Publications by authors named "Nicholas Lyle"

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Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of profilin-1.
Marc I Diamond, Shirong Cai, Aaron Boudreau, Clifton J Carey, Nicholas Lyle

J Biol Chem· April 2015

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Quantitative assessments of the distinct contributions of polypeptide backbone amides versus side chain groups to chain expansion via chemical denaturation.
Alex S Holehouse, Kanchan Garai, Nicholas Lyle, Andreas Vitalis, Rohit V Pappu

J Am Chem Soc· March 2015

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Hamiltonian Switch Metropolis Monte Carlo Simulations for Improved Conformational Sampling of Intrinsically Disordered Regions Tethered to Ordered Domains of Proteins.
Anuradha Mittal, Nicholas Lyle, Tyler S Harmon, Rohit V Pappu

J Chem Theory Comput· August 2014

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Denatured state ensembles with the same radii of gyration can form significantly different long-range contacts.
Bowu Luan, Nicholas Lyle, Rohit V Pappu, Daniel P Raleigh

Biochemistry· January 2014

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A quantitative measure for protein conformational heterogeneity.
Nicholas Lyle, Rahul K Das, Rohit V Pappu

J Chem Phys· September 2013

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The denatured state ensemble contains significant local and long-range structure under native conditions: analysis of the N-terminal domain of ribosomal protein L9.
Wenli Meng, Bowu Luan, Nicholas Lyle, Rohit V Pappu, Daniel P Raleigh

Biochemistry· April 2013

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Experiments and simulations show how long-range contacts can form in expanded unfolded proteins with negligible secondary structure.
Wenli Meng, Nicholas Lyle, Bowu Luan, Daniel P Raleigh, Rohit V Pappu

Proc Natl Acad Sci U S A· February 2013

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Describing sequence-ensemble relationships for intrinsically disordered proteins.
Albert H Mao, Nicholas Lyle, Rohit V Pappu

Biochem J· January 2013

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Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins.
Randal Halfmann, Simon Alberti, Rajaraman Krishnan, Nicholas Lyle, Charles W O'Donnell

Mol Cell· July 2011

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Thermodynamics of beta-sheet formation in polyglutamine.
Andreas Vitalis, Nicholas Lyle, Rohit V Pappu

Biophys J· July 2009

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