Publications by authors named "Nicholas J Simmonds"

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Maximising opportunity for therapeutic success: sequential participation in cystic fibrosis nucleic acid-based therapy trials.
Nicole Mayer-Hamblett, Natanya R Kerper, John P Clancy, Jane C Davies, Jennifer L Taylor-Cousar, Nicholas J Simmonds

Lancet Respir Med· December 2025

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Beyond Cystic Fibrosis: Recognising Shwachman-Diamond Syndrome in the Respiratory Clinic.
Freda Yang, Ladina Weitnauer, Imogen Felton, Nicholas J Simmonds

Respirol Case Rep· December 2025

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Spirometry thresholds for clinical trial eligibility: time for urgent re-evaluation.
Idan Bokobza, Melanie Le Sayec, Cara Bossley, Rossa Brugha, Jane Carolyn Davies, Nicholas J Simmonds

Thorax· October 2025

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"Mind the gap"- will we ever see equal median predicted survival for males and females in cystic fibrosis?
Jamie Duckers, Sarah L Clarke, Susan C Charman, Siobhan Carr, Nicholas J Simmonds

J Cyst Fibros· September 2025

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Measurement of treatment burden in cystic fibrosis: A systematic review.
Rana Altabee, Martin J Mwamba, David Turner, Gwyneth Davies, Janice Abbott, Nicholas J Simmonds

J Cyst Fibros· May 2025

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Improving ototoxicity monitoring in patients receiving aminoglycosides using a novel digital approach: a quality improvement project.
Jamie Cheong, Shereen Boreland, Elaine Shattock, Elaine Bowman, Barbara Belkarty, Nicholas J Simmonds

BMJ Open Qual· April 2025

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Managing an ageing cystic fibrosis population: challenges and priorities.
Freddy J Frost, Daniel G Peckham, Imogen C Felton, Joanna E Snowball, Robert D Gray, Nicholas J Simmonds

Eur Respir Rev· April 2025

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Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis.
Amelia Bercusson, Thomas J Williams, Nicholas J Simmonds, Eric Wfw Alton, Uta Griesenbach

PLoS Pathog· February 2025

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Bridging the gap: Challenging lung infections and clinical trial development in cystic fibrosis.
Damian G Downey, Nicholas J Simmonds, Silke van-Koningsbruggen-Rietschel, Jutta Bend, Fiona Dunlevy

J Cyst Fibros· January 2025

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Evaluating the correspondence between the EQ-5D-5L and disease severity and quality of life in adults and adolescents with cystic fibrosis.
Rana Altabee, Siobhan B Carr, Janice Abbott, Rory Cameron, Daniel Office, Nicholas J Simmonds

Respir Med Res· November 2024

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Reversal of cystic bronchiectasis with elexacaftor/tezacaftor/ivacaftor.
Peter G Middleton, Nicholas J Simmonds

Eur Respir J· September 2024

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Inhaled antimicrobial prescribing for Pseudomonas aeruginosa infections in Europe.
Callum M Sloan, Laura J Sherrard, Gisli G Einarsson, Lieven J Dupont, Silke van Koningsbruggen-Rietschel, Nicholas J Simmonds

J Cyst Fibros· May 2024

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Why don't anti-inflammatories work in cystic fibrosis?
Michelle Casey, Nicholas J Simmonds

Expert Rev Respir Med· April 2024

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The effectiveness of CFTR modulators in people with CF and rare mutations: A real-world study.
Sofia Hanger, Imogen Felton, Emem-Fong Ukor, Elaine Bowman, Clare Caldwell, Nicholas J Simmonds

Pediatr Pulmonol· January 2024

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How representative are clinical trial cohorts of the general CF population? Implications for trial planning.
Rebecca Dobra, Sophie Pinnell, Andy Jones, Susan Madge, Nicholas J Simmonds

J Cyst Fibros· January 2024

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Standards for the care of people with cystic fibrosis (CF): A timely and accurate diagnosis.
Carlo Castellani, Nicholas J Simmonds, Jürg Barben, Charlotte Addy, Amanda Bevan

J Cyst Fibros· November 2023

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Cystic fibrosis modulator therapy can reverse cystic bronchiectasis.
Peter G Middleton, Nicholas J Simmonds

Respirol Case Rep· July 2023

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Diagnosing Cystic Fibrosis in Adults.
Peter J Barry, Nicholas J Simmonds

Semin Respir Crit Care Med· April 2023

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Response.
Rory A Cameron, Mark Rowley, Nicholas J Simmonds, Jennifer A Whitty, Siobhán B Carr

Chest· April 2023

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An invisible threat? Aspergillus positive cultures and co-infecting bacteria in airway samples.
Dominic A Hughes, Mark Rosenthal, Leah Cuthbertson, Newara Ramadan, Imogen Felton, Nicholas J Simmonds

J Cyst Fibros· March 2023

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VOCAL: An observational study of ivacaftor for people with cystic fibrosis and selected non-G551D-CFTR gating mutations.
Nicholas J Simmonds, C Kors van der Ent, Carla Colombo, Nils Kinnman, Cynthia DeSouza

J Cyst Fibros· January 2023

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Treatment Preference Among People With Cystic Fibrosis: The Importance of Reducing Treatment Burden.
Rory A Cameron, Daniel Office, Jessie Matthews, Mark Rowley, Janice Abbott, Nicholas J Simmonds

Chest· December 2022

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Assessing the health risk of living near composting facilities on lung health, fungal and bacterial disease in cystic fibrosis: a UK CF Registry study.
Muhammad Saleem Khan, Philippa Douglas, Anna L Hansell, Nicholas J Simmonds, Frédéric B Piel

Environ Health· December 2022

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Mediation of the total effect of cystic fibrosis-related diabetes on mortality: A UK Cystic Fibrosis Registry cohort study.
Kamaryn T Tanner, Rhian M Daniel, Diana Bilton, Nicholas J Simmonds, Linda D Sharples

Diabet Med· November 2022

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Clinimetric analysis of outcome measures for airway clearance in people with cystic fibrosis: a systematic review.
Gemma E Stanford, Mandy Jones, Susan C Charman, Diana Bilton, Omar S Usmani, Nicholas J Simmonds

Ther Adv Respir Dis· September 2022

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