PubHawk
Biol Psychiatry September 2016 PMID 26410355

Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation.

Rachel Yehuda, Nikolaos P Daskalakis, Linda M Bierer, Heather N Bader, Torsten Klengel, Florian Holsboer, Elisabeth B Binder

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Mentions

226
Peak: 18 in Mar 2024
across 6 sources since Oct 2019

Extended reach

763,923
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Total likes

900

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Oct 2019 – Jun 2025

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AI synopsis

What people are saying

The discussions reflect a shared recognition of the study's importance, exemplified by mentions of trauma transmission and epigenetic changes affecting genes like FKBP5. Words such as 'powerful,' 'impact,' and questions about whether these inherited effects can be passed down demonstrate a mix of curiosity and acknowledgment of the study's significance without deep technical analysis.

AgreementModerate agreement

Most comments acknowledge the significance of the study, with some questioning its implications or expressing curiosity, indicating general support with some skepticism.

InterestModerate interest

Discussions show mild to moderate interest, as posts mention the emotional and scientific aspects but do not delve deeply into technical details.

EngagementModerate engagement

Users reference specific concepts like epigenetics and intergenerational trauma, suggesting a moderate level of engagement, though some responses are brief or superficial.

ImpactModerate impact

The overall tone suggests the discussion recognizes the study's potential influence on understanding trauma, but mostly at a conceptual level without detailed exploration of societal impacts.

Abstract in brief

  • The study found that Holocaust exposure affected the methylation (a type of epigenetic change) of the FKBP5 gene not only in survivors but also in their children, suggesting intergenerational effects of trauma.
  • Different methylation sites within the FKBP5 gene were linked to parental trauma and the children's own childhood abuse, indicating site-specific environmental influences.
  • Changes in FKBP5 methylation were related to cortisol levels, showing that these epigenetic modifications have potential functional impacts on stress regulation and could explain how trauma effects are transmitted across generations.]
Read the full abstract

Top posts

Most liked on X and Bluesky
نواف العثمان
@Nawaf_i · X

بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 82 likes · 19 shares · 35,775 followers View post →
Xiskya ن
@xiskya · X

La guerra tiene efectos Intergeneracionales. No solo por el relato verbal de lo sucedido. Las guerrearás impactan sobre las capas químicas de los cromosomas, transmitiendo el dolor a través de la memoria biológica. Afectan al gen FKBP5. Fuente del estudio: https://t.co/dK08BtnEdu https://t.co/dfYYsGFBmU

May 2, 2022 · 9 likes · 5 shares · 77,933 followers View post →
Graham Pechenik
@graham_pechenik · X

@MichaelHaichin @RussellHausfeld @smacdonald10 @JD_Rosenblat FKBP5 is also implicated in intergenerational trauma: Holocaust survivors and their adult offspring have epigenetic changes on the same region of that gene https://t.co/vc08hA4aHG https://t.co/cZAUaOBKny https://t.co/4FuDoFYf5R

Jan 14, 2021 · 2 likes · 5,677 followers View post →
Dr. Courtney "got vaccinated" Wilder
@wilder_courtney · X

@mbbrownlee The journal is Biological Psychiatry; title of the article is Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation; date and link: September 1, 2016; 80:372–380 https://t.co/QU7RQdaqUN Some of the science went over my head but the findings were powerful.

Nov 17, 2019 · 2 likes · 914 followers View post →
Kriter Kurumsal Eğitim ve Danışmanlık
@KriterEgitim · X

Sahip olduğumuz ruhsal sıkıntılar acaba atalarımızdan bize miras olarak aktarılmış olabilir mi? Geçmiş nesilde yaşanan travmatik olayların izleri, nesilden nesile aktarılabilir mi?

Sep 1, 2021 · 2 likes · 1 share · 96 followers View post →
1yl
@1yl · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 24, 2024 · 19 shares · 586,811 followers View post →

All mentions

Average Trucker
@BuckedUnicorn · X

@Grimezsz You might be on to something. Here is a study on "The Holocaust survivor study on epigenetic changes and the transmission of trauma to children" https://t.co/LmZa2iAJna

Apr 5, 2025 · 491 followers View post →
1yl
@1yl · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 24, 2024 · 19 shares · 586,811 followers View post →
ＳＡＲＡＨ
@sara200985 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 20, 2024 · 19 shares · 751 followers View post →
Bedria Al-Is'haq ▶️
@alishaqb · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 20, 2024 · 19 shares · 624 followers View post →
Benoualha Atman ⚓
@AtmanBenoualha · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 20, 2024 · 19 shares · 52 followers View post →
h95379881
@h95379881 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 136 followers View post →
Aseel 369 ❤
@AcylCream · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 78 followers View post →
Nabi
@Na_bi_369 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 61 followers View post →
Ghadah
@Ghadah8899 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 170 followers View post →
احمد
@azYPfsFhkHbhC7H · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 97 followers View post →
⚜️
@fortina759 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 39 followers View post →
Hanan
@Hanan3655 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 22 followers View post →
ًٍّ مــيــــدو ًٍّ
@tote43 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 102 followers View post →
عيشُُ رغيد
@amal67135967 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 57 followers View post →
Syraa
@_saroz3 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 1,366 followers View post →
NEHAD
@NEHADO10 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 206 followers View post →
تهاني
@TahaniMahmoud1 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 137 followers View post →
شُروقْ الحربي |
@shro0oq11 · X

RT @Nawaf_i: بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 19 shares · 9,754 followers View post →
نواف العثمان
@Nawaf_i · X

بعض صدماتك و مخاوفك قد تكون مورثة لك المصدر https://t.co/4qW4NWpxLq https://t.co/zguqtWKAD7

Mar 19, 2024 · 82 likes · 19 shares · 35,775 followers View post →
Un citoyen vigilant
@UnCitoyen1986 · X

@CoralieBorel @Acermendax Et ça, ça vaut rien ? https://t.co/98Klsy82GR

Nov 7, 2022 · 32 followers View post →
Antonio Rubio
@ARubioCampana · X

RT @xiskya: La guerra tiene efectos Intergeneracionales. No solo por el relato verbal de lo sucedido. Las guerrearás impactan sobre las cap…

May 3, 2022 · 5 shares · 12,358 followers View post →
Telbi Falcón
@telbifalcon · X

RT @xiskya: La guerra tiene efectos Intergeneracionales. No solo por el relato verbal de lo sucedido. Las guerrearás impactan sobre las cap…

May 2, 2022 · 5 shares · 100 followers View post →
L i l i
@lilisegunda · X

RT @xiskya: La guerra tiene efectos Intergeneracionales. No solo por el relato verbal de lo sucedido. Las guerrearás impactan sobre las cap…

May 2, 2022 · 5 shares · 428 followers View post →
Xiskya ن
@xiskya · X

La guerra tiene efectos Intergeneracionales. No solo por el relato verbal de lo sucedido. Las guerrearás impactan sobre las capas químicas de los cromosomas, transmitiendo el dolor a través de la memoria biológica. Afectan al gen FKBP5. Fuente del estudio: https://t.co/dK08BtnEdu https://t.co/dfYYsGFBmU

May 2, 2022 · 9 likes · 5 shares · 77,933 followers View post →
Robert McDougal
@robertbmcdougal · X

@primalpoly @vgman94 @Carious1 You should read the book After Meat. As well as the epigenetic studies on Holocaust survivors’ offspring. https://t.co/jlC18aNqUX. https://t.co/DuLR2pds7g

Feb 15, 2022 · 347 followers View post →
9
@victorykn · X

@pancoVilla88 “Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation” https://t.co/4vaJkACLUj

Dec 21, 2021 · 4,219 followers View post →
T.C. Mehmet Özsoylar
@m_ozsoylar · X

https://t.co/eNHdo2RSRW

Sep 2, 2021 · 275 followers View post →
Özlem Tokgöz Özsoylar
@ozlemtokgoz · X

RT @KriterEgitim: Sahip olduğumuz ruhsal sıkıntılar acaba atalarımızdan bize miras olarak aktarılmış olabilir mi? Geçmiş nesilde yaşanan tr…

Sep 1, 2021 · 1 share · 761 followers View post →
Kriter Kurumsal Eğitim ve Danışmanlık
@KriterEgitim · X

Sahip olduğumuz ruhsal sıkıntılar acaba atalarımızdan bize miras olarak aktarılmış olabilir mi? Geçmiş nesilde yaşanan travmatik olayların izleri, nesilden nesile aktarılabilir mi?

Sep 1, 2021 · 2 likes · 1 share · 96 followers View post →
Graham Pechenik
@graham_pechenik · X

@MichaelHaichin @RussellHausfeld @smacdonald10 @JD_Rosenblat FKBP5 is also implicated in intergenerational trauma: Holocaust survivors and their adult offspring have epigenetic changes on the same region of that gene https://t.co/vc08hA4aHG https://t.co/cZAUaOBKny https://t.co/4FuDoFYf5R

Jan 14, 2021 · 2 likes · 5,677 followers View post →
Jasmeet Singh
@PwnzAll · X

Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation https://t.co/crcYf9wSnJ

Jun 3, 2020 · 390 followers View post →
Dr. Courtney "got vaccinated" Wilder
@wilder_courtney · X

@mbbrownlee The journal is Biological Psychiatry; title of the article is Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation; date and link: September 1, 2016; 80:372–380 https://t.co/QU7RQdaqUN Some of the science went over my head but the findings were powerful.

Nov 17, 2019 · 2 likes · 914 followers View post →
DrRPalmquist
@DrPalmquist · X

Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation. - PubMed - NCBI https://t.co/JFWwQV981T

Oct 27, 2019 · 3,159 followers View post →