Publications by authors named "Nicholas Lemoine"

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Correction: Yan et al. Oncolytic Vaccinia Virus Armed with GM-CSF and IL-7 Enhances Antitumor Immunity in Pancreatic Cancer. 2025, , 882.
Wenyi Yan, Yujing Xuan, Ruimin Wang, Ziyan Huan, Yu Guo, Nicholas Robert Lemoine

Biomedicines· August 2025

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GM-CSF and IL-21-armed oncolytic vaccinia virus significantly enhances anti-tumor activity and synergizes with anti-PD1 immunotherapy in pancreatic cancer.
Yujing Xuan, Wenyi Yan, Ruimin Wang, Xibin Wang, Yu Guo, Nicholas R Lemoine

Front Immunol· May 2025

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A novel oncolytic Vaccinia virus armed with IL-12 augments antitumor immune responses leading to durable regression in murine models of lung cancer.
Lijuan Chen, Pengju Wang, Carmela Di Gioia, Ming Yuan, Zhe Zhang, Nicholas R Lemoine

Front Immunol· May 2025

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Novel oncolytic vaccinia virus armed with interleukin-27 is a potential therapeutic agent for the treatment of murine pancreatic cancer.
Yangyang Jia, Yanru Wang, Guanghao Zhao, Yong Yang, Wenyi Yan, Nicholas R Lemoine

J Immunother Cancer· May 2025

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FBL promotes hepatocellular carcinoma tumorigenesis and progression by recruiting YY1 to enhance CAD gene expression.
Yafei Zhi, Yan Guo, Shiliang Li, Xinyu He, Huifang Wei, Nicholas R Lemoine

Cell Death Dis· April 2025

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Oncolytic Vaccinia Virus Armed with GM-CSF and IL-7 Enhances Antitumor Immunity in Pancreatic Cancer.
Wenyi Yan, Yujing Xuan, Ruimin Wang, Ziyan Huan, Yu Guo, Nicholas Robert Lemoine

Biomedicines· April 2025

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The Combination of Oncolytic Virus and Antibody Blockade of TGF-β Enhances the Efficacy of αvβ6-Targeting CAR T Cells Against Pancreatic Cancer in an Immunocompetent Model.
Zuoyi Zhao, Lauren C Cutmore, Renato B Baleeiro, Joseph J Hartlebury, Nicholas Brown, Nicholas Lemoine

Cancers (Basel)· April 2025

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Genomic-transcriptomic analysis identifies the Syrian hamster as a superior animal model for human diseases.
Chuchu Wang, Zhenguo Cheng, Jinxin Miao, Xia Xue, Yunshu Dong, Nicholas R Lemoine

BMC Genomics· March 2025

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The integrated molecular and histological analysis defines subtypes of esophageal squamous cell carcinoma.
Guozhong Jiang, Zhizhong Wang, Zhenguo Cheng, Weiwei Wang, Shuangshuang Lu, Nicholas R Lemoine

Nat Commun· October 2024

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Oncolytic vaccinia virus and cancer immunotherapy.
Lihua Xu, Huihui Sun, Nicholas R Lemoine, Yujing Xuan, Pengju Wang

Front Immunol· January 2024

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The capability of heterogeneous γδ T cells in cancer treatment.
Wenyi Yan, Louisa S Chard Dunmall, Nicholas R Lemoine, Yaohe Wang, Yafeng Wang

Front Immunol· December 2023

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Hypoxia-regulated secretion of IL-12 enhances antitumor activity and safety of CD19 CAR-T cells in the treatment of DLBCL.
Wenping Zhou, Jinxin Miao, Zhenguo Cheng, Zhimin Wang, Jianyao Wang, Nicholas R Lemoine

Mol Ther Oncolytics· September 2023

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A novel microenvironment regulated system CAR-T (MRS.CAR-T) for immunotherapeutic treatment of esophageal squamous carcinoma.
Lihong Wang, Xiaosa Wang, Yangyang Wu, Jingjing Wang, Wenping Zhou, Nicholas R Lemoine

Cancer Lett· August 2023

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Personalized neoantigen viro-immunotherapy platform for triple-negative breast cancer.
Renato Brito Baleeiro, Peng Liu, Louisa S Chard Dunmall, Carmela Di Gioia, Ai Nagano, Nicholas Lemoine

J Immunother Cancer· August 2023

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Syrian hamster as an ideal animal model for evaluation of cancer immunotherapy.
Yangyang Jia, Yanru Wang, Louisa S Chard Dunmall, Nicholas R Lemoine, Pengju Wang

Front Immunol· March 2023

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Modification of the Early Gene Enhancer-promoter Improves the Oncolytic Potency of Adenovirus 11.
Han Hsi Wong, Guozhong Jiang, Rathi Gangeswaran, Pengju Wang, Jiwei Wang, Nicholas R Lemoine

Mol Ther· January 2023

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An effective therapeutic regime for treatment of glioma using oncolytic vaccinia virus expressing IL-21 in combination with immune checkpoint inhibition.
Yijie Sun, Zhe Zhang, Chenglin Zhang, Na Zhang, Pengju Wang, Nicholas R Lemoine

Mol Ther Oncolytics· September 2022

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Redirecting anti-Vaccinia virus T cell immunity for cancer treatment by AAV-mediated delivery of the VV B8R gene.
Dujuan Cao, Qianqian Song, Junqi Li, Louisa S Chard Dunmall, Yuanyuan Jiang, Nicholas R Lemoine

Mol Ther Oncolytics· June 2022

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MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy.
Renato B Baleeiro, Christian J Bouwens, Peng Liu, Carmela Di Gioia, Louisa S Chard Dunmall, Nicholas R Lemoine

Oncoimmunology· June 2022

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Optimized Anchor-Modified Peptides Targeting Mutated RAS Are Promising Candidates for Immunotherapy.
Renato B Baleeiro, Louisa S Chard Dunmall, Peng Liu, Shuangshuang Lu, Yuchun Lone, Nicholas R Lemoine

Front Immunol· June 2022

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CEACAM7 Is an Effective Target for CAR T-cell Therapy of Pancreatic Ductal Adenocarcinoma.
Deepak Raj, Maria Nikolaidi, Irene Garces, Daniela Lorizio, Natalia M Castro, Nicholas R Lemoine

Clin Cancer Res· March 2021

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A systemically deliverable Vaccinia virus with increased capacity for intertumoral and intratumoral spread effectively treats pancreatic cancer.
Giulia Marelli, Louisa S Chard Dunmall, Ming Yuan, Carmela Di Gioia, Jinxin Miao, Nicholas Lemoine

J Immunother Cancer· January 2021

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A Tumor-Targeted Replicating Oncolytic Adenovirus Ad-TD-nsIL12 as a Promising Therapeutic Agent for Human Esophageal Squamous Cell Carcinoma.
Zifang Zhang, Chunyang Zhang, Jinxin Miao, Zhizhong Wang, Zhimin Wang, Nicholas R Lemoine

Cells· November 2020

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Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer.
Emanuela Gadaleta, Pauline Fourgoux, Stefano Pirró, Graeme J Thorn, Rachel Nelan, Nicholas R Lemoine

NPJ Breast Cancer· August 2020

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SNPnexus: a web server for functional annotation of human genome sequence variation (2020 update).
Jorge Oscanoa, Lavanya Sivapalan, Emanuela Gadaleta, Abu Z Dayem Ullah, Nicholas R Lemoine

Nucleic Acids Res· July 2020

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