Publications by authors named "Nicholas Durham"

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IL-12 encoding oNDV synergizes with CAR-T cells in orthotopic models of non-small cell lung cancer.
Amanda Rosewell Shaw, Daisuke Morita, Caroline E Porter, Eric Tu, Greyson W Biegert, Nicholas Durham

Mol Ther Oncol· December 2024

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Phase I study of a recombinant attenuated oncolytic virus, MEDI5395 (NDV-GM-CSF), administered systemically in combination with durvalumab in patients with advanced solid tumors.
Diwakar Davar, Benedito A Carneiro, Grace K Dy, Siddharth Sheth, Mitesh J Borad, Nicholas Durham

J Immunother Cancer· November 2024

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Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12.
Cheyne Kurokawa, Sonia Agrawal, Abhisek Mitra, Elena Galvani, Shannon Burke, Nicholas M Durham

Mol Ther Oncol· March 2024

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Safety and Efficacy of MEDI0457 plus Durvalumab in Patients with Human Papillomavirus-Associated Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma.
Charu Aggarwal, Nabil F Saba, Alain Algazi, Ammar Sukari, Tanguy Y Seiwert, Nicholas M Durham

Clin Cancer Res· February 2023

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Circulating Immune Cell and Outcome Analysis from the Phase II Study of PD-L1 Blockade with Durvalumab for Newly Diagnosed and Recurrent Glioblastoma.
Lakshmi Nayak, Nathan Standifer, Jorg Dietrich, Jennifer L Clarke, Gavin P Dunn, Nicholas M Durham

Clin Cancer Res· June 2022

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AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein-specific T1 response with a diverse TCR repertoire.
Phillip A Swanson, Marcelino Padilla, Wesley Hoyland, Kelly McGlinchey, Paul A Fields, Nicholas M Durham

Sci Transl Med· November 2021

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Recombinant Newcastle Disease Virus Immunotherapy Drives Oncolytic Effects and Durable Systemic Antitumor Immunity.
James Harper, Shannon Burke, Jon Travers, Nicola Rath, Andrew Leinster, Nicholas M Durham

Mol Cancer Ther· September 2021

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T-cell mediated immunity after AZD1222 vaccination: A polyfunctional spike-specific Th1 response with a diverse TCR repertoire.
Phillip A Swanson, Marcelino Padilla, Wesley Hoyland, Kelly McGlinchey, Paul A Fields, Nicholas M Durham

medRxiv· July 2021

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A New Pipeline to Predict and Confirm Tumor Neoantigens Predict Better Response to Immune Checkpoint Blockade.
Yelena Lazdun, Han Si, Todd Creasy, Koustubh Ranade, Brandon W Higgs, Nicholas M Durham

Mol Cancer Res· March 2021

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Safety and Clinical Activity of MEDI1873, a Novel GITR Agonist, in Advanced Solid Tumors.
Ani S Balmanoukian, Jeffrey R Infante, Raid Aljumaily, Aung Naing, Ashish V Chintakuntlawar, Nicholas Durham

Clin Cancer Res· December 2020

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Parallel single-cell optical transit dielectrophoresis cytometer.
Azita Fazelkhah, Samaneh Afshar, Nicholas Durham, Michael Butler, Elham Salimi

Electrophoresis· May 2020

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Enhanced immunotherapy by combining a vaccine with a novel murine GITR ligand fusion protein.
Y Maurice Morillon, Scott A Hammond, Nicholas M Durham, Jeffrey Schlom, John W Greiner

Oncotarget· September 2017

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Oncolytic VSV Primes Differential Responses to Immuno-oncology Therapy.
Nicholas M Durham, Kathy Mulgrew, Kelly McGlinchey, Noel R Monks, Hong Ji

Mol Ther· August 2017

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Targeting CD73 in the tumor microenvironment with MEDI9447.
Carl M Hay, Erin Sult, Qihui Huang, Kathy Mulgrew, Stacy R Fuhrmann, Nicholas M Durham

Oncoimmunology· August 2016

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Systemic Tolerance Mediated by Melanoma Brain Tumors Is Reversible by Radiotherapy and Vaccination.
Christopher M Jackson, Christina M Kochel, Christopher J Nirschl, Nicholas M Durham, Jacob Ruzevick

Clin Cancer Res· March 2016

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Doxil synergizes with cancer immunotherapies to enhance antitumor responses in syngeneic mouse models.
Jonathan Rios-Doria, Nicholas Durham, Leslie Wetzel, Raymond Rothstein, Jon Chesebrough

Neoplasia· August 2015

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Lymphocyte Activation Gene 3 (LAG-3) modulates the ability of CD4 T-cells to be suppressed in vivo.
Nicholas M Durham, Christopher J Nirschl, Christopher M Jackson, Jimmy Elias, Christina M Kochel

PLoS One· July 2015

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Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model.
Zineb Belcaid, Jillian A Phallen, Jing Zeng, Alfred P See, Dimitrios Mathios, Nicholas M Durham

PLoS One· March 2015

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A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression.
Brian W Simons, Nicholas M Durham, Tullia C Bruno, Joseph F Grosso, Anthony J Schaeffer

J Pathol· February 2015

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Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas.
Jing Zeng, Alfred P See, Jillian Phallen, Christopher M Jackson, Zineb Belcaid, Nicholas Durham

Int J Radiat Oncol Biol Phys· June 2013

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Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer.
Satoshi Wada, Christopher M Jackson, Kiyoshi Yoshimura, Hung-Rong Yen, Derese Getnet, Nicholas Durham

J Transl Med· April 2013

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Phenotypic and functional properties of Helios+ regulatory T cells.
Daniel J Zabransky, Christopher J Nirschl, Nicholas M Durham, Ben V Park, Christina M Ceccato

PLoS One· July 2012

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Anti-tumor effects of endogenous prostate cancer-specific CD8 T cells in a murine TCR transgenic model.
Tullia C Bruno, Cristin Rothwell, Joseph F Grosso, Derese Getnet, Hung Rong Yen, Nicholas M Durham

Prostate· April 2012

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A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells.
Derese Getnet, Joseph F Grosso, Monica V Goldberg, Timothy J Harris, Hung-Rong Yen, Nicholas M Durham

Mol Immunol· April 2010

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