Publications by authors named "Nicholas Lynch"

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Spectroscopic Manifestations of (Anti)Aromaticity in Oxidized and Reduced Porphyrin and Norcorrole.
Stephen D S Bortolussi, Carmen Zhou, Nicholas B Lynch, Martin D Peeks

Chemistry· August 2024

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Fragment-based drug discovery for disorders of the central nervous system: designing better drugs piece by piece.
Bill W G L Chan, Nicholas B Lynch, Wendy Tran, Jack M Joyce, G Paul Savage

Front Chem· April 2024

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Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection.
Youssif M Ali, George W Carnell, Stefano Fumagalli, Domenico Mercurio, Serena Seminara, Nicholas J Lynch

J Infect Dis· March 2024

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Clear aligner therapy in the mixed dentition: Indications and practitioner perspectives.
Nicholas M Lynch, Bhavna Shroff, Caroline K Carrico, Vincent Sawicki, Morgan Sabol

Am J Orthod Dentofacial Orthop· August 2023

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Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice.
Youssif M Ali, Nicholas J Lynch, Ahmed A Shaaban, Dina E Rizk, Shaymaa H Abdel-Rahman

Front Immunol· June 2023

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Camera-based radiotherapy dosimetry using dual-material 3D printed scintillator arrays.
Nicholas Lynch, James L Robar, Thalat Monajemi

Med Phys· March 2023

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Unbuilding the city: Deconstruction and the circular economy in Vancouver.
Nicholas Lynch

Environ Plan A· November 2022

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Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID-19.
Nicholas J Lynch, Andrew C Y Chan, Youssif M Ali, Priyanka Khatri, Ifeoluwa E Bamigbola

Clin Transl Med· July 2022

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Secondary Complement Deficiency Impairs Anti-Microbial Immunity to and During Severe Acute COVID-19.
Youssif M Ali, Nicholas J Lynch, Priyanka Khatri, Ifeoluwa E Bamigbola, Andrew C Y Chan

Front Immunol· May 2022

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Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins.
Youssif M Ali, Matteo Ferrari, Nicholas J Lynch, Sadam Yaseen, Thomas Dudler

Front Immunol· August 2021

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Characterization of novel 3D printed plastic scintillation dosimeters.
Nicholas Lynch, Thalat Monajemi, James L Robar

Biomed Phys Eng Express· September 2020

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The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface.
Kashif S Haleem, Youssif M Ali, Hasan Yesilkaya, Thomas Kohler, Sven Hammerschmidt, Nicholas J Lynch

Infect Immun· January 2019

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In vitro characterization of gamma oscillations in the hippocampal formation of the domestic chick.
Pradeep Dheerendra, Nicholas M Lynch, Joseph Crutwell, Mark O Cunningham, Tom V Smulders

Eur J Neurosci· October 2018

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Endoscopically Assisted Modified Caldwell-Luc Approach to Enucleation of Dentigerous Cyst With Ectopic Tooth From the Maxillary Sinus.
Isaac Liau, Nicholas Lynch, Brenton Hearn, Andrew Cheng

J Craniofac Surg· September 2018

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Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
Sadam Yaseen, Gregory Demopulos, Thomas Dudler, Munehisa Yabuki, Christi L Wood, Nicholas Lynch

FASEB J· May 2017

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Requirement of Neuronal Ribosome Synthesis for Growth and Maintenance of the Dendritic Tree.
Lukasz P Slomnicki, Maciej Pietrzak, Aruna Vashishta, James Jones, Nicholas Lynch

J Biol Chem· March 2016

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Deficiency in mannose-binding lectin-associated serine protease-2 does not increase susceptibility to Trypanosoma cruzi infection.
Carolina H Ribeiro, Nicholas J Lynch, Cordula M Stover, Youssif M Ali, Carolina Valck

Am J Trop Med Hyg· February 2015

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Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4.
Elham Asgari, Conrad A Farrar, Nicholas Lynch, Youssif M Ali, Silke Roscher

FASEB J· September 2014

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Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection.
Youssif Mohammed Ali, Azam Hayat, Bayad Mawlood Saeed, Kashif S Haleem, Saleh Alshamrani, Nicholas J Lynch

Proc Natl Acad Sci U S A· April 2014

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The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.
Youssif M Ali, Nicholas J Lynch, Kashif S Haleem, Teizo Fujita, Yuichi Endo

PLoS Pathog· January 2013

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Absence of the lectin activation pathway of complement does not increase susceptibility to Pseudomonas aeruginosa infections.
Hany Ibrahim Kenawy, Youssif Mohammed Ali, Kumar Rajakumar, Nicholas J Lynch, Aras Kadioglu

Immunobiology· February 2012

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Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.
Wilhelm J Schwaeble, Nicholas J Lynch, James E Clark, Michael Marber, Nilesh J Samani

Proc Natl Acad Sci U S A· May 2011

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Use of recombinant calreticulin and cercarial transformation fluid (CTF) in the serodiagnosis of Schistosoma mansoni.
Bahaa El Deen Wade El Aswad, Michael J Doenhoff, Abeer Shawky El Hadidi, Wilhelm J Schwaeble, Nicholas J Lynch

Immunobiology· March 2011

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Small mannose-binding lectin-associated protein plays a regulatory role in the lectin complement pathway.
Daisuke Iwaki, Kazuko Kanno, Minoru Takahashi, Yuichi Endo, Nicholas J Lynch

J Immunol· December 2006

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Decoupling of carbohydrate binding and MASP-2 autoactivation in variant mannose-binding lectins associated with immunodeficiency.
Russell Wallis, Nicholas J Lynch, Silke Roscher, Kenneth B Reid, Wilhelm J Schwaeble

J Immunol· November 2005

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