Publications by authors named "Nicholas A Graham"

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Carboxy-Methylation of the Catalytic Subunit of Protein Phosphatase 2A (PP2Ac) Integrates Methionine Availability with Methionine Addicted Cancer Cell Proliferation.
Anna Andronicos, Kiku C Yoneda, Da-Wei Lin, Fiona V Law, Hosung Bae, Nicholas A Graham

Biomolecules· August 2025

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Integrated multi-omic characterizations of the synapse reveal RNA processing factors and ubiquitin ligases associated with neurodevelopmental disorders.
Yuan Mei, Maya L Gosztyla, Xinzhu Tan, Lara E Dozier, Brent Wilkinson, Nicholas A Graham

Cell Syst· April 2025

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WITHDRAWN: Single-Cell Heterogeneity of EGFR Pathway Is Linked to Unique Signatures of Drug Response and Malignancy in Patient Derived Glioblastoma Stem Cells.
Michael D Masterman-Smith, Nicholas A Graham, Eduard H Panosyan, Jack Mottahedeh, Eric R Samuels

Cancer Res Treat· January 2025

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Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer.
Niki Tavakoli, Emma J Fong, Abigail Coleman, Yu-Kai Huang, Mathias Bigger, Nicholas A Graham

NPJ Syst Biol Appl· January 2025

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Merging Metabolic Modeling and Imaging for Screening Therapeutic Targets in Colorectal Cancer.
Niki Tavakoli, Emma J Fong, Abigail Coleman, Yu-Kai Huang, Mathias Bigger, Nicholas A Graham

bioRxiv· December 2024

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Mutations in the postsynaptic density signaling hub TNIK disrupt PSD signaling in human models of neurodevelopmental disorders.
Jianzhi Jiang, Brent Wilkinson, Ilse Flores, Nicolas Hartel, Simeon R Mihaylov, Nicholas A Graham

Front Mol Neurosci· April 2024

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A naturally occurring variant of SHLP2 is a protective factor in Parkinson's disease.
Su-Jeong Kim, Brendan Miller, Nicolas G Hartel, Ricardo Ramirez, Regina Gonzalez Braniff, Nicholas A Graham

Mol Psychiatry· February 2024

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Functional and phosphoproteomic analysis of β-adrenergic receptor signaling at excitatory synapses in the CA1 region of the ventral hippocampus.
Shekib A Jami, Brent J Wilkinson, Ryan Guglietta, Nicolas Hartel, Walter E Babiec, Nicholas A Graham

Sci Rep· May 2023

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Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing.
Belinda B Garana, James H Joly, Alireza Delfarah, Hyunjun Hong, Nicholas A Graham

BMC Bioinformatics· May 2023

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The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biology.
Tiffany L vanLieshout, Derek W Stouth, Nicolas G Hartel, Goutham Vasam, Sean Y Ng, Nicholas A Graham

Mol Metab· October 2022

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Kinetic and data-driven modeling of pancreatic β-cell central carbon metabolism and insulin secretion.
Patrick E Gelbach, Dongqing Zheng, Scott E Fraser, Kate L White, Nicholas A Graham

PLoS Comput Biol· October 2022

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Phospho-proteomics reveals that RSK signaling is required for proliferation of natural killer cells stimulated with IL-2 or IL-15.
Melanie A MacMullan, Pin Wang, Nicholas A Graham

Cytokine· September 2022

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SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis.
Chao Qin, Youliang Rao, Hao Yuan, Ting-Yu Wang, Jun Zhao, Nicholas A Graham

Proc Natl Acad Sci U S A· June 2022

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Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time.
Tong Xu, Jason A Junge, Alireza Delfarah, Yi-Tsung Lu, Cosimo Arnesano, Nicholas A Graham

Sci Rep· April 2022

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Glutamine-dependent signaling controls pluripotent stem cell fate.
Vivian Lu, Irena J Roy, Alejandro Torres, James H Joly, Fasih M Ahsan, Nicholas A Graham

Dev Cell· March 2022

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Metabolomics paves the way for improved drug target identification.
Belinda B Garana, Nicholas A Graham

Mol Syst Biol· February 2022

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Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics.
Junmin Wang, Alireza Delfarah, Patrick E Gelbach, Emma Fong, Paul Macklin, Nicholas A Graham

Metab Eng· January 2022

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Identification of a Proteomic Signature of Senescence in Primary Human Mammary Epithelial Cells.
Alireza Delfarah, Nicolas G Hartel, DongQing Zheng, Jesse Yang, Nicholas A Graham

J Proteome Res· November 2021

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Bayesian metamodeling of complex biological systems across varying representations.
Barak Raveh, Liping Sun, Kate L White, Tanmoy Sanyal, Jeremy Tempkin, Nicholas A Graham

Proc Natl Acad Sci U S A· August 2021

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The landscape of metabolic pathway dependencies in cancer cell lines.
James H Joly, Brandon T L Chew, Nicholas A Graham

PLoS Comput Biol· April 2021

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Differential Gene Set Enrichment Analysis: a statistical approach to quantify the relative enrichment of two gene sets.
James H Joly, William E Lowry, Nicholas A Graham

Bioinformatics· January 2021

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MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis.
Joseph C Reynolds, Rochelle W Lai, Jonathan S T Woodhead, James H Joly, Cameron J Mitchell, Nicholas A Graham

Nat Commun· January 2021

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Photo-Triggered Delivery of siRNA and Paclitaxel into Breast Cancer Cells Using Catanionic Vesicles.
Zumra Peksaglam Seidel, Xiaoyang Zhang, Melanie A MacMullan, Nicholas Alexander Graham, Pin Wang

ACS Appl Bio Mater· November 2020

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Improved Discrimination of Asymmetric and Symmetric Arginine Dimethylation by Optimization of the Normalized Collision Energy in Liquid Chromatography-Mass Spectrometry Proteomics.
Nicolas G Hartel, Christopher Z Liu, Nicholas A Graham

J Proteome Res· August 2020

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Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis.
Jun Zhao, Mao Tian, Shu Zhang, Alireza Delfarah, Ruoyun Gao, Nicholas A Graham

Cell Metab· May 2020

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