Publications by authors named "Niefang Yu"

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Minor structural modifications to Pracinostat produce big changes in its biological responses.
Rong Jia, Pengju Sun, Yan Zhang, Youjin Ge, Niefang Yu

Chem Biol Drug Des· August 2019

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A new sarkomycin analog from Streptomyces sp. HS-HY-144.
Li-fei Liu, Huan Qi, Hui Zhang, Ji-dong Wang, Nie-fang Yu

J Antibiot (Tokyo)· December 2015

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Macrocyclic compounds as anti-cancer agents: design and synthesis of multi-acting inhibitors against HDAC, FLT3 and JAK2.
Cheng-Qing Ning, Cheng Lu, Liang Hu, Yan-Jing Bi, Lei Yao, Yu-Jun He, Xiao-Yu Liu, Nie-Fang Yu

Eur J Med Chem· May 2015

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Design, synthesis and biological evaluation of di-substituted cinnamic hydroxamic acids bearing urea/thiourea unit as potent histone deacetylase inhibitors.
Chengqing Ning, Yanjing Bi, Yujun He, WenYuan Huang, Lifei Liu, Xiaoyu Liu, Niefang Yu

Bioorg Med Chem Lett· December 2013

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Design, synthesis and biological evaluation of indeno[1,2-d]thiazole derivatives as potent histone deacetylase inhibitors.
Ming Zhou, Chengqing Ning, Ruihuan Liu, Yujun He, Niefang Yu

Bioorg Med Chem Lett· June 2013

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[Research progresses of the PARP inhibitors for the treatment of cancer].
Yu-Jun He, Rui-Huan Liu, Cheng-Qing Ning, Nie-Fang Yu

Yao Xue Xue Bao· May 2013

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Discovery and mechanism study of SIRT1 activators that promote the deacetylation of fluorophore-labeled substrate.
Jiahui Wu, Dengyou Zhang, Lei Chen, Jianneng Li, Jianling Wang, Niefang Yu

J Med Chem· February 2013

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Discovery of (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profile.
Haishan Wang, Niefang Yu, Dizhong Chen, Ken Chi Lik Lee, Pek Ling Lye

J Med Chem· July 2011

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[Structure-activity relationships of histone deacetylase inhibitors].
Yu-Mei Tan, Wen-Yuan Huang, Nie-Fang Yu

Yao Xue Xue Bao· October 2009

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N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: design, synthesis, SAR studies, and in vivo antitumor activity.
Haishan Wang, Niefang Yu, Hongyan Song, Dizhong Chen, Yong Zou

Bioorg Med Chem Lett· March 2009

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[The signal transduction pathway of multi-target kinase inhibitors as anticancer agents in clinical use or in phase III].
Wen Wu, Cheng Lu, Si-yu Chen, Nie-fang Yu

Yao Xue Xue Bao· March 2009

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Anticancer drug discovery targeting DNA hypermethylation.
Niefang Yu, Mingrong Wang

Curr Med Chem· August 2008

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