Publications by authors named "Nicholas A Bright"

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Plasma membrane remodeling in GM2 gangliosidoses drives synaptic dysfunction.
Alex S Nicholson, David A Priestman, Robin Antrobus, James C Williamson, Reuben Bush, Nicholas A Bright

PLoS Biol· July 2025

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Electron Tomography of Organelles and Vesicles in the Investigation of SNARE Function and Localization.
Nicholas A Bright, J Paul Luzio

Methods Mol Biol· May 2025

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A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein synthesis regulation.
Sophia Y Breusegem, Jack Houghton, Raquel Romero-Bueno, Adrián Fragoso-Luna, Katherine A Kentistou, Nicholas A Bright

Nat Commun· February 2025

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VAMP2 regulates phase separation of α-synuclein.
Aishwarya Agarwal, Aswathy Chandran, Farheen Raza, Irina-Maria Ungureanu, Christine Hilcenko, Nicholas A Bright

Nat Cell Biol· August 2024

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Reversible assembly and disassembly of V-ATPase during the lysosome regeneration cycle.
Ioana Sava, Luther J Davis, Sally R Gray, Nicholas A Bright, J Paul Luzio

Mol Biol Cell· May 2024

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Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A.
Elena V Pavlova, Dorit Lev, Marina Michelson, Keren Yosovich, Hila Gur Michaeli, Nicholas A Bright

Hum Mutat· December 2022

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Organelle tethering, pore formation and SNARE compensation in the late endocytic pathway.
Luther J Davis, Nicholas A Bright, James R Edgar, Michael D J Parkinson, Lena Wartosch

J Cell Sci· May 2021

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Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29.
Harriet Crawley-Snowdon, Ji-Chun Yang, Nathan R Zaccai, Luther J Davis, Lena Wartosch, Nicholas A Bright

Nat Commun· October 2020

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The lysosomal disease caused by mutant VPS33A.
Elena V Pavlova, Aleksey Shatunov, Lena Wartosch, Alena I Moskvina, Lena E Nikolaeva, Nicholas A Bright

Hum Mol Genet· August 2019

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The Lysosome and Intracellular Signalling.
Geoffrey G Hesketh, Lena Wartosch, Luther J Davis, Nicholas A Bright, J Paul Luzio

Prog Mol Subcell Biol· February 2019

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Exosomes bind to autotaxin and act as a physiological delivery mechanism to stimulate LPA receptor signalling in cells.
Susanna A Jethwa, Emma J Leah, Qifeng Zhang, Nicholas A Bright, David Oxley

J Cell Sci· October 2016

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Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity.
Nicholas A Bright, Luther J Davis, J Paul Luzio

Curr Biol· September 2016

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Lysosome fusion in cultured mammalian cells.
Nicholas A Bright, Lena Wartosch, J Paul Luzio

Methods Cell Biol· October 2015

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A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I.
Michael D J Parkinson, Siân C Piper, Nicholas A Bright, Jennifer L Evans, Jessica M Boname

Biochem J· October 2015

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Lysosomes.
Lena Wartosch, Nicholas A Bright, J Paul Luzio

Curr Biol· April 2015

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CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.
Sharon E Miller, Signe Mathiasen, Nicholas A Bright, Fabienne Pierre, Bernard T Kelly

Dev Cell· April 2015

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The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation.
Ingmar B Schäfer, Geoffrey G Hesketh, Nicholas A Bright, Sally R Gray, Paul R Pryor

Nat Struct Mol Biol· December 2012

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Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome.
David A Tumbarello, Bennett J Waxse, Susan D Arden, Nicholas A Bright, John Kendrick-Jones

Nat Cell Biol· October 2012

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Endosome-lysosome fusion.
J Paul Luzio, Sally R Gray, Nicholas A Bright

Biochem Soc Trans· December 2010

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The sodium/proton exchanger NHE8 regulates late endosomal morphology and function.
Scott P Lawrence, Nicholas A Bright, J Paul Luzio, Katherine Bowers

Mol Biol Cell· October 2010

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The autoimmunity-related GIMAP5 GTPase is a lysosome-associated protein.
Vivian Wy Wong, Amy E Saunders, Amanda Hutchings, John C Pascall, Christine Carter, Nicholas A Bright

Self Nonself· July 2010

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Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C.
Rhys C Roberts, Andrew A Peden, Folma Buss, Nicholas A Bright, Morwena Latouche

Hum Mol Genet· March 2010

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The delivery of endocytosed cargo to lysosomes.
J Paul Luzio, Michael D J Parkinson, Sally R Gray, Nicholas A Bright

Biochem Soc Trans· October 2009

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SDPR induces membrane curvature and functions in the formation of caveolae.
Carsten G Hansen, Nicholas A Bright, Gillian Howard, Benjamin J Nichols

Nat Cell Biol· July 2009

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ESCRT proteins and the regulation of endocytic delivery to lysosomes.
J Paul Luzio, Siân C Piper, Katherine Bowers, Michael D J Parkinson, Paul J Lehner, Nicholas A Bright

Biochem Soc Trans· February 2009

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