Publications by authors named "Nicolas Manel"

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Centromeric DNA amplification triggered by viral proteins activates nuclear cGAS.
Xavier Lahaye, Patrick Tran Van, Camellia Chakraborty, Anna Shmakova, Ngoc Tran Bich Cao, Nicolas Manel

Cell· July 2025

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DNA methylation protects cancer cells against senescence.
Xiaoying Chen, Kosuke Yamaguchi, Brianna Rodgers, Delphine Goehrig, David Vindrieux, Nicolas Manel

Nat Commun· July 2025

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Lysosomes in the immunometabolic reprogramming of immune cells in atherosclerosis.
Fabrizia Bonacina, Xiangyu Zhang, Nicolas Manel, Laurent Yvan-Charvet, Babak Razani

Nat Rev Cardiol· March 2025

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Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint.
Solène Hervé, Andrea Scelfo, Gabriele Bersano Marchisio, Marine Grison, Kotryna Vaidžiulytė, Nicolas Manel

Nat Cell Biol· January 2025

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Advancements in pathogen immunity and signaling.
Mads Gyrd-Hansen, Anna Kajaste-Rudnitski, Nicolas Manel, Jan Rehwinkel, Annemarthe G van der Veen

Nat Immunol· August 2024

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Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes.
Zahraa Alraies, Claudia A Rivera, Maria-Graciela Delgado, Doriane Sanséau, Mathieu Maurin, Nicolas Manel

Nat Immunol· July 2024

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Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans.
Samuel D Chauvin, Shoichiro Ando, Joe A Holley, Atsushi Sugie, Fang R Zhao, Nicolas Manel

Nat Commun· June 2024

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Nuclear envelope disruption triggers hallmarks of aging in lung alveolar macrophages.
Nilushi S De Silva, Johan Siewiera, Chantal Alkhoury, Guilherme P F Nader, Francesca Nadalin, Nicolas Manel

Nat Aging· October 2023

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RELA tunes innate-like interferon I/III responses in human T cells.
Nadia Jeremiah, Hermine Ferran, Konstantina Antoniadou, Kevin De Azevedo, Jovan Nikolic, Nicolas Manel

J Exp Med· May 2023

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Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8 T cells in HIV infection.
Mariela P Cabral-Piccin, Laura Papagno, Xavier Lahaye, Federico Perdomo-Celis, Stevenn Volant, Nicolas Manel

EBioMedicine· May 2023

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A druggable copper-signalling pathway that drives inflammation.
Stéphanie Solier, Sebastian Müller, Tatiana Cañeque, Antoine Versini, Arnaud Mansart, Nicolas Manel

Nature· May 2023

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Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria.
Jérémie Rosain, Anna-Lena Neehus, Jérémy Manry, Rui Yang, Jérémie Le Pen, Nicolas Manel

Cell· February 2023

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Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
Tina Schumann, Santiago Costas Ramon, Nadja Schubert, Mohamad Aref Mayo, Melanie Hega, Nicolas Manel

J Exp Med· January 2023

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Selective STING stimulation in dendritic cells primes antitumor T cell responses.
Bakhos Jneid, Aurore Bochnakian, Caroline Hoffmann, Fabien Delisle, Emeline Djacoto, Nicolas Manel

Sci Immunol· January 2023

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Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome.
Mercedes Tkach, Jessie Thalmensi, Eleonora Timperi, Paul Gueguen, Nathalie Névo, Nicolas Manel

Proc Natl Acad Sci U S A· April 2022

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Discovery of Genes that Modulate Flavivirus Replication in an Interferon-Dependent Manner.
Sarah Lesage, Maxime Chazal, Guillaume Beauclair, Damien Batalie, Silvia Cerboni, Nicolas Manel

J Mol Biol· March 2022

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Virus-stimulated Dendritic Cells Elicit a T Antiviral Transcriptional Signature in Human CD4+ Lymphocytes.
Silvia Cerboni, Santy Marques-Ladeira, Nicolas Manel

J Mol Biol· March 2022

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Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion.
Guilherme Pedreira de Freitas Nader, Sonia Agüera-Gonzalez, Fiona Routet, Matthieu Gratia, Mathieu Maurin, Nicolas Manel

Cell· September 2021

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Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics.
Anvita Bhargava, Alice Williart, Mathieu Maurin, Patricia M Davidson, Mabel Jouve, Nicolas Manel

Cell Rep· September 2021

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Single-cell analysis reveals divergent responses of human dendritic cells to the MVA vaccine.
Marius Döring, Kevin De Azevedo, Guillermo Blanco-Rodriguez, Francesca Nadalin, Takeshi Satoh, Nicolas Manel

Sci Signal· August 2021

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Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus.
Federico Cocozza, Nathalie Névo, Ester Piovesana, Xavier Lahaye, Julian Buchrieser, Nicolas Manel

J Extracell Vesicles· December 2020

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Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling.
Alice Lepelley, Maria José Martin-Niclós, Melvin Le Bihan, Joseph A Marsh, Carolina Uggenti, Nicolas Manel

J Exp Med· November 2020

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Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska-Curie innovative training network.
Bernadette van den Hoogen, Angela Santoni, Giuseppe Sciumé, Andrew Bowie, Cliona O'Farrelly, Nicolas Manel

Virus Res· October 2020

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A genetic memory initiates the epigenetic loop necessary to preserve centromere position.
Sebastian Hoffmann, Helena M Izquierdo, Riccardo Gamba, Florian Chardon, Marie Dumont, Nicolas Manel

EMBO J· October 2020

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A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway.
Laurent Zablocki-Thomas, Sam A Menzies, Paul J Lehner, Nicolas Manel, Philippe Benaroch

Innate Immun· August 2020

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