Publications by authors named "Nicholas Popescu"

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Cooperative antiproliferative effect of coordinated ectopic expression of DLC1 tumor suppressor protein and silencing of MYC oncogene expression in liver cancer cells: Therapeutic implications.
Xuyu Yang, Xiaoling Zhou, Paul Tone, Marian E Durkin, Nicholas C Popescu

Oncol Lett· August 2016

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Deleted in liver cancer-1 (DLC1): an emerging metastasis suppressor gene.
Nicholas C Popescu, Steve Goodison

Mol Diagn Ther· June 2014

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DLC1 suppresses NF-κB activity in prostate cancer cells due to its stabilizing effect on adherens junctions.
Veenu Tripathi, Nicholas C Popescu, Drazen B Zimonjic

Springerplus· March 2014

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Isolation of Mouse Embryo Fibroblasts.
Marian E Durkin, Xiaolan Qian, Nicholas C Popescu, Douglas R Lowy

Bio Protoc· September 2013

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In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells.
Drazen B Zimonjic, Lai N Chan, Veenu Tripathi, Jie Lu, Ohyun Kwon, Nicholas C Popescu

BMC Cancer· April 2013

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Inactivation of the Dlc1 gene cooperates with downregulation of p15INK4b and p16Ink4a, leading to neoplastic transformation and poor prognosis in human cancer.
Xiaolan Qian, Marian E Durkin, Dunrui Wang, Brajendra K Tripathi, Lyra Olson, Nicholas C Popescu

Cancer Res· November 2012

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Role of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: potential prospects for combined targeted therapeutics (review).
Drazen B Zimonjic, Nicholas C Popescu

Int J Oncol· August 2012

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DLC1 interaction with α-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activity.
Veenu Tripathi, Nicholas C Popescu, Drazen B Zimonjic

Mol Cell Biol· June 2012

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Preclinical evaluation of combined antineoplastic effect of DLC1 tumor suppressor protein and suberoylanilide hydroxamic acid on prostate cancer cells.
Xiaoling Zhou, Xu-Yu Yang, Nicholas C Popescu

Biochem Biophys Res Commun· April 2012

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Restoration of senescence in breast and ovarian cancer cells following the transfer of the YAC carrying SEN6A gene located at 6q16.3.
Neena S Rane, Arbansjit K Sandhu, Vikramjit S Zhawar, Gurpreet Kaur, Nicholas C Popescu

Cancer Genomics Proteomics· February 2012

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DLC1 interaction with S100A10 mediates inhibition of in vitro cell invasion and tumorigenicity of lung cancer cells through a RhoGAP-independent mechanism.
Xuyu Yang, Nicholas C Popescu, Drazen B Zimonjic

Cancer Res· April 2011

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Synergistic antineoplastic effect of DLC1 tumor suppressor protein and histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), on prostate and liver cancer cells: perspectives for therapeutics.
Xiaoling Zhou, Xu-Yu Yang, Nicholas C Popescu

Int J Oncol· April 2010

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Role of SV40 integration site at chromosomal interval 1q21.1 in immortalized CRL2504 cells.
Jinglan Liu, Gurpreet Kaur, Vikramjit K Zhawar, Drazen B Zimonjic, Nicholas C Popescu

Cancer Res· October 2009

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Acquired genetic and functional alterations associated with transforming growth factor beta type I resistance in Hep3B human hepatocellular carcinoma cell line.
Drazen B Zimonjic, Xiaoling Zhou, Ju-Seog Lee, Veronika Ullmannova-Benson, Veenu Tripathi, Nicholas C Popescu

J Cell Mol Med· September 2009

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Recurrent and nonrandom DNA copy number and chromosome alterations in Myc transgenic mouse model for hepatocellular carcinogenesis: implications for human disease.
Drazen B Zimonjic, Veronika Ullmannova-Benson, Valentina M Factor, Snorri S Thorgeirsson, Nicholas C Popescu

Cancer Genet Cytogenet· May 2009

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DLC1 suppresses distant dissemination of human hepatocellular carcinoma cells in nude mice through reduction of RhoA GTPase activity, actin cytoskeletal disruption and down-regulation of genes involved in metastasis.
Xiaoling Zhou, Drazen B Zimonjic, Sang-Won Park, Xu-Yu Yang, Marian E Durkin, Nicholas C Popescu

Int J Oncol· June 2008

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DLC-1:a Rho GTPase-activating protein and tumour suppressor.
Marian E Durkin, Bao-Zhu Yuan, Xiaoling Zhou, Drazen B Zimonjic, Douglas R Lowy, Nicholas C Popescu

J Cell Mol Med· January 2008

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Delayed kinetics of DNA double-strand break processing in normal and pathological aging.
Olga A Sedelnikova, Izumi Horikawa, Christophe Redon, Asako Nakamura, Drazen B Zimonjic, Nicholas C Popescu

Aging Cell· January 2008

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Morphological changes and nuclear translocation of DLC1 tumor suppressor protein precede apoptosis in human non-small cell lung carcinoma cells.
Bao-Zhu Yuan, Amy M Jefferson, Lyndell Millecchia, Nicholas C Popescu, Steven H Reynolds

Exp Cell Res· November 2007

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Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity.
Mai-Jing Liao, Cheng Cheng Zhang, Beiyan Zhou, Drazen B Zimonjic, Sendurai A Mani, Nicholas C Popescu

Cancer Res· September 2007

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Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses.
Ze-Hong Miao, Audrey Player, Uma Shankavaram, Yong-Hong Wang, Drazen B Zimonjic, Nicholas C Popescu

Cancer Res· September 2007

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The interferon-alpha responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma.
Xiaoling Zhou, Nicholas C Popescu, George Klein, Stephan Imreh

Cancer Genet Cytogenet· August 2007

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Inhibition of cell proliferation, induction of apoptosis, reactivation of DLC1, and modulation of other gene expression by dietary flavone in breast cancer cell lines.
Veronika Ullmannova, Nicholas C Popescu

Cancer Detect Prev· July 2007

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Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities.
Xiaolan Qian, Guorong Li, Holly K Asmussen, Laura Asnaghi, William C Vass, Nicholas C Popescu

Proc Natl Acad Sci U S A· May 2007

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Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors.
Veronika Ullmannova, Nicholas C Popescu

Int J Oncol· November 2006

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