Publications by authors named "Nicholas Bertos"

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Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett's Esophagus to adenocarcinoma.
Michael K Strasser, David L Gibbs, Philippe Gascard, Joanna Bons, John W Hickey, Nicholas Bertos

Dev Cell· October 2025

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A fibroblast-centric network drives cold fibrosis in the tumor microenvironment of lung squamous cell carcinoma.
Shoval Miyara, Shachaf Frenkel, Avi Mayo, Philippe Gascard, Michael Strasser, Nicholas Bertos

bioRxiv· August 2025

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A Fibroblast State Choreographs an Epithelial YAP-dependent Regenerative Program Essential to (Pre)malignancy via ECM-mediated Mechanotransduction.
Deng Pan, Philippe Gascard, Joseph A Caruso, Chira Chen-Tanyolac, Veena Sangwan, Nicholas Bertos

bioRxiv· July 2025

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Patient-derived esophageal adenocarcinoma organ chip: a physiologically relevant platform for functional precision oncology.
Sanjima Pal, Elee Shimshoni, Salvador Flores Torres, Mingyang Kong, Kulsum Tai, Nicholas Bertos

J Transl Med· May 2025

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Phase 2 trial of perioperative chemo-immunotherapy for gastro-esophageal adenocarcinoma: The role of M2 macrophage landscape in predicting response.
Thierry Alcindor, James Tankel, Pierre-Olivier Fiset, Sanjima Pal, Touhid Opu, Nicholas Bertos

Cell Rep Med· April 2025

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HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer.
Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H White, Katelyn L Mortenson, Nicholas Bertos

Cancer Res· July 2024

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Bioprinted Multicomponent Hydrogel Co-culture Tumor-Immune Model for Assessing and Simulating Tumor-Infiltrated Lymphocyte Migration and Functional Activation.
Salvador Flores-Torres, Nikolaos M Dimitriou, Lucas Antonio Pardo, Jacqueline Kort-Mascort, Sanjima Pal, Nicholas Bertos

ACS Appl Mater Interfaces· July 2023

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Constructing 3D In Vitro Models of Heterocellular Solid Tumors and Stromal Tissues Using Extrusion-Based Bioprinting.
Salvador Flores-Torres, Tao Jiang, Jacqueline Kort-Mascort, Yun Yang, Omar Peza-Chavez, Nicholas Bertos

ACS Biomater Sci Eng· February 2023

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Relation between mismatch repair status, chemoresponse, survival and anatomic location in gastroesophageal adenocarcinoma.
Gertruda Evaristo, Amit Katz, José L Ramírez-GarcíaLuna, Marianne S M Issac, Veena Sangwan, Nicholas Bertos

Can J Surg· February 2023

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Soluble factors in malignant ascites promote the metastatic adhesion of gastric adenocarcinoma cells.
Luai Al-Marzouki, Vivian S Stavrakos, Sanjima Pal, Betty Giannias, France Bourdeau, Nicholas Bertos

Gastric Cancer· January 2023

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Improved platform for breast cancer circulating tumor cell enrichment and characterization with next-generation sequencing technology.
Catalin Mihalcioiu, Jiarong Li, Dunarel Badescu, Anne Camirand, Nathaniel Kremer, Nicholas Bertos

Am J Cancer Res· January 2023

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Inhibition of LPS-mediated TLR4 activation abrogates gastric adenocarcinoma-associated peritoneal metastasis.
Veena Sangwan, Luai Al-Marzouki, Sanjima Pal, Vivian Stavrakos, Malak Alzahrani, Nicholas Bertos

Clin Exp Metastasis· April 2022

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Spatially mapping the immune landscape of melanoma using imaging mass cytometry.
Dan Moldoveanu, LeeAnn Ramsay, Mathieu Lajoie, Luke Anderson-Trocme, Marine Lingrand, Nicholas R Bertos

Sci Immunol· April 2022

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Characterisation of the Stromal Microenvironment in Lobular Breast Cancer.
Laura Gómez-Cuadrado, Esme Bullock, Zeanap Mabruk, Hong Zhao, Margarita Souleimanova, Nicholas Bertos

Cancers (Basel)· February 2022

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Elevated V-ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer.
Amro H Mohammad, Sung-Hoon Kim, Nicholas Bertos, Wissal El-Assaad, Ipshita Nandi

Mol Cancer Res· October 2020

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Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors.
Paul Savage, Alain Pacis, Hellen Kuasne, Leah Liu, Daniel Lai, Nicholas R Bertos

Commun Biol· June 2020

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Primary tumors induce neutrophil extracellular traps with targetable metastasis promoting effects.
Roni F Rayes, Jack G Mouhanna, Ioana Nicolau, France Bourdeau, Betty Giannias, Nicholas Bertos

JCI Insight· July 2019

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Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers.
Tina Gruosso, Mathieu Gigoux, Venkata Satya Kumar Manem, Nicholas Bertos, Dongmei Zuo

J Clin Invest· April 2019

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CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.
Yibo Xue, Brian Meehan, Elizabeth Macdonald, Sriram Venneti, Xue Qing D Wang, Nicholas Bertos

Nat Commun· February 2019

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Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program.
Alison Hirukawa, Harvey W Smith, Dongmei Zuo, Catherine R Dufour, Paul Savage, Nicholas Bertos

Nat Commun· June 2018

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CrosstalkNet: A Visualization Tool for Differential Co-expression Networks and Communities.
Venkata Manem, George Alexandru Adam, Tina Gruosso, Mathieu Gigoux, Nicholas Bertos

Cancer Res· April 2018

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A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer.
Paul Savage, Alexis Blanchet-Cohen, Timothée Revil, Dunarel Badescu, Sadiq M I Saleh, Nicholas R Bertos

Cell Rep· October 2017

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Identification of Interacting Stromal Axes in Triple-Negative Breast Cancer.
Sadiq M I Saleh, Nicholas Bertos, Tina Gruosso, Mathieu Gigoux, Margarita Souleimanova

Cancer Res· September 2017

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Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.
Huayang Liu, James A Dowdle, Safiya Khurshid, Nicholas J Sullivan, Nicholas Bertos

Dev Cell· May 2017

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Lineage Specification from Prostate Progenitor Cells Requires Gata3-Dependent Mitotic Spindle Orientation.
Maxwell E R Shafer, Alana H T Nguyen, Mathieu Tremblay, Sophie Viala, Mélanie Béland, Nicholas R Bertos

Stem Cell Reports· April 2017

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