Publications by authors named "Nicholas Trahearn"

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Epigenetically driven and early immune evasion in colorectal cancer evolution.
Eszter Lakatos, Vinaya Gunasri, Luis Zapata, Jacob Househam, Timon Heide, Nicholas Trahearn

Nat Genet· December 2025

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Computational pathology applied to clinical colorectal cancer cohorts identifies immune and endothelial cell spatial patterns predictive of outcome.
Nicholas Trahearn, Chirine Sakr, Abhirup Banerjee, Seung Hyun Lee, Ann-Marie Baker

J Pathol· February 2025

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Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer.
Javier Fernandez-Mateos, George D Cresswell, Nicholas Trahearn, Katharine Webb, Chirine Sakr

Nat Cancer· September 2024

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Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer.
Eszter Lakatos, Vinaya Gunasri, Luis Zapata, Jacob Househam, Timon Heide, Nicholas Trahearn

bioRxiv· February 2024

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Exploiting evolutionary steering to induce collateral drug sensitivity in cancer.
Ahmet Acar, Daniel Nichol, Javier Fernandez-Mateos, George D Cresswell, Iros Barozzi, Nicholas Trahearn

Nat Commun· April 2020

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Analysis of tumour ecological balance reveals resource-dependent adaptive strategies of ovarian cancer.
Sidra Nawaz, Nicholas A Trahearn, Andreas Heindl, Susana Banerjee, Carlo C Maley

EBioMedicine· October 2019

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The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer.
Peter Barry, Alexandra Vatsiou, Inmaculada Spiteri, Daniel Nichol, George D Cresswell, Nicholas Trahearn

Clin Cancer Res· October 2018

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Stain Deconvolution Using Statistical Analysis of Multi-Resolution Stain Colour Representation.
Najah Alsubaie, Nicholas Trahearn, Shan E Ahmed Raza, David Snead, Nasir M Rajpoot

PLoS One· August 2017

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Hyper-Stain Inspector: A Framework for Robust Registration and Localised Co-Expression Analysis of Multiple Whole-Slide Images of Serial Histology Sections.
Nicholas Trahearn, David Epstein, Ian Cree, David Snead, Nasir Rajpoot

Sci Rep· July 2017

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Simultaneous automatic scoring and co-registration of hormone receptors in tumor areas in whole slide images of breast cancer tissue slides.
Nicholas Trahearn, Yee Wah Tsang, Ian A Cree, David Snead, David Epstein

Cytometry A· June 2017

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