Publications by authors named "Nicholas Riola"

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Oral dosing of the nucleoside analog obeldesivir is efficacious against RSV infection in African green monkeys.
Jared Pitts, J Lizbeth Reyes Zamora, Savrina Manhas, Thomas Aeschbacher, Josolyn Chan, Nicholas C Riola

Nat Commun· July 2025

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Discovery of GS-7682, a Novel 4'-Cyano-Modified -Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.
Dustin S Siegel, Hon C Hui, Jared Pitts, Meghan S Vermillion, Kazuya Ishida, Nicholas C Riola

J Med Chem· August 2024

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Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys.
Richard L Mackman, Rao V Kalla, Darius Babusis, Jared Pitts, Kimberly T Barrett, Nicholas C Riola

J Med Chem· September 2023

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Intravenous delivery of GS-441524 is efficacious in the African green monkey model of SARS-CoV-2 infection.
Jared Pitts, Darius Babusis, Meghan S Vermillion, Raju Subramanian, Kim Barrett, Nicholas Riola

Antiviral Res· July 2022

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Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance.
Liva Checkmahomed, Julie Carbonneau, Venice Du Pont, Nicholas C Riola, Jason K Perry

Antimicrob Agents Chemother· July 2022

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Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants.
Jared Pitts, Jiani Li, Jason K Perry, Venice Du Pont, Nicholas Riola

Antimicrob Agents Chemother· June 2022

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