Publications by authors named "Nicholas Hurlburt"

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The N-terminal region of malaria vaccine candidate asparagine-rich merozoite antigen is immunodominant and targeted by polyreactive antibodies.
Rolando Garza, Jeffrey M Marchioni, Jared D Honeycutt, Nicholas K Hurlburt, Caroline Torres

bioRxiv· December 2025

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Human monoclonal antibodies to HPV16 show evidence for common developmental pathways and public epitopes.
Joseph J Carter, Nicholas K Hurlburt, Erin M Scherer, Suruchi Singh, Justas V Rodarte

PLoS Pathog· October 2025

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Anti-Malaria Antibody Engineering Broadens Recognition Motifs and Reveals New Homotypic Interactions that Enhance Protective Breadth.
Jihwan Chun, Prabhanshu Tripathi, Yevel Flores-Garcia, Bharat Madan, Gene A Lee, Nicholas K Hurlburt

bioRxiv· October 2025

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Structural basis for antibody cross-neutralization of Dengue and Zika viruses.
Nicholas K Hurlburt, Jay Lubow, Leslie Goo, Marie Pancera

bioRxiv· June 2025

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Elicitation of liver-stage immunity by nanoparticle immunogens displaying P. falciparum CSP-derived antigens.
Mark D Langowski, Joseph R Francica, Alex L Roederer, Nicholas K Hurlburt, Justas V Rodarte

NPJ Vaccines· May 2025

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HPV16 neutralizing monoclonal antibodies show evidence for common developmental pathways and public epitopes.
Joseph J Carter, Nicholas K Hurlburt, Erin M Scherer, Suruchi Singh, Justas V Rodarte

bioRxiv· April 2025

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Broadly inhibitory antibodies to severe malaria virulence proteins.
Raphael A Reyes, Sai Sundar Rajan Raghavan, Nicholas K Hurlburt, Viola Introini, Sebastiaan Bol

Nature· December 2024

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Short CDRL1 in intermediate VRC01-like mAbs is not sufficient to overcome key glycan barriers on HIV-1 Env.
Parul Agrawal, Maria L Knudsen, Anna MacCamy, Nicholas K Hurlburt, Arineh Khechaduri

J Virol· October 2024

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Broadly inhibitory antibodies against severe malaria virulence proteins.
Raphael A Reyes, Sai Sundar Rajan Raghavan, Nicholas K Hurlburt, Viola Introini, Ikhlaq Hussain Kana

bioRxiv· January 2024

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Highly protective antimalarial antibodies via precision library generation and yeast display screening.
Bailey B Banach, Prabhanshu Tripathi, Lais Da Silva Pereira, Jason Gorman, Thuy Duong Nguyen, Nicholas K Hurlburt

J Exp Med· August 2022

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Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit.
Nicholas K Hurlburt, Leah J Homad, Irika Sinha, Madeleine F Jennewein, Anna J MacCamy

Commun Biol· April 2022

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The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Lawrence T Wang, Nicholas K Hurlburt, Arne Schön, Barbara J Flynn, Yevel Flores-Garcia

Cell Rep· February 2022

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Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects.
Madeleine F Jennewein, Anna J MacCamy, Nicholas R Akins, Junli Feng, Leah J Homad, Nicholas K Hurlburt

Cell Rep· July 2021

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Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects.
Madeleine F Jennewein, Anna J MacCamy, Nicholas R Akins, Junli Feng, Leah J Homad, Nicholas K Hurlburt

bioRxiv· March 2021

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Design of Alphavirus Virus-Like Particles Presenting Circumsporozoite Junctional Epitopes That Elicit Protection against Malaria.
Joseph R Francica, Wei Shi, Gwo-Yu Chuang, Steven J Chen, Lais Da Silva Pereira, Nicholas Hurlburt

Vaccines (Basel)· March 2021

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Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A.
Nicholas K Hurlburt, Jasper Guan, Hoonsan Ong, Hai Yu, Xi Chen

Acta Crystallogr F Struct Biol Commun· November 2020

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A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver.
Lawrence T Wang, Lais S Pereira, Yevel Flores-Garcia, James O'Connor, Barbara J Flynn, Nicholas K Hurlburt

Immunity· October 2020

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Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation.
Nicholas K Hurlburt, Emilie Seydoux, Yu-Hsin Wan, Venkata Viswanadh Edara, Andrew B Stuart

Nat Commun· October 2020

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Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation.
Emilie Seydoux, Leah J Homad, Anna J MacCamy, K Rachael Parks, Nicholas K Hurlburt

Immunity· July 2020

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Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation.
Nicholas K Hurlburt, Yu-Hsin Wan, Andrew B Stuart, Junli Feng, Andrew T McGuire

bioRxiv· June 2020

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Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual.
Emilie Seydoux, Leah J Homad, Anna J MacCamy, K Rachael Parks, Nicholas K Hurlburt

bioRxiv· May 2020

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Structure of the Cladosporium fulvum Avr4 effector in complex with (GlcNAc)6 reveals the ligand-binding mechanism and uncouples its intrinsic function from recognition by the Cf-4 resistance protein.
Nicholas K Hurlburt, Li-Hung Chen, Ioannis Stergiopoulos, Andrew J Fisher

PLoS Pathog· August 2018

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The Receptor-like Cytoplasmic Kinase BIK1 Localizes to the Nucleus and Regulates Defense Hormone Expression during Plant Innate Immunity.
Neeraj K Lal, Ugrappa Nagalakshmi, Nicholas K Hurlburt, Rosalva Flores, Aurelie Bak

Cell Host Microbe· April 2018

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Structural Analysis of an Avr4 Effector Ortholog Offers Insight into Chitin Binding and Recognition by the Cf-4 Receptor.
Amanda C Kohler, Li-Hung Chen, Nicholas Hurlburt, Anthony Salvucci, Benjamin Schwessinger

Plant Cell· August 2016

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