Publications by authors named "Nico J Meeuwenoord"

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Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions.
Frank M Speetjens, Marij J P Welters, Marije Slingerland, Mariette I E van Poelgeest, Peggy J de Vos van Steenwijk, Nico J Meeuwenoord

J Immunother Cancer· October 2022

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Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo.
Casper de Boer, Zachary Armstrong, Vincent A J Lit, Uri Barash, Gijs Ruijgrok, Nico J Meeuwenoord

Proc Natl Acad Sci U S A· August 2022

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Chemical synthesis of linear ADP-ribose oligomers up to pentamer and their binding to the oncogenic helicase ALC1.
Qiang Liu, Gunnar Knobloch, Jim Voorneveld, Nico J Meeuwenoord, Herman S Overkleeft

Chem Sci· September 2021

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Molecular Tools for the Study of ADP-Ribosylation: A Unified and Versatile Method to Synthesise Native Mono-ADP-Ribosylated Peptides.
Jim Voorneveld, Johannes Gregor Matthias Rack, Luke van Gijlswijk, Nico J Meeuwenoord, Qiang Liu

Chemistry· July 2021

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Simplified Monopalmitoyl Toll-like Receptor 2 Ligand Mini-UPam for Self-Adjuvanting Neoantigen-Based Synthetic Cancer Vaccines.
Thomas C van den Ende, Jeroen M M Heuts, Geoffroy P P Gential, Marten Visser, Michel J van de Graaff, Nico J Meeuwenoord

Chembiochem· April 2021

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Multivalent, Stabilized Mannose-6-Phosphates for the Targeted Delivery of Toll-Like Receptor Ligands and Peptide Antigens.
Niels R M Reintjens, Elena Tondini, Christopher Vis, Toroa McGlinn, Nico J Meeuwenoord

Chembiochem· January 2021

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Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides.
Niels R M Reintjens, Elena Tondini, Ana R de Jong, Nico J Meeuwenoord, Fabrizio Chiodo

J Med Chem· October 2020

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-Mannosyl Lysine for Solid Phase Assembly of Mannosylated Peptide Conjugate Cancer Vaccines.
Tim P Hogervorst, R J Eveline Li, Laura Marino, Sven C M Bruijns, Nico J Meeuwenoord

ACS Chem Biol· March 2020

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Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen.
Rui-Jun Eveline Li, Tim P Hogervorst, Silvia Achilli, Sven C Bruijns, Tim Arnoldus, Nico J Meeuwenoord

Front Chem· October 2019

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Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells.
Gijs G Zom, Marian M J H P Willems, Nico J Meeuwenoord, Niels R M Reintjens, Elena Tondini

Bioconjug Chem· April 2019

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Amyloid-like Behavior of Site-Specifically Citrullinated Myelin Oligodendrocyte Protein (MOG) Peptide Fragments inside EBV-Infected B-Cells Influences Their Cytotoxicity and Autoimmunogenicity.
Can Araman, Miriam E van Gent, Nico J Meeuwenoord, Nicole Heijmans, Mikkel H S Marqvorsen

Biochemistry· February 2019

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Combined Phosphoramidite-Phosphodiester Reagents for the Synthesis of Methylene Bisphosphonates.
Sander B Engelsma, Nico J Meeuwenoord, Hermen S Overkleeft, Gijsbert A van der Marel, Dmitri V Filippov

Angew Chem Int Ed Engl· March 2017

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TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients.
Gijs G Zom, Marij J P Welters, Nikki M Loof, Renske Goedemans, Sinéad Lougheed, Nico J Meeuwenoord

Oncotarget· October 2016

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Interaction of the amyloid β peptide with sodium dodecyl sulfate as a membrane-mimicking detergent.
Maryam Hashemi Shabestari, Nico J Meeuwenoord, Dmitri V Filippov, Martina Huber

J Biol Phys· June 2016

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Solid-Phase Synthesis of Oligo-ADP-Ribose.
Hans A V Kistemaker, Nico J Meeuwenoord, Herman S Overkleeft, Gijsbert A van der Marel, Dmitri V Filippov

Curr Protoc Nucleic Acid Chem· March 2016

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Bioorthogonal deprotection on the dendritic cell surface for chemical control of antigen cross-presentation.
Joanna B Pawlak, Geoffroy P P Gential, Tracy J Ruckwardt, Jessica S Bremmers, Nico J Meeuwenoord

Angew Chem Int Ed Engl· May 2015

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Synthesis of well-defined adenosine diphosphate ribose oligomers.
Hans A V Kistemaker, Lucien N Lameijer, Nico J Meeuwenoord, Herman S Overkleeft, Gijsbert A van der Marel

Angew Chem Int Ed Engl· April 2015

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Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates.
Gijs G Zom, Selina Khan, Cedrik M Britten, Vinod Sommandas, Marcel G M Camps, Nico J Meeuwenoord

Cancer Immunol Res· August 2014

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Fully automated sequential solid phase approach towards viral RNA-nucleopeptides.
Gerbrand J van der Heden van Noort, Pieter van Delft, Nico J Meeuwenoord, Herman S Overkleeft, Gijsbert A van der Marel

Chem Commun (Camb)· August 2012

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Probing the reactivity of different forms of azurin by flavin photoreduction.
Sharmini Alagaratnam, Nico J Meeuwenoord, José A Navarro, Manuel Hervás, Miguel A De la Rosa

FEBS J· May 2011

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Synthesis of oligoribonucleic acid conjugates using a cyclooctyne phosphoramidite.
Pieter van Delft, Nico J Meeuwenoord, Sascha Hoogendoorn, Jasper Dinkelaar, Herman S Overkleeft

Org Lett· December 2010

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Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG.
Jasper G van den Boorn, Debby Konijnenberg, Esther P M Tjin, Daisy I Picavet, Nico J Meeuwenoord

PLoS One· May 2010

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Phosphine containing oligonucleotides for the development of metallodeoxyribozymes.
Loïc Ropartz, Nico J Meeuwenoord, Gijsbert A van der Marel, Piet W N M van Leeuwen, Alexandra M Z Slawin

Chem Commun (Camb)· April 2007

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Solid-phase synthesis and purification of a set of uniformly 13C, 15N labelled de novo designed membrane fusogenic peptides.
Prashant R Agrawal, Mathias W Hofmann, Nico J Meeuwenoord, Dmitri V Filippov, Holger Stalz

J Pept Sci· February 2007

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Chemical synthesis of picornaviral protein primers of RNA replication.
Nicole M A J Kriek, Nico J Meeuwenoord, Hans van den Elst, Hans A Heus, Gijsbert A van der Marel

Org Biomol Chem· October 2006

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