Publications by authors named "Nikolaos P Daskalakis"

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Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation.
Rachel Yehuda, Nikolaos P Daskalakis, Linda M Bierer, Heather N Bader, Torsten Klengel, Florian Holsboer, Elisabeth B Binder

Biol Psychiatry· September 2016

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Astrocytic glutamate regulation is shaped by adversity and glucocorticoid signalling.
Dominic Kaul, Amber R Curry, Nathalie Gerstner, Anna S Fröhlich, Anthi C Krontira, Nikolaos P Daskalakis

bioRxiv· September 2025

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Corticosteroid-regulated gene transcription in SH-SY5Y-derived neurons: Insights into the mineralocorticoid and glucocorticoid receptor-mediated response.
Justina F Lugenbühl, Clara Snijders, Cameron D Pernia, Marina Soliva Estruch, Gunter Kenis, Nikolaos P Daskalakis

J Neuroendocrinol· July 2025

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Stress Molecular Signaling in Interaction With Cognition.
Justina F Lugenbühl, Eva M G Viho, Elisabeth B Binder, Nikolaos P Daskalakis

Biol Psychiatry· February 2025

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How Can Early Stress Influence Later Alzheimer's Disease Risk? Possible Mediators and Underlying Mechanisms.
Paul J Lucassen, Aniko Korosi, Susanne R de Rooij, August B Smit, Anne-Marie Van Dam, Nikolaos P Daskalakis

Biol Psychiatry· February 2025

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Stress and Cognition: From Bench to Bedside?
Lars Schwabe, Nikolaos P Daskalakis

Biol Psychiatry· February 2025

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Brain dynamics reflecting an intra-network brain state is associated with increased posttraumatic stress symptoms in the early aftermath of trauma.
Mohammad Se Sendi, Zening Fu, Nathaniel G Harnett, Sanne J H van Rooij, Victor Vergara, Nikolaos P Daskalakis

Nat Ment Health· February 2025

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Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts.
Seyma Katrinli, Agaz H Wani, Adam X Maihofer, Andrew Ratanatharathorn, Nikolaos P Daskalakis

Genome Med· December 2024

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SKA2 enhances stress-related glucocorticoid receptor signaling through FKBP4-FKBP5 interactions in neurons.
Jakob Hartmann, Claudia Klengel, Larissa J Dillmann, Erin E Hisey, Kathrin Hafner, Nikolaos P Daskalakis

Proc Natl Acad Sci U S A· December 2024

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Single-nucleus transcriptomic profiling of human orbitofrontal cortex reveals convergent effects of aging and psychiatric disease.
Anna S Fröhlich, Nathalie Gerstner, Miriam Gagliardi, Maik Ködel, Natan Yusupov, Nikolaos P Daskalakis

Nat Neurosci· October 2024

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Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.
Agaz H Wani, Seyma Katrinli, Xiang Zhao, Nikolaos P Daskalakis, Anthony S Zannas

BMC Med Genomics· September 2024

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Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohorts.
Seyma Katrinli, Agaz H Wani, Adam X Maihofer, Andrew Ratanatharathorn, Nikolaos P Daskalakis

medRxiv· July 2024

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Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.
Caroline M Nievergelt, Adam X Maihofer, Elizabeth G Atkinson, Chia-Yen Chen, Karmel W Choi, Nikolaos P Daskalakis

Nat Genet· May 2024

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Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain.
Cindy Wen, Michael Margolis, Rujia Dai, Pan Zhang, Pawel F Przytycki, Nikolaos P Daskalakis

Science· May 2024

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Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood.
Nikolaos P Daskalakis, Artemis Iatrou, Chris Chatzinakos, Aarti Jajoo, Clara Snijders

Science· May 2024

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No Replication of Alzheimer's Disease Genetics as a Moderator of Combat Exposure's Association with PTSD risk in 138,592 Combat Veterans.
Erika J Wolf, Mark W Miller, Rui Zhang, Richard Sherva, Kelly M Harrington, Nikolaos P Daskalakis

Nat Ment Health· April 2024

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Unraveling the cell-type-specific molecular pathways of PTSD: integrating GWAS with brain genomic profiling and in vitro modeling.
Artemis Iatrou, Nikolaos P Daskalakis

Neuropsychopharmacology· January 2024

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Genetic architecture distinguishes tinnitus from hearing loss.
Royce E Clifford, Adam X Maihofer, Chris Chatzinakos, Jonathan R I Coleman, Nikolaos P Daskalakis

Nat Commun· January 2024

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Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.
Chris Chatzinakos, Cameron D Pernia, Filomene G Morrison, Artemis Iatrou, Kenneth M McCullough, Nikolaos P Daskalakis

Am J Psychiatry· October 2023

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Allostatic load in early adolescence: gene / environment contributions and relevance for mental health.
Kevin W Hoffman, Kate T Tran, Tyler M Moore, Mārtiņš M Gataviņš, Elina Visoki, Nikolaos P Daskalakis

medRxiv· October 2023

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Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders.
Caroline M Nievergelt, Adam X Maihofer, Elizabeth G Atkinson, Chia-Yen Chen, Karmel W Choi, Nikolaos P Daskalakis

medRxiv· September 2023

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Circulating PACAP levels are associated with increased amygdala-default mode network resting-state connectivity in posttraumatic stress disorder.
Kevin J Clancy, Quentin Devignes, Poornima Kumar, Victor May, Sayamwong E Hammack, Nikolaos P Daskalakis

Neuropsychopharmacology· July 2023

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Genetics and epigenetics of stress: New avenues for an old concept.
Marina Soliva-Estruch, Kellie L Tamashiro, Nikolaos P Daskalakis

Neurobiol Stress· March 2023

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modeling of the neurobiological effects of glucocorticoids: A review.
Katherine Bassil, Anthi C Krontira, Thomas Leroy, Alana I H Escoto, Clara Snijders, Nikolaos P Daskalakis

Neurobiol Stress· March 2023

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Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.
Cindy Wen, Michael Margolis, Rujia Dai, Pan Zhang, Pawel F Przytycki, Nikolaos P Daskalakis

medRxiv· March 2023

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