Publications by authors named "Nigam Kumar"

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Simulating cellular galectin networks by mixing galectins in vitro reveals synergistic activity.
Ruud P M Dings, Nigam Kumar, Sterling Mikkelson, Hans-Joachim Gabius, Kevin H Mayo

Biochem Biophys Rep· December 2021

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PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy.
Pottayil G Sasikumar, Naremaddepalli S Sudarshan, Srinivas Adurthi, Raghuveer K Ramachandra, Dodderi S Samiulla, Nigam Kumar

Commun Biol· June 2021

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Reversible re-programing of cell-cell interactions.
Kari Gabrielse, Amit Gangar, Nigam Kumar, Jae Chul Lee, Adrian Fegan

Angew Chem Int Ed Engl· May 2014

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Structure-based optimization of angiostatic agent 6DBF7, an allosteric antagonist of galectin-1.
Ruud P M Dings, Nigam Kumar, Michelle C Miller, Melissa Loren, Huzaifa Rangwala

J Pharmacol Exp Ther· March 2013

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Protein lysine-Nζ alkylation and O-phosphorylation mediated by DTT-generated reactive oxygen species.
Nigam Kumar, Hans Ippel, Christian Weber, Tilman Hackeng, Kevin H Mayo

Protein Sci· March 2013

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Antitumor agent calixarene 0118 targets human galectin-1 as an allosteric inhibitor of carbohydrate binding.
Ruud P M Dings, Michelle C Miller, Irina Nesmelova, Lucile Astorgues-Xerri, Nigam Kumar

J Med Chem· June 2012

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Crystallographically observed folded topology of an unsubstituted γ-aminobutyric acid incorporated in a model peptide: importance of a C--H···O interaction.
Nigam Kumar, Paloth Venugopalan, Raghuvansh Kishore

Biopolymers· November 2010

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Determination of an unusual secondary structural element in the immunostimulating tetrapeptide rigin in aqueous environments: insights via MD simulations, (1)H NMR and CD spectroscopic studies.
Nigam Kumar, Raghuvansh Kishore

J Pept Sci· September 2010

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