Publications by authors named "Nicole Mutter"

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Computationally guided optimization of the antimalarial activity and physicochemical properties of 2,4-diaminopyrimidines.
Guntur Guntur, Duangkamol Gleeson, Mark Anderson, Nicole Mutter, Lauren Webster

RSC Med Chem· August 2025

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Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of .
Simon R Green, Justin R Harrison, Stephen Thompson, Dinakaran Murugesan, M Daben J Libardo, Nicole Mutter

ACS Infect Dis· March 2025

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lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.
Nicola Caldwell, Caroline Peet, Peter Miller, Beatrice L Colon, Malcolm G Taylor, Nicole Mutter

Sci Transl Med· October 2024

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Superior Anticancer and Antifungal Activities of New Sulfanyl-Substituted Niclosamide Derivatives.
Jingyi Ma, Dileepkumar Veeragoni, Hindole Ghosh, Nicole Mutter, Gisele Barbosa

Biomedicines· July 2024

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Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism.
A Kenneth MacLeod, Kevin-Sebastien Coquelin, Leticia Huertas, Frederick R C Simeons, Jennifer Riley, Nicole Mutter

Proc Natl Acad Sci U S A· February 2024

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Structure-Guided Design and Synthesis of a Pyridazinone Series of Proteasome Inhibitors.
Michael G Thomas, Kate McGonagle, Paul Rowland, David A Robinson, Peter G Dodd, Nicole Mutter

J Med Chem· August 2023

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Preparation, biological evaluation and QSAR analysis of urea substituted 2,4-diamino-pyrimidine anti-malarials.
Borvornwat Toviwek, Jennifer Riley, Nicole Mutter, Mark Anderson, Lauren Webster

RSC Med Chem· December 2022

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Potent antiplasmodial alkaloids from the rhizobacterium Pantoea agglomerans as hemozoin modulators.
Bathini Thissera, Irene Hallyburton, Che Julius Ngwa, Hafsa Cherif-Silini, Ahmed S I Hassane, Nicole Mutter

Bioorg Chem· October 2021

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Preparation, biological & cheminformatics-based assessment of N,N-diphenylpyrimidine-2,4-diamine as potential Kinase-targeted antimalarials.
Borvornwat Toviwek, Oraphan Phuangsawai, Adchatawut Konsue, Supa Hannongbua, Jennifer Riley, Nicole Mutter

Bioorg Med Chem· September 2021

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Pembrolizumab in a Patient With a Metastatic CASTLE Tumor of the Parotid.
Lisa Lorenz, Joscha von Rappard, Walter Arnold, Nicole Mutter, Udo Schirp

Front Oncol· August 2019

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Anti-angiogenic therapies in cancer: achievements and open questions.
Curzio Ruegg, Nicole Mutter

Bull Cancer· September 2007

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Temozolomide: a milestone in neuro-oncology and beyond?
Nicole Mutter, Roger Stupp

Expert Rev Anticancer Ther· August 2006

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