Publications by authors named "Nicholas Rotile"

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Multimodal Imaging Demonstrates Antifibrotic Effects of Targeting α v β 6 /α v β 1 Integrins in Biliary Fibrosis.
Yingying Ning, Iris Y Zhou, Johanna R Schaub, Nicholas J Rotile, Avery Boice

Invest Radiol· January 2026

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Molecular MRI of Dysregulated Zinc Secretion Detects Pancreatic Ductal Adenocarcinoma and Response to KRASG12D Inhibitor Treatment.
Veronica Clavijo Jordan, Mozhdeh Sojoodi, Farzad Moloudi, Patricia Gonzalez Pagan, Manyu Jin, Nicholas Rotile

Cancer Res· November 2025

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F-FPP-RGD PET Imaging for Interrogating Target Engagement and Antifibrotic Activity of an Integrin Antagonist in a Mouse Model of Metabolic Dysfunction-Associated Steatohepatitis.
Iris Y Zhou, Caiyuan Zhang, Mozhdeh Sojoodi, Nicholas J Rotile, Yu Lan

J Nucl Med· November 2025

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Author Correction: Manganese-based type I collagen-targeting MRI probe for in vivo imaging of liver fibrosis.
Chunxiang Zhang, Hua Ma, Daniel DeRoche, Eric M Gale, Pamela Pantazopoulos, Nicholas J Rotile

Npj Imaging· October 2025

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Manganese-based type I collagen-targeting MRI probe for in vivo imaging of liver fibrosis.
Chunxiang Zhang, Hua Ma, Daniel DeRoche, Eric M Gale, Pamela Pantazopoulos, Nicholas J Rotile

Npj Imaging· April 2025

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Development of a fibrin-targeted theranostic for gastric cancer.
Shadi A Esfahani, Li Ma, Shriya Krishna, Hua Ma, Shvan J Raheem, Nicholas J Rotile

Sci Transl Med· December 2024

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Manganese-based type I collagen-targeting MRI probe for in vivo imaging of liver fibrosis.
Chunxiang Zhang, Hua Ma, Daniel DeRoche, Eric M Gale, Pamela Pantazopoulos, Nicholas J Rotile

Res Sq· November 2024

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Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies.
Shadi A Esfahani, Hua Ma, Shriya Krishna, Sergey Shuvaev, Mark Sabbagh, Nicholas Rotile

Theranostics· September 2024

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Allysine-Targeted Molecular MRI Enables Early Prediction of Chemotherapy Response in Pancreatic Cancer.
Hua Ma, Shadi A Esfahani, Shriya Krishna, Bahar Ataeinia, Iris Y Zhou, Nicholas J Rotile

Cancer Res· August 2024

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Simultaneous Positron Emission Tomography and Molecular Magnetic Resonance Imaging of Cardiopulmonary Fibrosis in a Mouse Model of Left Ventricular Dysfunction.
Brianna F Moon, Iris Y Zhou, Yingying Ning, Yin-Ching I Chen, Mariane Le Fur, Nicholas Rotile

J Am Heart Assoc· July 2024

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Noninvasive Quantification of Radiation-Induced Lung Injury Using a Targeted Molecular Imaging Probe.
Eric Abston, Iris Y Zhou, Jonathan A Saenger, Sergey Shuvaev, Eman Akam, Nicholas J Rotile

Int J Radiat Oncol Biol Phys· April 2024

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Detection of Pulmonary Fibrosis with a Collagen-Mimetic Peptide.
Isabella M Borgula, Sergey Shuvaev, Eric Abston, Nicholas J Rotile, Jonah Weigand-Whittier

ACS Sens· November 2023

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Optimization of an Allysine-Targeted PET Probe for Quantifying Fibrogenesis in a Mouse Model of Pulmonary Fibrosis.
Sergey Shuvaev, Rachel S Knipe, Matt Drummond, Nicholas J Rotile, Ilknur Ay

Mol Imaging Biol· October 2023

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Gadolinium-based Contrast Agent Biodistribution and Speciation in Rats.
Mariane Le Fur, Brianna F Moon, Iris Y Zhou, Samantha Zygmont, Avery Boice, Nicholas J Rotile

Radiology· October 2023

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Tailored Chemical Reactivity Probes for Systemic Imaging of Aldehydes in Fibroproliferative Diseases.
Hua Ma, Iris Y Zhou, Y Iris Chen, Nicholas J Rotile, Ilknur Ay

J Am Chem Soc· September 2023

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Noninvasive Quantification of Radiation-Induced Lung Injury using a Targeted Molecular Imaging Probe.
Eric Abston, Iris Y Zhou, Jonathan A Saenger, Sergey Shuvaev, Eman Akam, Nicholas J Rotile

medRxiv· September 2023

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Molecular MR Imaging of Renal Fibrogenesis in Mice.
Yin-Ching Chen, Philip A Waghorn, Ivy A Rosales, Gunisha Arora, Derek J Erstad, Nicholas J Rotile

J Am Soc Nephrol· July 2023

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Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via -weighted MRI.
Juanye Zhang, Yingying Ning, Hua Zhu, Nicholas J Rotile, He Wei

Proc Natl Acad Sci U S A· May 2023

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HER3 PET Imaging Predicts Response to Pan Receptor Tyrosine Kinase Inhibition Therapy in Gastric Cancer.
Shadi A Esfahani, Carolina de Aguiar Ferreira, Nicholas J Rotile, Bahar Ataeinia, Shriya Krishna

Mol Imaging Biol· April 2023

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Tailored chemical reactivity probes for systemic imaging of aldehydes in fibroproliferative diseases.
Hua Ma, Iris Y Zhou, Y Iris Chen, Nicholas J Rotile, Ilknur Ay

bioRxiv· April 2023

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Hyperpolarized [1-C]Pyruvate Magnetic Resonance Spectroscopic Imaging for Evaluation of Early Response to Tyrosine Kinase Inhibition Therapy in Gastric Cancer.
Shadi A Esfahani, Cody Callahan, Nicholas J Rotile, Pedram Heidari, Umar Mahmood

Mol Imaging Biol· October 2022

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Dual Hydrazine-Equipped Turn-On Manganese-Based Probes for Magnetic Resonance Imaging of Liver Fibrogenesis.
Yingying Ning, Iris Yuwen Zhou, Nicholas J Rotile, Pamela Pantazopoulos, Huan Wang

J Am Chem Soc· September 2022

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Molecular MRI quantification of extracellular aldehyde pairs for early detection of liver fibrogenesis and response to treatment.
Yingying Ning, Iris Y Zhou, Jesse D Roberts, Nicholas J Rotile, Eman Akam

Sci Transl Med· September 2022

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Imaging High-Risk Atherothrombosis Using a Novel Fibrin-Binding Positron Emission Tomography Probe.
David Izquierdo-Garcia, Himashinie Diyabalanage, Ian A Ramsay, Nicholas J Rotile, Adam Mauskapf

Stroke· February 2022

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Radiolabeling and PET-MRI microdosing of the experimental cancer therapeutic, MN-anti-miR10b, demonstrates delivery to metastatic lesions in a murine model of metastatic breast cancer.
Mariane Le Fur, Alana Ross, Pamela Pantazopoulos, Nicholas Rotile, Iris Zhou

Cancer Nanotechnol· July 2021

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