Publications by authors named "Niels A D Guchelaar"

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Phase I study of intraperitoneal irinotecan with systemic capecitabine and oxaliplatin for patients with gastric peritoneal metastases.
Niels A D Guchelaar, Marion W Tops-Welten, Pieter C van der Sluis, Bo J Noordman, Stijn L W Koolen

Biomed Pharmacother· October 2025

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Staging laparoscopy for gastric cancer: European consensus.
Sander J M van Hootegem, Niels A D Guchelaar, Karen van der Sluis, Lianne Triemstra, Stefan P Mönig

Br J Surg· September 2025

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A Clinical Pharmacological Perspective on Intraperitoneal Chemotherapy.
Pascale C S Rietveld, Niels A D Guchelaar, Sebastiaan D T Sassen, Birgit C P Koch, Ron H J Mathijssen

Drugs· July 2025

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Pharmacokinetic boosting of olaparib: Study protocol of a multicentre, open-label, randomised, non-inferiority trial (PROACTIVE-B).
Joanneke K Overbeek, Niels A D Guchelaar, Ma Ida Mohmaed Ali, Muriëlle Sark, Carolien Hovenier

Contemp Clin Trials Commun· June 2025

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The prognostic value of peritoneal metastases in patients with gastric cancer: a nationwide population-based study.
Niels A D Guchelaar, Micha J de Neijs, Bo J Noordman, Heilida E C Graaf, Irene E G van Hellemond

EClinicalMedicine· March 2025

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Trifluridine-tipiracil in previously treated patients with oestrogen receptor-positive, HER2-negative metastatic breast cancer (BOOG 2019-01 TIBET trial): a single-arm, multicentre, phase 2 trial.
Niels A D Guchelaar, Ron H J Mathijssen, Maaike de Boer, Marlies L van Bekkum, Joan B Heijns

EClinicalMedicine· February 2025

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Therapeutic Drug Monitoring of Oral Oncology Drugs: Finding the Right Nails.
Niels A D Guchelaar, Maud B A van der Kleij, Neeltje Steeghs, Alwin D R Huitema, Ron H J Mathijssen

Clin Pharmacol Ther· September 2024

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Reasons for non-feasibility of therapeutic drug monitoring of oral targeted therapies in oncology - an analysis of the closed cohorts of a multicentre prospective study.
Maud B A van der Kleij, Niels A D Guchelaar, Marinda Meertens, Kim Westerdijk, Eline L Giraud

Br J Cancer· September 2024

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Intraperitoneal pharmacokinetics of systemic oxaliplatin, 5-fluorouracil and bevacizumab in patients with colorectal peritoneal metastases.
Pascale C S Rietveld, Niels A D Guchelaar, Ruben A G van Eerden, Nadine L de Boer, Peter de Bruijn

Biomed Pharmacother· July 2024

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The OCT2/MATE1 Interaction Between Trifluridine, Metformin and Cimetidine: A Crossover Pharmacokinetic Study.
Niels A D Guchelaar, Stefan A J Buck, Leni van Doorn, Koen G A M Hussaarts, Yorick Sandberg

Clin Pharmacokinet· July 2024

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Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort.
Marinda Meertens, Eline L Giraud, Maud B A van der Kleij, Kim Westerdijk, Niels A D Guchelaar

Clin Pharmacokinet· July 2024

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Systemic Treatment Strategies and Outcomes of Patients With Synchronous Peritoneal Metastases of Gastric Origin: A Nationwide Population-Based Study.
Niels A D Guchelaar, Bo J Noordman, Marion W Welten, Myron T van Santen, Micha J de Neijs

J Natl Compr Canc Netw· July 2024

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Staging laparoscopy in gastric cancer patients: From a Dutch nationwide Delphi consensus towards a standardized protocol.
Karen van der Sluis, Niels A D Guchelaar, Lianne Triemstra, Ron H J Mathijssen, Jelle P Ruurda

Eur J Surg Oncol· June 2024

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Population pharmacokinetics of intraperitoneal irinotecan and SN-38 in patients with peritoneal metastases from colorectal origin.
Pascale C S Rietveld, Sebastiaan D T Sassen, Niels A D Guchelaar, Ruben A G van Eerden, Nadine L de Boer

CPT Pharmacometrics Syst Pharmacol· June 2024

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Intraperitoneal chemotherapy for peritoneal metastases of gastric origin: a systematic review and meta-analysis.
Niels A D Guchelaar, Kazem Nasserinejad, Bianca Mostert, Stijn L W Koolen, Pieter C van der Sluis

Br J Surg· May 2024

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Intraperitoneal irinotecan with concomitant FOLFOX and bevacizumab for patients with unresectable colorectal peritoneal metastases: protocol of the multicentre, open-label, phase II, INTERACT-II trial.
Vincent C J van de Vlasakker, Niels A D Guchelaar, Teun B M van den Heuvel, Robin J Lurvink, Esther van Meerten

BMJ Open· January 2024

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Pharmacokinetic boosting of olaparib: A randomised, cross-over study (PROACTIVE-study).
Joanneke K Overbeek, Niels A D Guchelaar, Ma Ida Mohmaed Ali, Petronella B Ottevanger, Haiko J Bloemendal

Eur J Cancer· November 2023

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Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology.
Maud B A van der Kleij, Niels A D Guchelaar, Ron H J Mathijssen, Jurjen Versluis, Alwin D R Huitema

Clin Pharmacokinet· October 2023

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CYP3A4*22 Genotype-Guided Dosing of Kinase Inhibitors in Cancer Patients.
Ruben A G van Eerden, Nikki S IJzerman, Milan van Meekeren, Esther Oomen-de Hoop, Niels A D Guchelaar

Clin Pharmacokinet· August 2023

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COVID-19 Incidence and Disease Course Among Patients at an Allergy Department.
Louise E van der Aa, Inge S van Egmond, Martijn van der Sluijs, A A Sophie den Otter, Nadie H M Bosmans, Niels A D Guchelaar

Ther Adv Allergy Rhinol· May 2023

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Intraperitoneal Chemotherapy for Unresectable Peritoneal Surface Malignancies.
Niels A D Guchelaar, Bo J Noordman, Stijn L W Koolen, Bianca Mostert, Eva V E Madsen

Drugs· February 2023

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Influence of Darolutamide on Cabazitaxel Systemic Exposure.
Stefan A J Buck, Niels A D Guchelaar, Peter de Bruijn, Inge M Ghobadi Moghaddam-Helmantel, Esther Oomen-de Hoop

Clin Pharmacokinet· October 2022

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Feasibility of therapeutic drug monitoring of sorafenib in patients with liver or thyroid cancer.
Niels A D Guchelaar, Ruben A G van Eerden, Stefanie L Groenland, Leni van Doorn, Ingrid M E Desar

Biomed Pharmacother· September 2022

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Intraperitoneal paclitaxel for patients with primary malignant peritoneal mesothelioma: a phase I/II dose escalation and safety study-INTERACT MESO.
Job P van Kooten, Michelle V Dietz, Niels A D Guchelaar, Alexandra R M Brandt-Kerkhof, Stijn L W Koolen

BMJ Open· June 2022

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Characteristics of COVID-19 infection and antibody formation in patients known at a tertiary immunology department.
Niels A D Guchelaar, Jan A M van Laar, Maud A W Hermans, Tim B van der Houwen, Sibel Atmaca

J Transl Autoimmun· January 2021

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