Publications by authors named "Nicholas Yoder"

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FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models.
Timothy Weeden, Tyler Picariello, Brendan Quinn, Sean Spring, Pei-Yi Shen, Nicholas Yoder

Commun Med (Lond)· January 2025

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Preclinical Evaluation of IMGC936, a Next-Generation Maytansinoid-based Antibody-drug Conjugate Targeting ADAM9-expressing Tumors.
Juniper A Scribner, Stuart W Hicks, Kerstin W Sinkevicius, Nicholas C Yoder, Gundo Diedrich

Mol Cancer Ther· July 2022

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Systemic social and emotional learning: Promoting educational success for all preschool to high school students.
Joseph L Mahoney, Roger P Weissberg, Mark T Greenberg, Linda Dusenbury, Robert J Jagers, Nicholas Yoder

Am Psychol· October 2021

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Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine Conjugation.
Chen Bai, Emily E Reid, Alan Wilhelm, Manami Shizuka, Erin K Maloney, Nicholas C Yoder

Bioconjug Chem· January 2020

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A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation.
Nicholas C Yoder, Chen Bai, Daniel Tavares, Wayne C Widdison, Kathleen R Whiteman

Mol Pharm· September 2019

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Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs).
Emily E Reid, Katie E Archer, Manami Shizuka, Molly A McShea, Erin K Maloney, Nicholas C Yoder

Bioorg Med Chem Lett· September 2019

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Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody-Drug Conjugates (ADCs).
Emily E Reid, Katie E Archer, Manami Shizuka, Alan Wilhelm, Nicholas C Yoder

ACS Med Chem Lett· August 2019

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A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells.
Yelena Kovtun, Gregory E Jones, Sharlene Adams, Lauren Harvey, Charlene A Audette, Nicholas C Yoder

Blood Adv· April 2018

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A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody-Drug Conjugates (ADCs).
Michael L Miller, Manami Shizuka, Alan Wilhelm, Paulin Salomon, Emily E Reid, Nicholas C Yoder

Mol Cancer Ther· March 2018

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Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.
Carl U Bialucha, Scott D Collins, Xiao Li, Parmita Saxena, Xiamei Zhang, Nicholas C Yoder

Cancer Discov· September 2017

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Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates.
Xiuxia Sun, Jose F Ponte, Nicholas C Yoder, Rassol Laleau, Jennifer Coccia

Bioconjug Chem· May 2017

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Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates.
Kalli C Catcott, Molly A McShea, Carl Uli Bialucha, Kathy L Miller, Stuart W Hicks, Nicholas C Yoder

MAbs· December 2016

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Understanding How the Stability of the Thiol-Maleimide Linkage Impacts the Pharmacokinetics of Lysine-Linked Antibody-Maytansinoid Conjugates.
Jose F Ponte, Xiuxia Sun, Nicholas C Yoder, Nathan Fishkin, Rassol Laleau

Bioconjug Chem· July 2016

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The chlamydial OTU domain-containing protein ChlaOTU is an early type III secretion effector targeting ubiquitin and NDP52.
Ana Rita Furtado, Miriam Essid, Stéphanie Perrinet, María Eugenia Balañá, Nicholas Yoder

Cell Microbiol· December 2013

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Catch-and-release probes applied to semi-intact cells reveal ubiquitin-specific protease expression in Chlamydia trachomatis infection.
Jasper H L Claessen, Martin D Witte, Nicholas C Yoder, Angela Y Zhu, Eric Spooner

Chembiochem· February 2013

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Preparation of unnatural N-to-N and C-to-C protein fusions.
Martin D Witte, Juan J Cragnolini, Stephanie K Dougan, Nicholas C Yoder, Maximilian W Popp

Proc Natl Acad Sci U S A· July 2012

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Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity.
Jenny M Tam, Michael K Mansour, Nida S Khan, Nicholas C Yoder, Jatin M Vyas

Integr Biol (Camb)· February 2012

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Lipopeptides derived from HIV and SIV mimicking the prehairpin intermediate of gp41 on solid supported lipid bilayers.
Steffen Schuy, Edith Schäfer, Nicholas C Yoder, Krishna Kumar, Reiner Vogel

J Struct Biol· October 2009

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Site-specific N- and C-terminal labeling of a single polypeptide using sortases of different specificity.
John M Antos, Guo-Liang Chew, Carla P Guimaraes, Nicholas C Yoder, Gijsbert M Grotenbreg

J Am Chem Soc· August 2009

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Coiled-coil lipopeptides mimicking the prehairpin intermediate of glycoprotein gp41.
Steffen Schuy, Edith Schäfer, Nicholas C Yoder, Stephan Hobe, Krishna Kumar

Angew Chem Int Ed Engl· January 2009

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Structure and thermotropic phase behavior of fluorinated phospholipid bilayers: a combined attenuated total reflection FTIR spectroscopy and imaging ellipsometry study.
Steffen Schuy, Simon Faiss, Nicholas C Yoder, Venkateshwarlu Kalsani, Krishna Kumar

J Phys Chem B· July 2008

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Identity-based motivation and health.
Daphna Oyserman, Stephanie A Fryberg, Nicholas Yoder

J Pers Soc Psychol· December 2007

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Nanoscale patterning in mixed fluorocarbon-hydrocarbon phospholipid bilayers.
Nicholas C Yoder, Venkateshwarlu Kalsani, Steffen Schuy, Reiner Vogel, Andreas Janshoff

J Am Chem Soc· July 2007

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The role of conserved histidines in the structure and stability of human papillomavirus type 16 E2 DNA-binding domain.
Kakoli Bose, Nicholas C Yoder, Krishna Kumar, James D Baleja

Biochemistry· February 2007

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Bioorthogonal noncovalent chemistry: Fluorous phases in chemical biology.
Nicholas C Yoder, Deniz Yüksel, Laila Dafik, Krishna Kumar

Curr Opin Chem Biol· December 2006

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