Publications by authors named "Nigel J Coates"

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Diversity oriented biosynthesis via accelerated evolution of modular gene clusters.
Aleksandra Wlodek, Steve G Kendrew, Nigel J Coates, Adam Hold, Joanna Pogwizd

Nat Commun· October 2017

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Recombinant strains for the enhanced production of bioengineered rapalogs.
Steven G Kendrew, Hrvoje Petkovic, Sabine Gaisser, Sarah J Ready, Matthew A Gregory, Nigel J Coates

Metab Eng· January 2013

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Preclinical characterization of naturally occurring polyketide cyclophilin inhibitors from the sanglifehrin family.
Matthew A Gregory, Michael Bobardt, Susan Obeid, Udayan Chatterji, Nigel J Coates

Antimicrob Agents Chemother· May 2011

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Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate.
Jennifer N Andexer, Steven G Kendrew, Mohammad Nur-e-Alam, Orestis Lazos, Teresa A Foster, Nigel J Coates

Proc Natl Acad Sci U S A· March 2011

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Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.
Ming-Qiang Zhang, Sabine Gaisser, Mohammad Nur-E-Alam, Lesley S Sheehan, William A Vousden, Nigel J Coates

J Med Chem· September 2008

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