Publications by authors named "Nikolas Martin"

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Reovirus oncolysis and the next frontiers for this unique oncoviral immunotherapy.
Negar Sharifi, Amir Emamie, Nastaran Rafiee, Salar Pashangzadeh, Eknoor Walia, Nikolas Tim Martin

Semin Immunol· December 2025

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A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection.
Stephen Boulton, Joanna Poutou, Rida Gill, Nouf Alluqmani, Xiaohong He, Nikolas Martin

Mol Ther Methods Clin Dev· December 2023

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Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy.
Nikolas T Martin, Mathieu J F Crupi, Zaid Taha, Joanna Poutou, Jack T Whelan

Pharmaceuticals (Basel)· May 2023

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CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX.
Jack T Whelan, Ragunath Singaravelu, Fuan Wang, Adrian Pelin, Levi A Tamming, Nikolas T Martin

Front Immunol· January 2023

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Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection.
Stephen Boulton, Joanna Poutou, Nikolas T Martin, Taha Azad, Ragunath Singaravelu

Mol Ther· May 2022

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Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry.
Taha Azad, Ragunath Singaravelu, Zaid Taha, Taylor R Jamieson, Stephen Boulton, Nikolas T Martin

Mol Ther· June 2021

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Characterization of Critical Determinants of ACE2-SARS CoV-2 RBD Interaction.
Emily E F Brown, Reza Rezaei, Taylor R Jamieson, Jaahnavi Dave, Nikolas T Martin

Int J Mol Sci· February 2021

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Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization.
Taha Azad, Ragunath Singaravelu, Mathieu J F Crupi, Taylor Jamieson, Jaahnavi Dave, Nikolas T Martin

Membranes (Basel)· August 2020

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A chimeric poxvirus with J2R (thymidine kinase) deletion shows safety and anti-tumor activity in lung cancer models.
Shyambabu Chaurasiya, Nanhai G Chen, Jianming Lu, Nikolas Martin, Yinan Shen

Cancer Gene Ther· April 2020

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Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy.
Julia Niemann, Norman Woller, Jennifer Brooks, Bettina Fleischmann-Mundt, Nikolas T Martin

Nat Commun· July 2019

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Pre-surgical neoadjuvant oncolytic virotherapy confers protection against rechallenge in a murine model of breast cancer.
Nikolas Tim Martin, Dominic Guy Roy, Samuel Tekeste Workenhe, Diana J M van den Wollenberg, Rob C Hoeben

Sci Rep· February 2019

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Oncolytic Virus Combination Therapy: Killing One Bird with Two Stones.
Nikolas Tim Martin, John Cameron Bell

Mol Ther· June 2018

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Brief Communication; A Heterologous Oncolytic Bacteria-Virus Prime-Boost Approach for Anticancer Vaccination in Mice.
Amelia S Aitken, Dominic G Roy, Nikolas T Martin, Subash Sad, John C Bell

J Immunother· April 2018

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Targeting polysialic acid-abundant cancers using oncolytic adenoviruses with fibers fused to active bacteriophage borne endosialidase.
Nikolas T Martin, Christoph Wrede, Julia Niemann, Jennifer Brooks, David Schwarzer

Biomaterials· March 2018

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Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy.
Marie-Claude Bourgeois-Daigneault, Dominic Guy Roy, Amelia Sadie Aitken, Nader El Sayes, Nikolas Tim Martin

Sci Transl Med· January 2018

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Interleukin 33 is a guardian of barriers and a local alarmin.
Nikolas T Martin, Michael U Martin

Nat Immunol· February 2016

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PolySia-Specific Retargeting of Oncolytic Viruses Triggers Tumor-Specific Immune Responses and Facilitates Therapy of Disseminated Lung Cancer.
Arnold Kloos, Norman Woller, Engin Gürlevik, Cristina-Ileana Ureche, Julia Niemann, Nikolas T Martin

Cancer Immunol Res· July 2015

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