Publications by authors named "Nicholas D E Greene"

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Fetal Defects in Mice Treated With Integrase Strand Transfer Inhibitors: Comparison of Dolutegravir, Raltegravir, Bictegravir, and Cabotegravir.
Haneesha Mohan, Jessica Nguyen, Audrey Yee, Evelyn Yukino Laurette, Tanvi Sanghvi, Nicholas D E Greene

J Infect Dis· October 2025

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Mitochondria protect against an intracellular pathogen by restricting access to folate.
Tânia Catarina Medeiros, Jana Ovciarikova, Xianhe Li, Patrick Krueger, Tim Bartsch, Nicholas D E Greene

Science· August 2025

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The power of mouse models in the diagnostic odyssey of patients with rare congenital anomalies.
Stephen R F Twigg, Nicholas D E Greene, Deborah J Henderson, Pleasantine Mill, Karen J Liu

Mamm Genome· June 2025

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Effect of dolutegravir-based antiretroviral therapy on glycemic control in female mice.
Valeriya Dontsova, Haneesha Mohan, Audrey Yee, Jessica Nguyen, Maisha Fahmida, Nicholas D E Greene

Sci Rep· June 2025

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DHFR2 RNA directly regulates dihydrofolate reductase and its expression level impacts folate one carbon metabolism.
Paola Drago, Niamh Bookey, Kit-Yi Leung, Michael Henry, Paula Meleady, Nicholas D E Greene

FASEB J· February 2025

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Spinal neural tube formation and tail development in human embryos.
Chloe Santos, Abigail R Marshall, Ailish Murray, Kate Metcalfe, Priyanka Narayan, Nicholas D E Greene

Elife· December 2024

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AAV-mediated expression of mouse or human GLDC normalises metabolic biomarkers in a GLDC-deficient mouse model of Non-Ketotic Hyperglycinemia.
Kit-Yi Leung, Chloe Santos, Sandra C P De Castro, Diana Gold Diaz, Andrew J Copp, Nicholas D E Greene

Mol Genet Metab· July 2024

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Association of embryonic inositol status with susceptibility to neural tube defects, metabolite profile, and maternal inositol intake.
Kit-Yi Leung, Eleanor Weston, Sandra C P De Castro, Evanthia Nikolopoulou, Sonia Sudiwala, Nicholas D E Greene

FASEB J· June 2024

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The Differential Translation Capabilities of the Human DHFR2 Gene Indicates a Developmental and Tissue-Specific Endogenous Protein of Low Abundance.
Niamh Bookey, Paola Drago, Kit-Yi Leung, Linda Hughes, Aoife MacCooey, Nicholas D E Greene

Mol Cell Proteomics· March 2024

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Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice.
Eirini Maniou, Faduma Farah, Abigail R Marshall, Zoe Crane-Smith, Andrea Krstevski, Nicholas D E Greene

Development· October 2023

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Metabolic implications and safety of dolutegravir use in pregnancy.
Valeriya Dontsova, Haneesha Mohan, Camille Blanco, Jennifer Jao, Nicholas D E Greene

Lancet HIV· September 2023

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Folate deficiency increases the incidence of dolutegravir-associated foetal defects in a mouse pregnancy model.
Haneesha Mohan, Jessica Nguyen, Ben MacKenzie, Audrey Yee, Evelyn Yukino Laurette, Nicholas D E Greene

EBioMedicine· September 2023

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A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele.
Zoe Crane-Smith, Sandra C P De Castro, Evanthia Nikolopoulou, Paul Wolujewicz, Damian Smedley, Nicholas D E Greene

Hum Mol Genet· August 2023

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Morphological phenotyping after mouse whole embryo culture.
Andrew J Copp, Maryam Clark, Nicholas D E Greene

Front Cell Dev Biol· August 2023

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The actions of methotrexate on endothelial cells are dependent on the shear stress-induced regulation of one carbon metabolism.
Marie B Lang, Kit-Yi Leung, Nicholas D E Greene, Kerri M Malone, Gaye Saginc

Front Immunol· July 2023

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The surface ectoderm exhibits spatially heterogenous tension that correlates with YAP localisation during spinal neural tube closure in mouse embryos.
Abigail R Marshall, Gabriel L Galea, Andrew J Copp, Nicholas D E Greene

Cells Dev· June 2023

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Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.
Sarah Escuin, Saba Rose Raza-Knight, Dawn Savery, Carles Gaston-Massuet, Gabriel L Galea, Nicholas D E Greene

Dis Model Mech· March 2023

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Non-Isolated Neural Tube Defects with Comorbid Malformations Are Responsive to Population-Level Folic Acid Supplementation in Northern China.
Xiaoyu Che, Jufen Liu, Gabriel L Galea, Yali Zhang, Nicholas D E Greene

Biology (Basel)· September 2022

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The arginine methyltransferase Carm1 is necessary for heart development.
Sophie Jamet, Seungshin Ha, Tzu-Hua Ho, Scott Houghtaling, Andrew Timms, Nicholas D E Greene

G3 (Bethesda)· July 2022

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and Variants in Malaysian Neural Tube Defect Families.
Siti Waheeda Mohd-Zin, Amelia Cheng Wei Tan, Wahib M Atroosh, Meow-Keong Thong, Abu Bakar Azizi, Nicholas D E Greene

Genes (Basel)· May 2022

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Two-Photon Cell and Tissue Level Laser Ablation Methods to Study Morphogenetic Biomechanics.
Abigail R Marshall, Eirini Maniou, Dale Moulding, Nicholas D E Greene, Andrew J Copp

Methods Mol Biol· February 2022

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Vangl2-environment interaction causes severe neural tube defects, without abnormal neuroepithelial convergent extension.
Oleksandr Nychyk, Gabriel L Galea, Matteo Molè, Dawn Savery, Nicholas D E Greene

Dis Model Mech· January 2022

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Dolutegravir and rat whole embryo culture.
Andrew J Copp, Nicholas D E Greene, Jennifer Jao, Rebecca Zash, Haneesha Mohan

Birth Defects Res· January 2022

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Orofacial Clefts in High Prevalence Area of Birth Defects - Five Counties, Shanxi Province, China, 2000-2020.
Jufen Liu, Yali Zhang, Le Zhang, Linlin Wang, Lei Jin, Nicholas D E Greene

China CDC Wkly· September 2021

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Passive Smoking During the Periconceptional Period and Risk for Neural Tube Defects in Offspring - Five Counties, Shanxi Province, China, 2010-2016.
Yali Zhang, Jufen Liu, Le Zhang, Lei Jin, Nicholas D E Greene

China CDC Wkly· September 2021

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