Publications by authors named "Nicholas Hobson"

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Development of a Plasminogen Population PK model supporting prophylactic replacement therapy for Plasminogen deficient patients within the WAPPS-Hemo platform.
Pierre Chelle, Dagmar Hajducek, Karen Thibaudeau, Nicholas Hobson, Alfonso Iorio

Haemophilia· July 2024

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Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part II: Biomarkers and Trial Modeling.
Stephanie Hage, Serena Kinkade, Romuald Girard, Kelly D Flemming, Helen Kim, Nicholas Hobson

Stroke· January 2024

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Cavernous Angioma Symptomatic Hemorrhage (CASH) Trial Readiness II: Imaging Biomarkers and Trial Modeling.
Stephanie Hage, Serena Kinkade, Romuald Girard, Kelly D Flemming, Helen Kim, Nicholas Hobson

medRxiv· June 2023

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When alterations are violations: Moral outrage and punishment in response to (even minor) alterations to rituals.
Daniel H Stein, Juliana Schroeder, Nicholas M Hobson, Francesca Gino, Michael I Norton

J Pers Soc Psychol· July 2022

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Perfusion and Permeability MRI Predicts Future Cavernous Angioma Hemorrhage and Growth.
Je Yeong Sone, Nicholas Hobson, Abhinav Srinath, Sharbel G Romanos, Ying Li

J Magn Reson Imaging· May 2022

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Propranolol as therapy for cerebral cavernous malformations: a cautionary note.
Robert Shenkar, Thomas Moore, Christian Benavides, Rhonda Lightle, Matthew R Detter, Nicholas Hobson

J Transl Med· April 2022

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User-Centered Development and Testing of the Online Patient-Reported Outcomes, Burdens, and Experiences (PROBE) Survey and the myPROBE App and Integration With the Canadian Bleeding Disorder Registry: Mixed Methods Study.
Federico Germini, Victoria Borg Debono, David Page, Victoria Zuk, Alexandra Kucher, Nicholas Hobson

JMIR Hum Factors· March 2022

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Baseline Characteristics of Patients With Cavernous Angiomas With Symptomatic Hemorrhage in Multisite Trial Readiness Project.
Helen Kim, Kelly D Flemming, Jeffrey A Nelson, Avery Lui, Jennifer J Majersik, Nicholas Hobson

Stroke· December 2021

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Perfusion and permeability as diagnostic biomarkers of cavernous angioma with symptomatic hemorrhage.
Je Yeong Sone, Yan Li, Nicholas Hobson, Sharbel G Romanos, Abhinav Srinath

J Cereb Blood Flow Metab· November 2021

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Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models.
Wenqing Li, Robert Shenkar, Mathew R Detter, Thomas Moore, Christian Benavides, Nicholas Hobson

J Clin Invest· October 2021

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A sacred commitment: How rituals promote group survival.
Daniel H Stein, Nicholas M Hobson, Juliana Schroeder

Curr Opin Psychol· August 2021

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Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation.
Miguel Alejandro Lopez-Ramirez, Catherine Chinhchu Lai, Shady Ibrahim Soliman, Preston Hale, Angela Pham, Nicholas Hobson

J Clin Invest· July 2021

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PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Aileen A Ren, Daniel A Snellings, Yourong S Su, Courtney C Hong, Marco Castro, Nicholas Hobson

Nature· June 2021

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Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models.
Wenqing Li, Robert Shenkar, Mathew R Detter, Thomas Moore, Christian Benavides, Nicholas Hobson

J Clin Invest· February 2021

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A Roadmap for Developing Plasma Diagnostic and Prognostic Biomarkers of Cerebral Cavernous Angioma With Symptomatic Hemorrhage (CASH).
Romuald Girard, Yan Li, Agnieszka Stadnik, Robert Shenkar, Nicholas Hobson

Neurosurgery· February 2021

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Novel Murine Models of Cerebral Cavernous Malformations.
Matthew R Detter, Robert Shenkar, Christian R Benavides, Catherine A Neilson, Thomas Moore, Nicholas Hobson

Angiogenesis· November 2020

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Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.
Courtney C Hong, Alan T Tang, Matthew R Detter, Jaesung P Choi, Rui Wang, Nicholas Hobson

J Exp Med· October 2020

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A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
Lisa McKerracher, Robert Shenkar, Matthew Abbinanti, Ying Cao, Amy Peiper, Nicholas Hobson

Transl Stroke Res· June 2020

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Phantom validation of quantitative susceptibility and dynamic contrast-enhanced permeability MR sequences across instruments and sites.
Nicholas Hobson, Sean P Polster, Ying Cao, Kelly Flemming, Yunhong Shu

J Magn Reson Imaging· April 2020

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Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial.
Sean P Polster, Agnieszka Stadnik, Amy L Akers, Ying Cao, Gregory A Christoforidis, Nicholas Hobson

Neurosurgery· December 2019

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Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.
Alan T Tang, Katie R Sullivan, Courtney C Hong, Lauren M Goddard, Aparna Mahadevan, Nicholas Hobson

Sci Transl Med· November 2019

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Clustering superparamagnetic iron oxide nanoparticles produces organ-targeted high-contrast magnetic resonance images.
Nicholas J Hobson, Xian Weng, Bernard Siow, Catarina Veiga, Marianne Ashford

Nanomedicine (Lond)· May 2019

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Trial Readiness in Cavernous Angiomas With Symptomatic Hemorrhage (CASH).
Sean P Polster, Ying Cao, Timothy Carroll, Kelly Flemming, Romuald Girard, Nicholas Hobson

Neurosurgery· April 2019

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Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.
Robert Shenkar, Amy Peiper, Heidy Pardo, Thomas Moore, Rhonda Lightle, Nicholas Hobson

Stroke· March 2019

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