Publications by authors named "Nicholas Downing"

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PRC2/FOXO1-Mediated Repression Determines Interchangeability of ETS Oncogenes in Prostate Cancer and Ewing Sarcoma.
Nicholas F Downing, Kaitlyn M Mills, Peter C Hollenhorst

Mol Cancer Res· September 2025

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Amyloidogenesis promotes HSF1 activity enhancing cell survival during breast cancer metastatic colonization.
Natasha Hockaden, Gabi Leriger, John Wang, Haimanti Ray, Sunandan Chakrabarti, Nicholas Downing

Cell Stress Chaperones· May 2025

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A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells.
Benjamin M Greulich, Saranya Rajendran, Nicholas F Downing, Taylor R Nicholas, Peter C Hollenhorst

J Biol Chem· December 2023

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Articular cartilage and soft tissue damage from radiofrequency thermal ablation wands at wrist arthroscopy.
Grey Giddins, David Shewring, Nicholas Downing

J Hand Surg Eur Vol· July 2021

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Characteristics of Clinical Studies Used for US Food and Drug Administration Supplemental Indication Approvals of Drugs and Biologics, 2017 to 2019.
Meera Dhodapkar, Audrey D Zhang, Jeremy Puthumana, Nicholas S Downing, Nilay D Shah

JAMA Netw Open· June 2021

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Sensitivity and Specificity of Radiographs in the Diagnosis of Little and/or Ring Carpometacarpal Joint Injuries.
Sami Hassan, Abdul Aziz, Nicholas D Downing, Ryan W Trickett

J Hand Microsurg· April 2021

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Assessment of Clinical Trials Supporting US Food and Drug Administration Approval of Novel Therapeutic Agents, 1995-2017.
Audrey D Zhang, Jeremy Puthumana, Nicholas S Downing, Nilay D Shah, Harlan M Krumholz

JAMA Netw Open· April 2020

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Use of intravenous magnesium sulfate among patients with acute myocardial infarction in China from 2001 to 2015: China PEACE-Retrospective AMI Study.
Xianqiang Wang, Xue Du, Hao Yang, Emily Bucholz, Nicholas Downing

BMJ Open· March 2020

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Identification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center.
Lauren A Eberly, Aaron Richterman, Anne G Beckett, Bram Wispelwey, Regan H Marsh, Nicholas Downing

Circ Heart Fail· November 2019

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Factors Associated With Postmarketing Research for Approved Indications for Novel Medicines Approved by Both the FDA and EMA Between 2005 and 2010: A Multivariable Analysis.
Jean-David Zeitoun, Joseph S Ross, Ignacio Atal, Alexandre Vivot, Nicholas S Downing

Clin Pharmacol Ther· November 2018

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Complements from the Lung.
Nicholas S Downing, Ciaran J McMullan, Helmut G Rennke, Bruce D Levy, Joseph Loscalzo

N Engl J Med· November 2018

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Association of Racial and Socioeconomic Disparities With Outcomes Among Patients Hospitalized With Acute Myocardial Infarction, Heart Failure, and Pneumonia: An Analysis of Within- and Between-Hospital Variation.
Nicholas S Downing, Changqin Wang, Aakriti Gupta, Yongfei Wang, Sudhakar V Nuti

JAMA Netw Open· September 2018

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New and incremental FDA black box warnings from 2008 to 2015.
Michael T Solotke, Sanket S Dhruva, Nicholas S Downing, Nilay D Shah, Joseph S Ross

Expert Opin Drug Saf· February 2018

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Post-marketing research and its outcome for novel anticancer agents approved by both the FDA and EMA between 2005 and 2010: A cross-sectional study.
Jean-David Zeitoun, Gabriel Baron, Alexandre Vivot, Ignacio Atal, Nicholas S Downing

Int J Cancer· January 2018

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Postmarketing studies for novel drugs approved by both the FDA and EMA between 2005 and 2010: a cross-sectional study.
Jean-David Zeitoun, Joseph S Ross, Ignacio Atal, Alexandre Vivot, Nicholas S Downing

BMJ Open· December 2017

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Urban-Rural Comparisons in Hospital Admission, Treatments, and Outcomes for ST-Segment-Elevation Myocardial Infarction in China From 2001 to 2011: A Retrospective Analysis From the China PEACE Study (Patient-Centered Evaluative Assessment of Cardiac Events).
Xi Li, Karthik Murugiah, Jing Li, Frederick A Masoudi, Paul S Chan, Nicholas S Downing

Circ Cardiovasc Qual Outcomes· November 2017

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Are non-ST-segment elevation myocardial infarctions missing in China?
Karthik Murugiah, Yongfei Wang, Sudhakar V Nuti, Xi Li, Jing Li, Nicholas S Downing

Eur Heart J Qual Care Clin Outcomes· October 2017

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Describing the performance of U.S. hospitals by applying big data analytics.
Nicholas S Downing, Alexander Cloninger, Arjun K Venkatesh, Angela Hsieh, Elizabeth E Drye

PLoS One· September 2017

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Characteristics of Novel Therapeutics and Postmarket Safety Events-Reply.
Nicholas S Downing, Nilay D Shah, Joseph S Ross

JAMA· September 2017

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Trans-scaphoid perilunate fracture dislocation: 'notjust a scaphoid fracture'.
Clare H Rowan, Nicholas D Downing

BMJ Case Rep· July 2017

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Quality of Care in Chinese Hospitals: Processes and Outcomes After ST-segment Elevation Myocardial Infarction.
Nicholas S Downing, Yongfei Wang, Kumar Dharmarajan, Sudhakar V Nuti, Karthik Murugiah

J Am Heart Assoc· June 2017

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Regulatory Review of New Therapeutic Agents.
Nicholas S Downing, Audrey D Zhang, Joseph S Ross

N Engl J Med· June 2017

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Postapproval studies of drugs initially approved by the FDA on the basis of limited evidence: systematic review.
Alison M Pease, Harlan M Krumholz, Nicholas S Downing, Jenerius A Aminawung, Nilay D Shah

BMJ· May 2017

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Postmarket Safety Events Among Novel Therapeutics Approved by the US Food and Drug Administration Between 2001 and 2010.
Nicholas S Downing, Nilay D Shah, Jenerius A Aminawung, Alison M Pease, Jean-David Zeitoun

JAMA· May 2017

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Ischaemic heart disease in China: the time to address rising mortality rates.
Nicholas S Downing, Jing Li

Eur Heart J Qual Care Clin Outcomes· January 2017

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