Publications by authors named "Nick Plant"

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Pre-emptive rituximab and plasma exchange does not prevent disease recurrence following living donor renal transplantation in high-risk idiopathic SRNS.
Mohan Shenoy, Rachel Lennon, Nick Plant, Dean Wallace, Amrit Kaur

Pediatr Nephrol· June 2020

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Linking physiologically-based pharmacokinetic and genome-scale metabolic networks to understand estradiol biology.
Joanna H Sier, Alfred E Thumser, Nick J Plant

BMC Syst Biol· December 2017

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Integration of Genome Scale Metabolic Networks and Gene Regulation of Metabolic Enzymes With Physiologically Based Pharmacokinetics.
Elaina M Maldonado, Vytautas Leoncikas, Ciarán P Fisher, J Bernadette Moore, Nick J Plant

CPT Pharmacometrics Syst Pharmacol· November 2017

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Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices.
Daphnee S Pushparajah, Kathryn E Plant, Nick J Plant, Costas Ioannides

Environ Toxicol· March 2017

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Can a systems approach produce a better understanding of mood disorders?
Nick Plant

Biochim Biophys Acta Gen Subj· January 2017

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Activation of the Farnesoid X-receptor in breast cancer cell lines results in cytotoxicity but not increased migration potential.
Noura Alasmael, Rati Mohan, Lisiane B Meira, Karen E Swales, Nick J Plant

Cancer Lett· January 2016

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Generation of 2,000 breast cancer metabolic landscapes reveals a poor prognosis group with active serotonin production.
Vytautas Leoncikas, Huihai Wu, Lara T Ward, Andrzej M Kierzek, Nick J Plant

Sci Rep· January 2016

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Inhibition of prenyltransferase activity by statins in both liver and muscle cell lines is not causative of cytotoxicity.
Rowena H Gee, Jenny N Spinks, Jason M Malia, Jonathan D Johnston, Nick J Plant, Kathryn E Plant

Toxicology· March 2015

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Systems biology approaches for studying the pathogenesis of non-alcoholic fatty liver disease.
Ciarán P Fisher, Andrzej M Kierzek, Nick J Plant, J Bernadette Moore

World J Gastroenterol· November 2014

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Primary liver cells cultured on carbon nanotube substrates for liver tissue engineering and drug discovery applications.
Che Azurahanim Che Abdullah, Chihye Lewis Azad, Raquel Ovalle-Robles, Shaoli Fang, Marcio D Lima, Nick J Plant

ACS Appl Mater Interfaces· July 2014

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Fatty acid binding proteins: tissue-specific functions in health and disease.
Alfred E Thumser, Jennifer Bernadette Moore, Nick J Plant

Curr Opin Clin Nutr Metab Care· March 2014

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Optimization of stress response through the nuclear receptor-mediated cortisol signalling network.
Alexey Kolodkin, Nilgun Sahin, Anna Phillips, Steve R Hood, Frank J Bruggeman, Nick Plant

Nat Commun· November 2013

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Non-toxic melanin production inhibitors from Garcinia livingstonei (Clusiaceae).
Dulcie A Mulholland, Elizabeth M Mwangi, Ncoza C Dlova, Nick Plant, Neil R Crouch

J Ethnopharmacol· September 2013

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Site-specific, covalent incorporation of Tus, a DNA-binding protein, on ionic-complementary self-assembling peptide hydrogels using transpeptidase Sortase A as a conjugation tool†Dedicated to the memory of Joachim H. G. Steinke.‡Electronic supplementary information (ESI) available: Further experimental data. See DOI: 10.1039/c3sm00131hClick here for additional data file.
Susanna Piluso, Heather C Cassell, Jonathan L Gibbons, Thomas E Waller, Nick J Plant

Soft Matter· August 2013

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Seizure control by ketogenic diet-associated medium chain fatty acids.
Pishan Chang, Nicole Terbach, Nick Plant, Philip E Chen, Matthew C Walker

Neuropharmacology· June 2013

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The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor.
Ahmad F Abdull Razis, Natalya Hanlon, Ewa Soltys, Veronika Krizova, Renato Iori, Kathryn E Plant, Nick Plant

Arch Toxicol· October 2012

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Characterization of rhodamine-123 as a tracer dye for use in in vitro drug transport assays.
Samantha Forster, Alfred E Thumser, Steve R Hood, Nick Plant

PLoS One· August 2012

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Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner.
Fadheela Al-Salman, Nick Plant

Toxicol Appl Pharmacol· August 2012

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Emergence of the silicon human and network targeting drugs.
Alexey Kolodkin, Fred C Boogerd, Nick Plant, Frank J Bruggeman, Valeri Goncharuk

Eur J Pharm Sci· July 2012

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Probabilistic orthology analysis of the ATP-binding cassette transporters: implications for the development of multiple drug resistance phenotype.
Ciaran Fisher, Tanya Coleman, Nick Plant

Drug Metab Dispos· July 2012

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Characterization of the temporal induction of hepatic xenobiotic-metabolizing enzymes by glucosinolates and isothiocyanates: requirement for at least a 6 h exposure to elicit complete induction profile.
Ahmad F Abdull Razis, Manuela Bagatta, Gina R De Nicola, Renato Iori, Nick Plant

J Agric Food Chem· June 2012

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Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.
Lucy M Elphick, Nadine Pawolleck, Irina A Guschina, Leila Chaieb, Daniel Eikel, Nick J Plant

Dis Model Mech· March 2012

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Phenethyl isothiocyanate, a naturally occurring phytochemical, is an antagonist of the aryl hydrocarbon receptor.
Ahmad F Abdull Razis, Nattaya Konsue, Myrto Dervetzoglou, Kathryn E Plant, Nick Plant

Mol Nutr Food Res· March 2012

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Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon?
David Kavanagh, Isabel Y Pappworth, Holly Anderson, Christine M Hayes, Iain Moore, Nick Plant

Clin J Am Soc Nephrol· March 2012

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The statin class of HMG-CoA reductase inhibitors demonstrate differential activation of the nuclear receptors PXR, CAR and FXR, as well as their downstream target genes.
Katharine Howe, Faizah Sanat, Alfred E Thumser, Tanya Coleman, Nick Plant

Xenobiotica· July 2011

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