Publications by authors named "Nicolas Thiebaud"

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Multi-laboratory comparisons of manual patch clamp hERG data generated using standardized protocols and following ICH S7B Q&A 2.1 best practices.
Claudia Alvarez Baron, Jun Zhao, Huimei Yu, Ming Ren, Nicolas Thiebaud

Sci Rep· August 2025

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Experimental factors that impact CaV1.2 channel pharmacology-Effects of recording temperature, charge carrier, and quantification of drug effects on the step and ramp currents elicited by the "step-step-ramp" voltage protocol.
Ming Ren, Aaron L Randolph, Claudia Alvarez-Baron, Donglin Guo, Phu N Tran, Nicolas Thiebaud

PLoS One· November 2022

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hERG block potencies for 5 positive control drugs obtained per ICH E14/S7B Q&As best practices: Impact of recording temperature and drug loss.
Claudia Alvarez Baron, Nicolas Thiebaud, Ming Ren, Serge Viatchenko-Karpinski, Amruta Indapurkar

J Pharmacol Toxicol Methods· September 2022

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Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block.
Phu N Tran, Jiansong Sheng, Aaron L Randolph, Claudia Alvarez Baron, Nicolas Thiebaud

PLoS One· December 2020

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A unique olfactory bulb microcircuit driven by neurons expressing the precursor to glucagon-like peptide 1.
Nicolas Thiebaud, Fiona Gribble, Frank Reimann, Stefan Trapp, Debra Ann Fadool

Sci Rep· October 2019

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Loss of odor-induced c-Fos expression of juxtaglomerular activity following maintenance of mice on fatty diets.
Erminia Fardone, Arda B Celen, Nicholas A Schreiter, Nicolas Thiebaud, Melissa L Cooper

J Bioenerg Biomembr· February 2019

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Elevated Anxiety and Impaired Attention in Super-Smeller, Kv1.3 Knockout Mice.
Zhenbo Huang, Carlie A Hoffman, Brandon M Chelette, Nicolas Thiebaud, Debra A Fadool

Front Behav Neurosci· March 2018

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Differential serotonergic modulation across the main and accessory olfactory bulbs.
Zhenbo Huang, Nicolas Thiebaud, Debra Ann Fadool

J Physiol· June 2017

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Neuromodulation in Chemosensory Pathways.
Jeremy C McIntyre, Nicolas Thiebaud, John P McGann, Takaki Komiyama, Markus Rothermel

Chem Senses· June 2017

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The incretin hormone glucagon-like peptide 1 increases mitral cell excitability by decreasing conductance of a voltage-dependent potassium channel.
Nicolas Thiebaud, Ida J Llewellyn-Smith, Fiona Gribble, Frank Reimann, Stefan Trapp

J Physiol· May 2016

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Hyperlipidemic diet causes loss of olfactory sensory neurons, reduces olfactory discrimination, and disrupts odor-reversal learning.
Nicolas Thiebaud, Melissa C Johnson, Jessica L Butler, Genevieve A Bell, Kassandra L Ferguson

J Neurosci· May 2014

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Odorant metabolism catalyzed by olfactory mucosal enzymes influences peripheral olfactory responses in rats.
Nicolas Thiebaud, Stéphanie Veloso Da Silva, Ingrid Jakob, Gilles Sicard, Joëlle Chevalier

PLoS One· September 2013

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Odorant-binding proteins and xenobiotic metabolizing enzymes: implications in olfactory perireceptor events.
Jean-Marie Heydel, Alexandra Coelho, Nicolas Thiebaud, Arièle Legendre, Anne-Marie Le Bon

Anat Rec (Hoboken)· September 2013

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Glucose sensitivity of mouse olfactory bulb neurons is conveyed by a voltage-gated potassium channel.
Kristal Tucker, Sukhee Cho, Nicolas Thiebaud, Michael X Henderson, Debra Ann Fadool

J Physiol· May 2013

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Olfactory ability and object memory in three mouse models of varying body weight, metabolic hormones, and adiposity.
Kristal R Tucker, Steven J Godbey, Nicolas Thiebaud, Debra Ann Fadool

Physiol Behav· October 2012

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Expression and differential localization of xenobiotic transporters in the rat olfactory neuro-epithelium.
Nicolas Thiebaud, Franck Menetrier, Christine Belloir, Anne-Laure Minn, Fabrice Neiers

Neurosci Lett· November 2011

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Effects of typical inducers on olfactory xenobiotic-metabolizing enzyme, transporter, and transcription factor expression in rats.
Nicolas Thiebaud, Maud Sigoillot, Joëlle Chevalier, Yves Artur, Jean-Marie Heydel

Drug Metab Dispos· October 2010

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UDP-glucuronosyltransferases (UGTs) in neuro-olfactory tissues: expression, regulation, and function.
Jean-Marie Heydel, Elzbieta J Holsztynska, Arièle Legendre, Nicolas Thiebaud, Yves Artur

Drug Metab Rev· February 2010

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