Publications by authors named "Nicholas C Denko"

Claim this Profile
D
Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer.
Ben J Haines, McKenzie Kreamer, Martin Benej, Shabber Mohammed, Haylee Bridge, Nicholas C Denko

J Med Chem· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reply to: Beyond the Score: Integrating Hypoxia Signatures Into Risk-Adapted Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer.
Nicholas J Eustace, Terence M Williams, Nicholas C Denko

JCO Precis Oncol· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Hypoxic Gene Expression Signature as a Predictor of Recurrence and Mortality in Early-Stage Non-Small Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy.
Nicholas J Eustace, Nikhil T Sebastian, Amy Webb, Konstantin Shilo, Ryan Robb, Nicholas C Denko

JCO Precis Oncol· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Epigenetic Modulation, Intra-tumoral Microbiome and Immunity in Early Onset Colorectal Cancer.
Ning Jin, Rebecca Hoyd, Ayse Selen Yilmaz, Jiangjiang Zhu, Yunzhou Liu, Nicholas C Denko

bioRxiv· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Hypoxia promotes tumor immune evasion by suppressing MHC-I expression and antigen presentation.
Hala Estephan, Arun Tailor, Robert Parker, McKenzie Kreamer, Ioanna Papandreou, Nicholas C Denko

EMBO J· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparative analysis of the tumor microbiome, molecular profiles, and immune cell abundances by HPV status in mucosal head and neck cancers and their impact on survival.
Rituraj Upadhyay, Aastha Dhakal, Caroline Wheeler, Rebecca Hoyd, Malvenderjit Jagjit Singh, Nicholas C Denko

Cancer Biol Ther· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Hypoxic adaptation of mitochondria and its impact on tumor cell function.
Martin Benej, Ioanna Papandreou, Nicholas C Denko

Semin Cancer Biol· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exogenous Sequences in Tumors and Immune Cells (Exotic): A Tool for Estimating the Microbe Abundances in Tumor RNA-seq Data.
Rebecca Hoyd, Caroline E Wheeler, YunZhou Liu, Malvenderjit S Jagjit Singh, Mitchell Muniak, Nicholas C Denko

Cancer Res Commun· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Unanticipated metabolic plasticity in response to chronic hypoxia.
Ioanna Papandreou, Martin Benej, Nicholas C Denko

Cell Metab· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Association between Tumor Microbiome and Hypoxia across Anatomic Subsites of Head and Neck Cancers.
Aastha Dhakal, Rituraj Upadhyay, Caroline Wheeler, Rebecca Hoyd, Vidhya Karivedu, Nicholas C Denko

Int J Mol Sci· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Slit2-Mediated Metabolic Reprogramming in Bone Marrow-Derived Macrophages Enhances Antitumor Immunity.
Kirti Kaul, Martin Benej, Sanjay Mishra, Dinesh K Ahirwar, Marshleen Yadav, Nicholas C Denko

Front Immunol· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth.
Nancy P Echeverri Ruiz, Vijay Mohan, Jinghai Wu, Sabina Scott, McKenzie Kreamer, Nicholas C Denko

Cancer Metab· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effect of glucose concentration and cryopreservation on mitochondrial functions of bull spermatozoa and relationship with sire conception rate.
Christa R Moraes, Luis E Moraes, Bryan Blawut, Martin Benej, Ioanna Papandreou, Nicholas C Denko

Anim Reprod Sci· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lipid droplet storage promotes murine pancreatic tumor growth.
Jeremy J Grachan, Martin Kery, Amato J Giaccia, Nicholas C Denko, Ioanna Papandreou

Oncol Rep· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors.
Martin Benej, Jinghai Wu, McKenzie Kreamer, Martin Kery, Sergio Corrales-Guerrero, Nicholas C Denko

Cancers (Basel)· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CA IX Stabilizes Intracellular pH to Maintain Metabolic Reprogramming and Proliferation in Hypoxia.
Martin Benej, Eliska Svastova, Radivojka Banova, Juraj Kopacek, Adriana Gibadulinova, Nicholas C Denko

Front Oncol· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HILPDA Regulates Lipid Metabolism, Lipid Droplet Abundance, and Response to Microenvironmental Stress in Solid Tumors.
Matthew J VandeKopple, Jinghai Wu, Erich N Auer, Amato J Giaccia, Nicholas C Denko

Mol Cancer Res· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism.
Martin Benej, Xiangqian Hong, Sandip Vibhute, Sabina Scott, Jinghai Wu, Nicholas C Denko

Proc Natl Acad Sci U S A· October 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Human Genome-Wide RNAi Screen Reveals Diverse Modulators that Mediate IRE1α-XBP1 Activation.
Zhifen Yang, Jing Zhang, Dadi Jiang, Purvesh Khatri, David E Solow-Cordero, Nicholas C Denko

Mol Cancer Res· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Urinary miRNAs as Biomarkers for Noninvasive Evaluation of Radiation-Induced Renal Tubular Injury.
Sagar Bhayana, Feifei Song, Jidhin Jacob, Paolo Fadda, Nicholas C Denko

Radiat Res· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Stress-responsive HILPDA is necessary for thermoregulation during fasting.
Matthew J VandeKopple, Jinghai Wu, Lisa A Baer, Naresh C Bal, Santosh K Maurya, Nicholas C Denko

J Endocrinol· October 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Measuring the Impact of Microenvironmental Conditions on Mitochondrial Dehydrogenase Activity in Cultured Cells.
Ramon C Sun, Albert Koong, Amato Giaccia, Nicholas C Denko

Adv Exp Med Biol· June 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.
Dadi Jiang, Arvin B Tam, Muthuraman Alagappan, Michael P Hay, Aparna Gupta, Nicholas C Denko

Mol Cancer Ther· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.
Dadi Jiang, Connor Lynch, Bruno C Medeiros, Michaela Liedtke, Rakesh Bam, Nicholas C Denko

Sci Rep· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours.
Tereza Golias, Ioanna Papandreou, Ramon Sun, Bhavna Kumar, Nicole V Brown, Nicholas C Denko

Sci Rep· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis