Publications by authors named "Nicholas Butowski"

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STELLAR: Phase III, Randomized, Open-Label Study of Eflornithine Plus Lomustine Versus Lomustine Alone in Patients With Recurrent Grade 3 Astrocytoma.
Howard Colman, Giuseppe Lombardi, Eric T Wong, Tobias Walbert, Marica Eoli, Nicholas Butowski

J Clin Oncol· December 2025

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Phase Ib/II Study of Pamiparib Plus Radiation Therapy and/or Temozolomide in Adult Patients with Treatment-Naïve or Recurrent/Refractory Glioblastoma.
Anna F Piotrowski, Kent Shih, Pierre Giglio, Howard Colman, Patrick Y Wen, Nicholas Butowski

Curr Oncol· September 2025

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Novel radiotherapy target definition using AI-driven predictions of glioblastoma recurrence from metabolic and diffusion MRI.
Nate Tran, Tracy L Luks, Yan Li, Angela Jakary, Jacob Ellison, Nicholas Butowski

NPJ Digit Med· August 2025

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A phase I study of convection-enhanced delivery (CED) of liposomal-irinotecan using real-time magnetic resonance imaging in patients with recurrent high-grade glioma.
Kazim H Narsinh, Karishma Kumar, Krystof Bankiewicz, Alastair J Martin, Mitchell Berger, Nicholas Butowski

J Neurooncol· March 2025

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Correction: Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji, Sebastian M Waszak, Stefan R Sweha, Nicholas A Butowski

Cancer Discov· March 2025

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IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma.
Jacob S Young, Nam Woo Cho, Calixto-Hope G Lucas, Hinda Najem, Kanish Mirchia, Nicholas Butowski

bioRxiv· March 2025

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Longitudinal multimodal profiling of IDH-wildtype glioblastoma reveals the molecular evolution and cellular phenotypes underlying prognostically different treatment responses.
Calixto-Hope G Lucas, Nadeem N Al-Adli, Jacob S Young, Rohit Gupta, Ramin A Morshed, Nicholas A Butowski

Neuro Oncol· January 2025

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Longitudinal profiling of IDH-mutant astrocytomas reveals acquired RAS-MAPK pathway mutations associated with inferior survival.
Eduardo Rodriguez Almaraz, Geno A Guerra, Nadeem N Al-Adli, Jacob S Young, Abraham Dada, Nicholas A Butowski

Neurooncol Adv· January 2025

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Efficacy of Adding Veliparib to Temozolomide for Patients With MGMT-Methylated Glioblastoma: A Randomized Clinical Trial.
Jann N Sarkaria, Karla V Ballman, Sani H Kizilbash, Erik P Sulman, Caterina Giannini, Nicholas A Butowski

JAMA Oncol· December 2024

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Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas.
Kwang-Soo Kim, Karl Habashy, Andrew Gould, Junfei Zhao, Hinda Najem, Nicholas Butowski

Neuro Oncol· November 2024

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NRG-BN002: Phase I study of ipilimumab, nivolumab, and the combination in patients with newly diagnosed glioblastoma.
Andrew E Sloan, Kathryn Winter, Mark R Gilbert, Kenneth Aldape, Serah Choi, Nicholas Butowski

Neuro Oncol· September 2024

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Functional prediction of response to therapy prior to therapeutic intervention is associated with improved survival in patients with high-grade glioma.
Aubrey Ledford, Analiz Rodriguez, Lindsay Lipinski, Ajay Abad, Robert Fenstermaker, Nicholas Butowski

Sci Rep· August 2024

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ONC201 (Dordaviprone) in Recurrent H3 K27M-Mutant Diffuse Midline Glioma.
Isabel Arrillaga-Romany, Sharon L Gardner, Yazmin Odia, Dolly Aguilera, Joshua E Allen, Nicholas Butowski

J Clin Oncol· May 2024

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Automatic Brain Tissue and Lesion Segmentation and Multi-Parametric Mapping of Contrast-Enhancing Gliomas without the Injection of Contrast Agents: A Preliminary Study.
Jing Liu, Angela Jakary, Javier E Villanueva-Meyer, Nicholas A Butowski, David Saloner

Cancers (Basel)· April 2024

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A systematic review of high impact CpG sites and regions for MGMT methylation in glioblastoma [A systematic review of MGMT methylation in GBM].
David Gibson, Anh Huan Vo, Hannah Lambing, Prithanjan Bhattacharya, Peggy Tahir, Nicholas Butowski

BMC Neurol· March 2024

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A combinatory vaccine with IMA950 plus varlilumab promotes effector memory T-cell differentiation in the peripheral blood of patients with low-grade gliomas.
Atsuro Saijo, Hirokazu Ogino, Nicholas A Butowski, Meghan R Tedesco, David Gibson

Neuro Oncol· February 2024

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Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses.
William C Chen, Abrar Choudhury, Mark W Youngblood, Mei-Yin C Polley, Calixto-Hope G Lucas, Nicholas Butowski

Nat Med· December 2023

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"De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
Sara Hadad, Rohit Gupta, Nancy Ann Oberheim Bush, Jennie W Taylor, Javier E Villanueva-Meyer, Nicholas A Butowski

Acta Neuropathol· December 2023

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Quantitative analysis of promoter methylation in glioblastoma suggests nonlinear prognostic effect.
David Gibson, Akshay Ravi, Eduardo Rodriguez, Susan Chang, Nancy Oberheim Bush, Nicholas A Butowski

Neurooncol Adv· September 2023

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Targeting the IL4 receptor with MDNA55 in patients with recurrent glioblastoma: Results of a phase IIb trial.
John H Sampson, Achal Singh Achrol, Manish K Aghi, Krystof Bankiewicz, Martin Bexon, Nicholas Butowski

Neuro Oncol· June 2023

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A multicenter, phase 1, dose escalation clinical trial (G-FORCE-1) of XRT, RRx-001 and temozolomide followed by temozolomide +/- RRx-001 in newly diagnosed glioblastoma.
Howard Fine, Tony Reid, Scott Caroen, Bryan Oronsky, Nacer Abrouk, Nicholas Butowski

Front Oncol· June 2023

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Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses.
David Raleigh, William Chen, Abrar Choudhury, Mark Youngblood, Mei-Yin Polley, Nicholas Butowski

Res Sq· March 2023

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NCCN Guidelines® Insights: Central Nervous System Cancers, Version 2.2022.
Craig Horbinski, Louis Burt Nabors, Jana Portnow, Joachim Baehring, Ankush Bhatia, Nicholas Butowski

J Natl Compr Canc Netw· January 2023

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Recent advances in the molecular prognostication of meningiomas.
Elaina J Wang, Alexander F Haddad, Jacob S Young, Ramin A Morshed, Joshua P H Wu, Nicholas Butowski

Front Oncol· January 2023

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