Publications by authors named "Nicholas Lea"

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Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses.
Lei Jin, Heather A Sullivan, Mulangma Zhu, Thomas K Lavin, Makoto Matsuyama, Nicholas E Lea

Nat Neurosci· February 2024

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Publisher Correction: Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses.
Lei Jin, Heather A Sullivan, Mulangma Zhu, Thomas K Lavin, Makoto Matsuyama, Nicholas E Lea

Nat Neurosci· February 2024

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Third-generation rabies viral vectors allow nontoxic retrograde targeting of projection neurons with greatly increased efficiency.
Lei Jin, Heather A Sullivan, Mulangma Zhu, Nicholas E Lea, Thomas K Lavin

Cell Rep Methods· November 2023

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"Self-inactivating" rabies viruses are susceptible to loss of their intended attenuating modification.
Lei Jin, Makoto Matsuyama, Heather A Sullivan, Mulangma Zhu, Thomas K Lavin, Nicholas E Lea

Proc Natl Acad Sci U S A· February 2023

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Targeting thalamic circuits rescues motor and mood deficits in PD mice.
Ying Zhang, Dheeraj S Roy, Yi Zhu, Yefei Chen, Tomomi Aida, Nicholas E Lea

Nature· July 2022

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Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models.
Dheeraj S Roy, Ying Zhang, Tomomi Aida, Soonwook Choi, Qian Chen, Nicholas E Lea

Neuron· August 2021

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Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes.
Terry J Gaymes, Sydney Shall, Lee J Macpherson, Natalie A Twine, Nicholas C Lea

Haematologica· August 2021

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Impact of somatic mutations in myelodysplastic patients with isolated partial or total loss of chromosome 7.
Elena Crisà, Austin G Kulasekararaj, Vera Adema, Esperanza Such, Julie Schanz, Nicholas Lea

Leukemia· September 2020

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Monosynaptic Tracing Success Depends Critically on Helper Virus Concentrations.
Thomas K Lavin, Lei Jin, Nicholas E Lea, Ian R Wickersham

Front Synaptic Neurosci· February 2020

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Effect of low-level BCR-ABL1 kinase domain mutations identified by next-generation sequencing in patients with chronic myeloid leukaemia: a population-based study.
Aytug Kizilors, Elena Crisà, Nicholas Lea, Roberto Passera, Syed Mian

Lancet Haematol· May 2019

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GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML.
Ahad F Al Seraihi, Ana Rio-Machin, Kiran Tawana, Csaba Bödör, Jun Wang, Nicholas Lea

Leukemia· November 2018

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Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells.
Pedro Casado, Edmund H Wilkes, Farideh Miraki-Moud, Marym Mohammad Hadi, Ana Rio-Machin, Nicholas Lea

Leukemia· August 2018

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Nontoxic, double-deletion-mutant rabies viral vectors for retrograde targeting of projection neurons.
Soumya Chatterjee, Heather A Sullivan, Bryan J MacLennan, Ran Xu, YuanYuan Hou, Nicholas E Lea

Nat Neurosci· April 2018

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Heterozygous variants in bone marrow failure and myeloid neoplasms.
Judith C W Marsh, Fernanda Gutierrez-Rodrigues, James Cooper, Jie Jiang, Shreyans Gandhi, Nicholas Lea

Blood Adv· January 2018

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Behavior of the Tandem Glycine Riboswitch in .
Arianne M Babina, Nicholas E Lea, Michelle M Meyer

mBio· October 2017

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Mixed T Cell Chimerism After Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia Using an Alemtuzumab-Containing Regimen Is Shaped by Persistence of Recipient CD8 T Cells.
Francesco Grimaldi, Victoria Potter, Pilar Perez-Abellan, John P Veluchamy, Muhammad Atif, Nicholas Lea

Biol Blood Marrow Transplant· February 2017

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Baseline cytokine profiling identifies novel risk factors for invasive fungal disease among haematology patients undergoing intensive chemotherapy or haematopoietic stem cell transplantation.
M Mansour Ceesay, Shahram Kordasti, Eamaan Rufaie, Nicholas Lea, Melvyn Smith

J Infect· September 2016

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Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome.
Syed A Mian, Alexander E Smith, Austin G Kulasekararaj, Aytug Kizilors, Azim M Mohamedali, Nicholas C Lea

Haematologica· July 2013

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TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis.
Austin G Kulasekararaj, Alexander E Smith, Syed A Mian, Azim M Mohamedali, Pramila Krishnamurthy, Nicholas C Lea

Br J Haematol· March 2013

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Prevalence and clinical outcomes of the 46/1 haplotype, Janus kinase 2 mutations, and ten-eleven translocation 2 mutations in Budd-Chiari syndrome and their impact on thrombotic complications post liver transplantation.
Rachel H Westbrook, Nicholas C Lea, Azim M Mohamedali, Alexander E Smith, David W Orr

Liver Transpl· July 2012

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Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry.
Stephen J Orr, Daniel R Boutz, Rong Wang, Constantinos Chronis, Nicholas C Lea

Mol Syst Biol· March 2012

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Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value.
Alexander E Smith, Azim M Mohamedali, Austin Kulasekararaj, ZiYi Lim, Joop Gäken, Nicholas C Lea

Blood· November 2010

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Novel TET2 mutations associated with UPD4q24 in myelodysplastic syndrome.
Azim M Mohamedali, Alexander E Smith, Joop Gaken, Nicholas C Lea, Syed A Mian

J Clin Oncol· August 2009

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Epigenetics of human T cells during the G0-->G1 transition.
Alexander E Smith, Constantinos Chronis, Manolis Christodoulakis, Stephen J Orr, Nicholas C Lea

Genome Res· August 2009

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Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes.
Terry J Gaymes, Sydney Shall, Lee J MacPherson, Natalie A Twine, Nicholas C Lea

Haematologica· May 2009

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