Publications by authors named "Nicholas Porter"

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A compact tabletop extreme-ultraviolet source for polarization-sensitive ptychographic imaging.
Taylor J Buckway, Aaron Redd, Hyrum Taylor, Jacob Feltman, Kaylee Nyborg, J Nicholas Porter

Rev Sci Instrum· August 2025

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The β-subunit of tryptophan synthase is a latent tyrosine synthase.
Patrick J Almhjell, Kadina E Johnston, Nicholas J Porter, Jennifer L Kennemur, Vignesh C Bhethanabotla

Nat Chem Biol· August 2024

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A combinatorially complete epistatic fitness landscape in an enzyme active site.
Kadina E Johnston, Patrick J Almhjell, Ella J Watkins-Dulaney, Grace Liu, Nicholas J Porter

Proc Natl Acad Sci U S A· August 2024

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Iron Heme Enzyme-Catalyzed Cyclopropanations with Diazirines as Carbene Precursors: Computational Explorations of Diazirine Activation and Cyclopropanation Mechanism.
Torben Rogge, Qingyang Zhou, Nicholas J Porter, Frances H Arnold, K N Houk

J Am Chem Soc· February 2024

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Mapping nanocrystal orientations via scanning Laue diffraction microscopy for multi-peak Bragg coherent diffraction imaging.
Yueheng Zhang, J Nicholas Porter, Matthew J Wilkin, Ross Harder, Wonsuk Cha

J Synchrotron Radiat· July 2023

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MicroED Structure of a Protoglobin Reactive Carbene Intermediate.
Emma Danelius, Nicholas J Porter, Johan Unge, Frances H Arnold, Tamir Gonen

J Am Chem Soc· April 2023

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Chemodivergent C(sp)-H and C(sp)-H Cyanomethylation Using Engineered Carbene Transferases.
Juner Zhang, Ailiena O Maggiolo, Edwin Alfonzo, Runze Mao, Nicholas J Porter

Nat Catal· February 2023

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Biocatalytic Carbene Transfer Using Diazirines.
Nicholas J Porter, Emma Danelius, Tamir Gonen, Frances H Arnold

J Am Chem Soc· May 2022

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Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders.
Jeremy D Osko, Nicholas J Porter, Christophe Decroos, Matthew S Lee, Paris R Watson

J Struct Biol· March 2021

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Talking About Public Health With African American Men: Perceptions of Environmental Health and Infertility.
Nathan McCray, Lance Thompson, Francesca Branch, Nicholas Porter, James Peterson

Am J Mens Health· February 2021

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Laser wavelength metrology with low-finesse etalons and Bayer filters.
J Nicholas Porter, Jarom S Jackson, Dallin S Durfee, Richard L Sandberg

Opt Express· December 2020

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Hemispheric Cerebral Oximetry Monitoring During Pediatric Seizure Activity in a Pediatric Emergency Department.
Thomas J Abramo, Shane McKinney, James Moore, Richard Jacobs, Gregory Albert, Nicholas Hobart Porter

Pediatr Emerg Care· September 2020

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Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.
Michael Morgen, Raphael R Steimbach, Magalie Géraldy, Lars Hellweg, Peter Sehr, Nicholas J Porter

ChemMedChem· July 2020

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Preparation of a new construct of human histone deacetylase 8 for the crystallization of enzyme-inhibitor complexes.
Nicholas J Porter, David W Christianson

Methods Enzymol· June 2020

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Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6.
Jeremy D Osko, Nicholas J Porter, Poli Adi Narayana Reddy, You-Cai Xiao, Johanna Rokka

J Med Chem· January 2020

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Structure, mechanism, and inhibition of the zinc-dependent histone deacetylases.
Nicholas J Porter, David W Christianson

Curr Opin Struct Biol· December 2019

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Aza-proline effectively mimics l-proline stereochemistry in triple helical collagen.
Alexander J Kasznel, Trevor Harris, Nicholas J Porter, Yitao Zhang, David M Chenoweth

Chem Sci· August 2019

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Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
Katharina Vögerl, Nghia Ong, Johanna Senger, Daniel Herp, Karin Schmidtkunz, Nicholas J Porter

J Med Chem· February 2019

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Molecular Basis for the Selective Inhibition of Histone Deacetylase 6 by a Mercaptoacetamide Inhibitor.
Nicholas J Porter, Sida Shen, Cyril Barinka, Alan P Kozikowski, David W Christianson

ACS Med Chem Lett· December 2018

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Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity.
Nicholas J Porter, Jeremy D Osko, Daniela Diedrich, Thomas Kurz, Jacob M Hooker

J Med Chem· September 2018

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Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6.
Nicholas J Porter, Florence F Wagner, David W Christianson

Biochemistry· July 2018

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Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors.
Nicholas J Porter, Adaickapillai Mahendran, Ronald Breslow, David W Christianson

Proc Natl Acad Sci U S A· December 2017

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Semi-automated scoring of triple-probe FISH in human sperm using confocal microscopy.
Francesca Branch, GiaLinh Nguyen, Nicholas Porter, Heather A Young, Sheena E Martenies

Cytometry A· September 2017

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Binding of the Microbial Cyclic Tetrapeptide Trapoxin A to the Class I Histone Deacetylase HDAC8.
Nicholas J Porter, David W Christianson

ACS Chem Biol· September 2017

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Persistent negative effects of alcohol drinking on aspects of novelty-directed behavior in male rhesus macaques.
Cassie M Chandler, Meagan E Follett, Nicholas J Porter, Kevin Y Liang, Eric J Vallender

Alcohol· September 2017

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