kenani, Wafa Hussain Faqehi

J Pers Med· July 2021

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Small Molecule "Silmitasertib" Repurposed as Inhibitor of Transforming Growth Factor Beta 1 for the Development of Therapeutics for Oral Submucous Fibrosis.
Nezar Boreak

Biomed Res Int· May 2021

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Parathyroid Hormone Secretion and Receptor Expression Determine the Age-Related Degree of Osteogenic Differentiation in Dental Pulp Stem Cells.
Shilpa Bhandi, Ahmed Alkahtani, Rodolfo Reda, Mohammed Mashyakhy, Nezar Boreak

J Pers Med· April 2021

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Effectiveness of Artificial Intelligence Applications Designed for Endodontic Diagnosis, Decision-making, and Prediction of Prognosis: A Systematic Review.
Nezar Boreak

J Contemp Dent Pract· August 2020

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Analysis of sugars and pH in commercially available soft drinks in Saudi Arabia with a brief review on their dental implications.
Ali Mohamed Idris, Nandimandalam Venkata Vani, Dhafi A Almutari, Mohammed A Jafar, Nezar Boreak

J Int Soc Prev Community Dent· December 2016

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In vitro comparison of antibacterial properties of bioceramic-based sealer, resin-based sealer and zinc oxide eugenol based sealer and two mineral trioxide aggregates.
Gurpreet Singh, Iti Gupta, Faheim M M Elshamy, Nezar Boreak, Husham Elraih Homeida

Eur J Dent· July 2016

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An in vitro Comparison of Antimicrobial Activity of Three Endodontic Sealers with Different Composition.
Gurpreet Singh, Faheim Mm Elshamy, Husham E Homeida, Nezar Boreak, Iti Gupta

J Contemp Dent Pract· July 2016

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