Publications by authors named "Nicholas D Walter"

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Correction: Evaluating the efficacy of HRZE-based regimens in a high-burden murine model: a back-translational assessment of rifamycins and moxifloxacin substitutions in tuberculosis treatment.
Jason E Cummings, Lisa K Woolhiser, Vincent Guglielmi, Machenzie Wernsman, Ashley Romano, Nicholas D Walter

Front Pharmacol· December 2025

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Phase 2C clinical trial of novel short-course regimens for the treatment of pulmonary tuberculosis: TBTC study 38/CRUSH-TB design.
Ekaterina V Kurbatova, Kelly E Dooley, Wendy Carr, Jason E Stout, Eric L Nuermberger, Nicholas D Walter

Contemp Clin Trials· November 2025

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Deconvoluting drug interactions using physiologic processes: transcriptional disaggregation of the BPaL regimen .
Elizabeth A Wynn, Christian Dide-Agossou, Reem Al Mubarak, Karen Rossmassler, Jo Hendrix, Nicholas D Walter

Antimicrob Agents Chemother· November 2025

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Evaluating the efficacy of HRZE-based regimens in a high-burden murine model: a back-translational assessment of rifamycins and moxifloxacin substitutions in tuberculosis treatment.
Jason E Cummings, Lisa K Woolhiser, Vincent Guglielmi, Machenzie Wernsman, Ashley Romano, Nicholas D Walter

Front Pharmacol· October 2025

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Study protocol for a duration-randomized clinical trial to determine the optimal length of treatment for multidrug-resistant tuberculosis with a 5-drug regimen: The DRAMATIC trial.
Pawandeep Kaur, Lelia H Chaisson, Zana Wangari Kiragu, Praewpannarai Buddadhumaruk, Ariana F Austin, Nicholas D Walter

Contemp Clin Trials· May 2025

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70% ethanol preserves mycobacterial RNA from cultures more efficiently than GTC-TCEP.
Lena Krausser, Magalie Van Dyck-Lippens, Ramata Balde, Rabab Reenaers, Reem Al Mubarak, Nicholas D Walter

Sci Rep· April 2025

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Emergence of antibiotic-specific phenotypes during prolonged treatment of mice.
Elizabeth A Wynn, Christian Dide-Agossou, Reem Al Mubarak, Karen Rossmassler, Victoria Ektnitphong, Nicholas D Walter

Antimicrob Agents Chemother· February 2025

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Emergence of antibiotic-specific phenotypes during prolonged treatment of mice.
Elizabeth A Wynn, Christian Dide-Agossou, Reem Al Mubarak, Karen Rossmassler, Victoria Ektnitphong, Nicholas D Walter

bioRxiv· August 2024

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Transcriptional adaptation of that survives prolonged multi-drug treatment in mice.
Elizabeth A Wynn, Christian Dide-Agossou, Matthew Reichlen, Karen Rossmassler, Reem Al Mubarak, Nicholas D Walter

mBio· December 2023

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Lung microenvironments harbor phenotypes with distinct treatment responses.
Nicholas D Walter, Jackie P Ernest, Christian Dide-Agossou, Allison A Bauman, Michelle E Ramey

Antimicrob Agents Chemother· September 2023

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Transcriptional adaptation of drug-tolerant in mice.
Elizabeth A Wynn, Christian Dide-Agossou, Matthew Reichlen, Karen Rossmassler, Reem Al Mubarak, Nicholas D Walter

bioRxiv· March 2023

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Standardized RS Ratio Metrics To Assess Tuberculosis Antimicrobial Efficacy and Potency.
Matthew J Reichlen, Sarah E M Born, Michael A Lyons, Karen Rossmassler, Justin Reid, Nicholas D Walter

Antimicrob Agents Chemother· January 2023

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MOVER approximated CV: A tool for quantifying precision in ratiometric droplet digital PCR assays.
Christian Dide-Agossou, Karen Rossmassler, Justin Reid, Juhi Purohit, Rada M Savic, Nicholas D Walter

J Pharm Biomed Anal· April 2022

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Combination of Mycobacterium tuberculosis RS Ratio and CFU Improves the Ability of Murine Efficacy Experiments to Distinguish between Drug Treatments.
Christian Dide-Agossou, Allison A Bauman, Michelle E Ramey, Karen Rossmassler, Reem Al Mubarak, Nicholas D Walter

Antimicrob Agents Chemother· April 2022

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Reproducibility of the Ribosomal RNA Synthesis Ratio in Sputum and Association with Markers of Mycobacterium tuberculosis Burden.
Emmanuel Musisi, Christian Dide-Agossou, Reem Al Mubarak, Karen Rossmassler, Abdul Wahab Ssesolo, Nicholas D Walter

Microbiol Spectr· October 2021

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Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens.
Nicholas D Walter, Sarah E M Born, Gregory T Robertson, Matthew Reichlen, Christian Dide-Agossou

Nat Commun· May 2021

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C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study.
Amanda J Meyer, Emmanuel Ochom, Patricia Turimumahoro, Patrick Byanyima, Ingvar Sanyu, Nicholas D Walter

J Clin Microbiol· December 2020

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Antibiotic Lethality and Membrane Bioenergetics.
Martin I Voskuil, Christopher R Covey, Nicholas D Walter

Adv Microb Physiol· August 2019

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Effect of anti-retroviral therapy on oxidative stress in hospitalized HIV-infected adults with and without TB.
Emmanuel Musisi, Denis Kasozi Matovu, Andrew Bukenya, Sylvia Kaswabuli, Josephine Zawedde, Nicholas D Walter

Afr Health Sci· September 2018

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Does discovery of differentially culturable M tuberculosis really demand a new treatment paradigm? Longitudinal analysis of DNA clearance from sputum.
Nicholas D Walter, Camille M Moore, Xavier A Kayigire, Christian Dide-Agossou, William Worodria

BMC Infect Dis· July 2018

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Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum.
Boatema Ofori-Anyinam, Gregory Dolganov, Tran Van, J Lucian Davis, Nicholas D Walter

Tuberculosis (Edinb)· May 2017

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Complete Genome Sequence of subsp. Strain H87 Isolated from an Indoor Water Sample.
Xueyan Zhao, L Elaine Epperson, Nabeeh A Hasan, Jennifer R Honda, Edward D Chan, Nicholas D Walter

Genome Announc· April 2017

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Treatment of Non-Tuberculous Mycobacterial Lung Disease.
Julie V Philley, Mary Ann DeGroote, Jennifer R Honda, Michael M Chan, Shannon Kasperbauer, Nicholas D Walter

Curr Treat Options Infect Dis· December 2016

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Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients.
Nicholas D Walter, Bouke C de Jong, Benjamin J Garcia, Gregory M Dolganov, William Worodria

J Infect Dis· October 2016

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Sputum is a surrogate for bronchoalveolar lavage for monitoring Mycobacterium tuberculosis transcriptional profiles in TB patients.
Benjamin J Garcia, Andre G Loxton, Gregory M Dolganov, Tran T Van, J Lucian Davis, Nicholas D Walter

Tuberculosis (Edinb)· September 2016

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