Publications by authors named "Nichole Pedowitz"

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A Two-Step Synthesis of Covalent Genetically-Encoded Libraries of Peptide-Derived Macrocycles (cGELs) enables use of electrophiles with diverse reactivity.
James H Walker, Arunika I Ekanayake, Nichole Pedowitz, Ryan Qiu, Peter Girnt

bioRxiv· August 2025

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Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation.
Tulsi Upadhyay, Emily C Woods, Stephen Dela Ahator, Kjersti Julin, Franco F Faucher, Nichole J Pedowitz

Nat Commun· May 2025

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An mRNA Display Approach for Covalent Targeting of a Virulence Factor.
Sijie Wang, Emily C Woods, Jeyun Jo, Jiyun Zhu, Althea Hansel-Harris, Nichole J Pedowitz

J Am Chem Soc· March 2025

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Covalent-fragment screening identifies selective inhibitors of multiple Staphylococcus aureus serine hydrolases important for growth and biofilm formation.
Matthew Bogyo, Tulsi Upadhyay, Emily Woods, Stephen Ahator, Kjersti Julin, Nichole Pedowitz

Res Sq· December 2024

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An mRNA Display Approach for Covalent Targeting of a Virulence Factor.
Sijie Wang, Emily C Woods, Jeyun Jo, Jiyun Zhu, Althea Hansel-Harris, Nichole J Pedowitz

bioRxiv· November 2024

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Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Infections.
Jeyun Jo, Tulsi Upadhyay, Emily C Woods, Ki Wan Park, Nichole J Pedowitz

J Am Chem Soc· March 2024

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Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Infections.
Jeyun Jo, Tulsi Upadhyay, Emily C Woods, Ki Wan Park, Nichole J Pedowitz

bioRxiv· December 2023

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A photoaffinity glycan-labeling approach to investigate immunoglobulin glycan-binding partners.
Miles D Holborough-Kerkvliet, Greta Mucignato, Sam J Moons, Venetia Psomiadou, Rohit S R Konada, Nichole J Pedowitz

Glycobiology· October 2023

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Exo-Enzymatic Addition of Diazirine-Modified Sialic Acid to Cell Surfaces Enables Photocrosslinking of Glycoproteins.
Nageswari Yarravarapu, Rohit Sai Reddy Konada, Narek Darabedian, Nichole J Pedowitz, Soumya N Krishnamurthy

Bioconjug Chem· May 2022

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A 2D and 3D cell culture protocol to study O-GlcNAc in sphingosine-1-phosphate mediated fibroblast contraction.
Murielle M Morales, Nichole J Pedowitz, Matthew R Pratt

STAR Protoc· March 2022

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Anomeric Fatty Acid Functionalization Prevents Nonenzymatic -Glycosylation by Monosaccharide Metabolic Chemical Reporters.
Nichole J Pedowitz, Emma G Jackson, Justin M Overhulse, Charles E McKenna, Jennifer J Kohler

ACS Chem Biol· October 2021

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O-GlcNAc modification of MYPT1 modulates lysophosphatidic acid-induced cell contraction in fibroblasts.
Murielle M Morales, Nichole J Pedowitz, Matthew R Pratt

J Biol Chem· August 2021

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O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity.
Aaron T Balana, Paul M Levine, Timothy W Craven, Somnath Mukherjee, Nichole J Pedowitz

Nat Chem· May 2021

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Design and Synthesis of Metabolic Chemical Reporters for the Visualization and Identification of Glycoproteins.
Nichole J Pedowitz, Matthew R Pratt

RSC Chem Biol· April 2021

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MYPT1 O-GlcNAc modification regulates sphingosine-1-phosphate mediated contraction.
Nichole J Pedowitz, Anna R Batt, Narek Darabedian, Matthew R Pratt

Nat Chem Biol· February 2021

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Inhibiting the Hexosamine Biosynthetic Pathway Lowers O-GlcNAcylation Levels and Sensitizes Cancer to Environmental Stress.
Lisa A Walter, Yu Hsuan Lin, Christopher J Halbrook, Kelly N Chuh, Lina He, Nichole J Pedowitz

Biochemistry· September 2020

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Metabolic Labeling for the Visualization and Identification of Potentially O-GlcNAc-Modified Proteins.
Nichole J Pedowitz, Balyn W Zaro, Matthew R Pratt

Curr Protoc Chem Biol· June 2020

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Endotoxin reduction in protein solutions using octyl β-D-1-thioglucopyranoside wash on chromatography media.
Dhanesh Gadre, Marcia Carlson, Ashley Mullan, Ivy Kabundi, Nichole Pedowitz

J Chromatogr A· November 2018

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Uncaging Alcohols Using UV or Visible Light Photoinduced Electron Transfer to 9-Phenyl-9-tritylone Ethers.
Derek M Denning, Nichole J Pedowitz, Matthew D Thum, Daniel E Falvey

Org Lett· December 2015

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