Publications by authors named "Nhat Tu Le"

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SHP2: A Redox-Sensitive Regulator Linking Immune Checkpoint Inhibitor Therapy to Cancer Treatment and Vascular Risk.
Silvia Fernanda López Moreno, Stefania Assunto Lenz, Bernardo Casso-Chapa, Angelica Paniagua-Bojorges, Jung Hyun Kim, Jonghae Lee, Michelle A T Hildebrandt, Keri Schadler, Nhat-Tu Le

Antioxidants (Basel)· November 2025

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APOA1 binding protein promotes lymphatic cell fate and lymphangiogenesis by relieving caveolae-mediated inhibition of VEGFR3 signaling.
Jun-Dae Kim, Surbhi Chaudhary, Weiqing Chen, Jonathan Astin, Philip S Crosier, Hugo J Bellen, Nhat-Tu Le, Stanley G Rockson

Nat Commun· October 2025

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Impacts of Radiation on Metabolism and Vascular Cell Senescence.
Junichi Abe, Khanh Chau, Anahita Mojiri, Guangyu Wang, Masayoshi Oikawa, Nhat-Tu Le

Antioxid Redox Signal· July 2025

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A visual-omics foundation model to bridge histopathology with spatial transcriptomics.
Weiqing Chen, Pengzhi Zhang, Tu N Tran, Yiwei Xiao, Shengyu Li, Nhat-Tu Le

Nat Methods· July 2025

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TNIK-driven regulation of ERK5 transcriptional activity in endothelial cells.
Venkata Subrahmanya Kumar Samanthapudi, Sivareddy Kotla, Nhat-Tu Le

Front Cardiovasc Med· July 2025

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Editorial: Functions and regulation of p90RSK and its family: mechanisms, roles in diseases, and implications in therapeutics.
Ling Lin, Nhat-Tu Le, Kebin Hu

Front Cell Dev Biol· July 2025

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Downregulation of LATS1/2 Drives Endothelial Senescence-Associated Stemness (SAS) and Atherothrombotic Lesion Formation.
Sivareddy Kotla, Jonghae Lee, Kyung Ae Ko, Weiqing Chen, Venkata Subrahmanya Kumar Samanthapudi, Keri L Schadler, Kay Carlene Tavares Samperio, Erin H Seeley, Nhat-Tu Le

bioRxiv· June 2025

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A visual-omics foundation model to bridge histopathology image with transcriptomics.
Weiqing Chen, Pengzhi Zhang, Tu N Tran, Yiwei Xiao, Shengyu Li, Nhat-Tu Le

Res Sq· April 2025

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Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease.
Bernardo Casso-Chapa, Norma Alicia Vazquez González, Nhat-Tu Le, Nicolas L Palaskas, Kevin T Nead, Jonghae Lee, Erin Seeley, Keri Schadler

Arterioscler Thromb Vasc Biol· March 2025

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A Potential Role for MAGI-1 in the Bi-Directional Relationship Between Major Depressive Disorder and Cardiovascular Disease.
Priyanka Banerjee, Khanh Chau, Sivareddy Kotla, Eleanor L Davis, Estefani Berrios Turcios, Nhat-Tu Le

Curr Atheroscler Rep· September 2024

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A relay velocity model infers cell-dependent RNA velocity.
Shengyu Li, Pengzhi Zhang, Weiqing Chen, Lingqun Ye, Kristopher W Brannan, Nhat-Tu Le

Nat Biotechnol· January 2024

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TNIK regulation of interferon signaling and endothelial cell response to virus infection.
Khanh M Chau, Abishai Dominic, Eleanor L Davis, Sivareddy Kotla, Estefani Turcios Berrios, Nhat-Tu Le

Front Cardiovasc Med· January 2024

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Premature senescence and cardiovascular disease following cancer treatments: mechanistic insights.
Ashita Jain, Diego Casanova, Alejandra Valdivia Padilla, Angelica Paniagua Bojorges, Sivareddy Kotla, Selina L Hernandez Gonzalez, Dale J Hamilton, Xiaolei Xu, Nhat-Tu Le

Front Cardiovasc Med· September 2023

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The significance of ERK5 catalytic-independent functions in disease pathways.
Nhat-Tu Le

Front Cell Dev Biol· August 2023

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Metabolic regulation of endothelial senescence.
Nhat-Tu Le

Front Cardiovasc Med· August 2023

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Endothelial activation and fibrotic changes are impeded by laminar flow-induced CHK1-SENP2 activity through mechanisms distinct from endothelial-to-mesenchymal cell transition.
Minh T H Nguyen, Masaki Imanishi, Shengyu Li, Khanh Chau, Priyanka Banerjee, Ling-Ling Lee, Elena McBeath, Nhat-Tu Le

Front Cardiovasc Med· August 2023

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An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis.
Jun-Ichi Abe, Masaki Imanishi, Shengyu Li, Aijun Zhang, Kyung Ae Ko, Ling-Ling Lee, Keri L Schadler, Dale J Hamilton, Nhat-Tu Le

Circ Res· June 2023

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Possible molecular mechanisms underlying the development of atherosclerosis in cancer survivors.
Priyanka Banerjee, Julia Enterría Rosales, Khanh Chau, Minh T H Nguyen, Sivareddy Kotla, Nhat-Tu Le

Front Cardiovasc Med· June 2023

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Metabolic dysregulation impairs lymphocyte function during severe SARS-CoV-2 infection.
Sanjeev Gurshaney, Anamaria Morales-Alvarez, Kevin Ezhakunnel, Andrew Manalo, Thien-Huong Huynh, Nhat-Tu Le, Alessandro Sette

Commun Biol· April 2023

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Radiation therapy induces immunosenescence mediated by p90RSK.
Masaki Imanishi, Haizi Cheng, Sivareddy Kotla, Anita Deswal, Nhat-Tu Le, Ling-Ling Lee, Xiaolei Xu, Keri L Schadler

Front Cardiovasc Med· November 2022

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MAGI1 inhibits interferon signaling to promote influenza A infection.
Yin Wang, Jun-Ichi Abe, Khanh M Chau, Yongxing Wang, Hang Thi Vu, Ling-Ling Lee, Nhat-Tu Le

Front Cardiovasc Med· August 2022

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Free Cholesterol Bioavailability and Atherosclerosis.
Rei J Abe, Jun-Ichi Abe, Minh T H Nguyen, Elizabeth A Olmsted-Davis, Abrar Mamun, Nhat-Tu Le

Curr Atheroscler Rep· May 2022

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Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications.
Priyanka Banerjee, Elizabeth A Olmsted-Davis, Anita Deswal, Minh Th Nguyen, Efstratios Koutroumpakis, Keri Schadler, Nhat-Tu Le

J Cardiovasc Aging· April 2022

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Paradoxical effects of osteoprotegerin on vascular function: inhibiting inflammation while promoting oxidative stress?
Nhat-Tu Le, Elizabeth A Olmsted-Davis, Jun-Ichi Abe

Clin Sci (Lond)· March 2022

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Senescence-Associated Secretory Phenotype as a Hinge Between Cardiovascular Diseases and Cancer.
Priyanka Banerjee, Sivareddy Kotla, Loka Reddy Velatooru, Rei J Abe, Elizabeth A Davis, Keri Schadler, Nhat-Tu Le

Front Cardiovasc Med· October 2021

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