Publications by authors named "Nicholas P Gauthier"

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Accessible, uniform protein property prediction with a scikit-learn based toolset AIDE.
Evan Komp, Kristoffer E Johansson, Nicholas P Gauthier, Japheth E Gado, Kresten Lindorff-Larsen

Bioinformatics· October 2025

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Machine Learning-Guided Identification of PET Hydrolases from Natural Diversity.
Brenna Norton-Baker, Evan Komp, Japheth E Gado, Mackenzie C R Denton, Irimpan I Mathews, Nicholas P Gauthier

ACS Catal· September 2025

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Development and flight-testing of modular autonomous cultivation systems for biological plastics upcycling aboard the ISS.
Xin Liu, Pat Pataranutaporn, Benjamin Fram, Allison Z Werner, Sunanda Sharma, Nicholas P Gauthier

NPJ Microgravity· June 2025

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Simultaneous enhancement of multiple functional properties using evolution-informed protein design.
Benjamin Fram, Yang Su, Ian Truebridge, Adam J Riesselman, John B Ingraham, Nicholas P Gauthier

Nat Commun· June 2024

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Enabling high-throughput enzyme discovery and engineering with a low-cost, robot-assisted pipeline.
Brenna Norton-Baker, Mackenzie C R Denton, Natasha P Murphy, Benjamin Fram, Samuel Lim, Nicholas P Gauthier

Sci Rep· June 2024

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Simultaneous enhancement of multiple functional properties using evolution-informed protein design.
Benjamin Fram, Ian Truebridge, Yang Su, Adam J Riesselman, John B Ingraham, Nicholas P Gauthier

bioRxiv· May 2023

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AlignmentViewer: Sequence Analysis of Large Protein Families.
Roc Reguant, Yevgeniy Antipin, Rob Sheridan, Christian Dallago, Drew Diamantoukos, Nicholas Paul Gauthier

F1000Res· February 2021

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Perturbation biology links temporal protein changes to drug responses in a melanoma cell line.
Elin Nyman, Richard R Stein, Xiaohong Jing, Weiqing Wang, Benjamin Marks, Nicholas P Gauthier

PLoS Comput Biol· July 2020

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Protein Structure from Experimental Evolution.
Michael A Stiffler, Frank J Poelwijk, Kelly P Brock, Richard R Stein, Adam Riesselman, Nicholas P Gauthier

Cell Syst· January 2020

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Inferring protein 3D structure from deep mutation scans.
Nathan J Rollins, Kelly P Brock, Frank J Poelwijk, Michael A Stiffler, Nicholas P Gauthier

Nat Genet· July 2019

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Systems pharmacology using mass spectrometry identifies critical response nodes in prostate cancer.
H Alexander Ebhardt, Alex Root, Yansheng Liu, Nicholas Paul Gauthier, Chris Sander

NPJ Syst Biol Appl· July 2018

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MutationAligner: a resource of recurrent mutation hotspots in protein domains in cancer.
Nicholas Paul Gauthier, Ed Reznik, Jianjiong Gao, Selcuk Onur Sumer, Nikolaus Schultz

Nucleic Acids Res· January 2016

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Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
Martin L Miller, Ed Reznik, Nicholas P Gauthier, Bülent Arman Aksoy, Anil Korkut

Cell Syst· September 2015

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Perturbation biology: inferring signaling networks in cellular systems.
Evan J Molinelli, Anil Korkut, Weiqing Wang, Martin L Miller, Nicholas P Gauthier

PLoS Comput Biol· August 2014

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Cell-selective labeling using amino acid precursors for proteomic studies of multicellular environments.
Nicholas P Gauthier, Boumediene Soufi, William E Walkowicz, Virginia A Pedicord, Konstantinos J Mavrakis

Nat Methods· August 2013

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Cyclebase.org: version 2.0, an updated comprehensive, multi-species repository of cell cycle experiments and derived analysis results.
Nicholas Paul Gauthier, Lars Juhl Jensen, Rasmus Wernersson, Søren Brunak, Thomas S Jensen

Nucleic Acids Res· January 2010

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Cyclebase.org--a comprehensive multi-organism online database of cell-cycle experiments.
Nicholas Paul Gauthier, Malene Erup Larsen, Rasmus Wernersson, Ulrik de Lichtenberg, Lars Juhl Jensen

Nucleic Acids Res· January 2008

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Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay.
Laurent Perreard, Cheng Fan, John F Quackenbush, Michael Mullins, Nicholas P Gauthier

Breast Cancer Res· July 2006

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