Publications by authors named "Nicholas Cilfone"

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Quantum processor-inspired machine learning in the biomedical sciences.
Richard Y Li, Sharvari Gujja, Sweta R Bajaj, Omar E Gamel, Nicholas Cilfone

Patterns (N Y)· June 2021

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Chronic mTOR activation induces a degradative smooth muscle cell phenotype.
Guangxin Li, Mo Wang, Alexander W Caulk, Nicholas A Cilfone, Sharvari Gujja

J Clin Invest· March 2020

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Enhancing reproducibility of gene expression analysis with known protein functional relationships: The concept of well-associated protein.
Joël R Pradines, Victor Farutin, Nicholas A Cilfone, Abouzar Ghavami, Elma Kurtagic

PLoS Comput Biol· February 2020

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Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor.
Victor Farutin, Thomas Prod'homme, Kevin McConnell, Nathaniel Washburn, Patrick Halvey, Nicholas A Cilfone

Arthritis Res Ther· October 2019

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Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis.
Pei-Yu Chen, Lingfeng Qin, Guangxin Li, Zheng Wang, James E Dahlman, Nicholas A Cilfone

Nat Metab· September 2019

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Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium.
Nicolas Ricard, Rizaldy P Scott, Carmen J Booth, Heino Velazquez, Nicholas A Cilfone

J Exp Med· August 2019

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M281, an Anti-FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First-in-Human Study.
Leona E Ling, Jan L Hillson, Renger G Tiessen, Tjerk Bosje, Mattheus Paulus van Iersel, Nicholas A Cilfone

Clin Pharmacol Ther· April 2019

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Enhancing Retrosynthetic Reaction Prediction with Deep Learning Using Multiscale Reaction Classification.
Javier L Baylon, Nicholas A Cilfone, Jeffrey R Gulcher, Thomas W Chittenden

J Chem Inf Model· February 2019

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Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology.
Joseph M Cicchese, Stephanie Evans, Caitlin Hult, Louis R Joslyn, Timothy Wessler, Nicholas A Cilfone

Immunol Rev· September 2018

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Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production.
Blanche Ip, Nicholas A Cilfone, Anna C Belkina, Jason DeFuria, Madhumita Jagannathan-Bogdan

Obesity (Silver Spring)· January 2016

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A multi-scale approach to designing therapeutics for tuberculosis.
Jennifer J Linderman, Nicholas A Cilfone, Elsje Pienaar, Chang Gong, Denise E Kirschner

Integr Biol (Camb)· May 2015

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Strategies for efficient numerical implementation of hybrid multi-scale agent-based models to describe biological systems.
Nicholas A Cilfone, Denise E Kirschner, Jennifer J Linderman

Cell Mol Bioeng· March 2015

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A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment.
Elsje Pienaar, Nicholas A Cilfone, Philana Ling Lin, Véronique Dartois, Joshua T Mattila

J Theor Biol· February 2015

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Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection.
Simeone Marino, Nicholas A Cilfone, Joshua T Mattila, Jennifer J Linderman, JoAnne L Flynn

Infect Immun· January 2015

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Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection.
Nicholas A Cilfone, Christopher B Ford, Simeone Marino, Joshua T Mattila, Hannah P Gideon

J Immunol· January 2015

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Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection.
Nicholas A Cilfone, Cory R Perry, Denise E Kirschner, Jennifer J Linderman

PLoS One· March 2014

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