Publications by authors named "Nigel Webster"

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Dose assessment of melatonin in sepsis (DAMSEL2) study: Pharmacokinetics of two doses of oral melatonin in patients with sepsis.
Helen F Galley, Lee Allen, Pieter J Colin, Sally P Galt, Nigel R Webster

J Pineal Res· November 2022

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An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression.
Eddie Cano-Gamez, Katie L Burnham, Cyndi Goh, Alice Allcock, Zunaira H Malick, Nigel Webster

Sci Transl Med· November 2022

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Melatonin Is a Feasible, Safe, and Acceptable Intervention in Doctors and Nurses Working Nightshifts: The MIDNIGHT Trial.
Bensita M V J Thottakam, Nigel R Webster, Lee Allen, Malachy O Columb, Helen F Galley

Front Psychiatry· August 2020

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Reply to Comment on "Differential Effects of MitoVitE, α-Tocopherol and Trolox on Oxidative Stress, Mitochondrial Function and Inflammatory Signalling Pathways in Endothelial Cells Cultured under Conditions Mimicking Sepsis. 2020, (3), 195".
Beverley E Minter, Damon A Lowes, Nigel R Webster, Helen F Galley

Antioxidants (Basel)· June 2020

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Differential Effects of MitoVitE, α-Tocopherol and Trolox on Oxidative Stress, Mitochondrial Function and Inflammatory Signalling Pathways in Endothelial Cells Cultured under Conditions Mimicking Sepsis.
Beverley E Minter, Damon A Lowes, Nigel R Webster, Helen F Galley

Antioxidants (Basel)· February 2020

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Delirium screening in the intensive care unit using emerging QEEG techniques: A pilot study.
Andrew Hunter, Barry Crouch, Nigel Webster, Bettina Platt

AIMS Neurosci· January 2020

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Deep anaesthesia and poor outcomes: the jury is still out.
Helen F Galley, Nigel R Webster

Lancet· November 2019

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Brief isoflurane anaesthesia affects differential gene expression, gene ontology and gene networks in rat brain.
Damon A Lowes, Helen F Galley, Alessandro P S Moura, Nigel R Webster

Behav Brain Res· January 2017

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Characterisation of gamma delta (γδ) T cell populations in patients with sepsis.
Helen F Galley, Damon A Lowes, Keith Thompson, Naomi D Wilson, Carol A Wallace, Nigel R Webster

Cell Biol Int· February 2015

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Melatonin as a potential therapy for sepsis: a phase I dose escalation study and an ex vivo whole blood model under conditions of sepsis.
Helen F Galley, Damon A Lowes, Lee Allen, Gary Cameron, Lorna S Aucott, Nigel R Webster

J Pineal Res· May 2014

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Clinical application of sepsis biomarkers.
Vinoth Sankar, Nigel R Webster

J Anesth· April 2013

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Dehydroascorbic acid as pre-conditioner: protection from lipopolysaccharide induced mitochondrial damage.
Damon A Lowes, Nigel R Webster, Helen F Galley

Free Radic Res· March 2010

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The mitochondria targeted antioxidant MitoQ protects against fluoroquinolone-induced oxidative stress and mitochondrial membrane damage in human Achilles tendon cells.
Damon A Lowes, Carol Wallace, Michael P Murphy, Nigel R Webster, Helen F Galley

Free Radic Res· April 2009

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The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis.
Damon A Lowes, Bensita M V Thottakam, Nigel R Webster, Michael P Murphy, Helen F Galley

Free Radic Biol Med· December 2008

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Polymorphism in the manganese superoxide dismutase gene.
Noha E Elsakka, Nigel R Webster, Helen F Galley

Free Radic Res· July 2007

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Production of soluble triggering receptor expressed on myeloid cells by lipopolysaccharide-stimulated human neutrophils involves de novo protein synthesis.
Amr M Mahdy, Damon A Lowes, Helen F Galley, Jane E Bruce, Nigel R Webster

Clin Vaccine Immunol· April 2006

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Opportunities to replace the use of animals in sepsis research. The report and recommendations of a Focus on Alternatives workshop.
Chris Langley, Chris Brock, Gerard Brouwer, Alun Brown, Lucie Clapp, Nigel Webster

Altern Lab Anim· December 2005

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Selective phosphodiesterase 5 inhibition does not reduce propofol sedation requirements but affects speed of recovery and plasma cyclic guanosine 3',5'-monophosphate concentrations in healthy volunteers.
Thomas Engelhardt, Jamie MacDonald, Helen F Galley, Nigel R Webster

Anesth Analg· October 2005

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Differential effects of three antibiotics on T helper cell cytokine expression.
Auriol C Williams, Helen F Galley, Alison M Watt, Nigel R Webster

J Antimicrob Chemother· September 2005

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A microarray analysis of potential genes underlying the neurosensitivity of mice to propofol.
Damon A Lowes, Helen F Galley, Peter R Lowe, Brad A Rikke, Thomas E Johnson, Nigel R Webster

Anesth Analg· September 2005

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The effect of N-acetylcysteine on nuclear factor-kappa B activation, interleukin-6, interleukin-8, and intercellular adhesion molecule-1 expression in patients with sepsis.
Ross L Paterson, Helen F Galley, Nigel R Webster

Crit Care Med· November 2003

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Influence of interleukin-10 polymorphisms on interleukin-10 expression and survival in critically ill patients.
Peter R Lowe, Helen F Galley, Ashraf Abdel-Fattah, Nigel R Webster

Crit Care Med· January 2003

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Inflammation and the coagulation system.
Nigel R Webster

Br J Anaesth· August 2002

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Increased bone resorption in the critically ill: association with sepsis and increased nitric oxide production.
Lorna M Smith, Brian Cuthbertson, John Harvie, Nigel Webster, Simon Robins

Crit Care Med· April 2002

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