Publications by authors named "Nicholas Pagano"

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An integrated chemical biology approach reveals the mechanism of action of HIV replication inhibitors.
Nicholas Pagano, Peter Teriete, Margrith E Mattmann, Li Yang, Beth A Snyder

Bioorg Med Chem· December 2017

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GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation.
Jobin K John, Kim H T Paraiso, Vito W Rebecca, Liliana P Cantini, Ethan V Abel, Nicholas Pagano

J Invest Dermatol· December 2012

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Automated Multistep Continuous Flow Synthesis of 2-(-Indol-3-yl)thiazole Derivatives.
Nicholas Pagano, Marintha L Heil, Nicholas D P Cosford

Synthesis (Stuttg)· January 2012

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An Automated Process for a Sequential Heterocycle/Multicomponent Reaction: Multistep Continuous Flow Synthesis of 5-(Thiazol-2-yl)-3,4-Dihydropyrimidin-2()-ones.
Nicholas Pagano, Ananda Herath, Nicholas D P Cosford

J Flow Chem· August 2011

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From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors.
Nicholas Pagano, Eric Y Wong, Tom Breiding, Haidong Liu, Alexander Wilbuer

J Org Chem· December 2009

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Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
Alex N Bullock, Santina Russo, Ann Amos, Nicholas Pagano, Howard Bregman

PLoS One· October 2009

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The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase.
Peng Xie, Craig Streu, Jie Qin, Howard Bregman, Nicholas Pagano

Biochemistry· June 2009

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Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor.
Ruchi Anand, Jasna Maksimoska, Nicholas Pagano, Eric Y Wong, Phyllis A Gimotty

J Med Chem· March 2009

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Metal-mediated base pairing within the simplified nucleic acid GNA.
Mark K Schlegel, Lilu Zhang, Nicholas Pagano, Eric Meggers

Org Biomol Chem· February 2009

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Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3.
G Ekin Atilla-Gokcumen, Nicholas Pagano, Craig Streu, Jasna Maksimoska, Panagis Filippakopoulos

Chembiochem· December 2008

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Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand.
Nicholas Pagano, Jasna Maksimoska, Howard Bregman, Douglas S Williams, Richard D Webster

Org Biomol Chem· April 2007

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Organometallic compounds with biological activity: a very selective and highly potent cellular inhibitor for glycogen synthase kinase 3.
G Ekin Atilla-Gokcumen, Douglas S Williams, Howard Bregman, Nicholas Pagano, Eric Meggers

Chembiochem· September 2006

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Use of design of experiments to optimize high-throughput semipreparative LC and LC/MS methods.
Derek C Cole, Nicholas Pagano, Michael F Kelly, John Ellingboe

J Comb Chem· June 2004

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