Publications by authors named "Nils Pfaff"

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Discovery of BAY 3389934 Hydrochloride: A Potent and Selective Small-Molecule Dual Factor IIa/Xa Inhibitor with Short Half-Life for the Acute Treatment of Sepsis-Induced Coagulopathy.
Hartmut Beck, Stefanie Mesch, Stefanie Zimmermann, Alexandros Vakalopoulos, Lutz Lehmann, Nils Pfaff

J Med Chem· June 2025

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An in vitro pharmacodynamic spiking study of befovacimab, a tissue factor pathway inhibitor monoclonal antibody, in blood samples from patients with severe FVIII deficiency.
Erika J Martin, Melinda E Nolte, Janice Kuhn, Nicole Schmidt, Nils Pfaff

Haemophilia· July 2021

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Inhibition of miRNA-212/132 improves the reprogramming of fibroblasts into induced pluripotent stem cells by de-repressing important epigenetic remodelling factors.
Nils Pfaff, Steffi Liebhaber, Selina Möbus, Abbas Beh-Pajooh, Jan Fiedler

Stem Cell Res· April 2017

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Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy.
Mania Ackermann, Nico Lachmann, Susann Hartung, Reto Eggenschwiler, Nils Pfaff

Biomaterials· February 2014

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Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis.
Nico Lachmann, Christine Happle, Mania Ackermann, Doreen Lüttge, Martin Wetzke, Nils Pfaff

Am J Respir Crit Care Med· January 2014

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MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses.
Ingo Volkmann, Regalla Kumarswamy, Nils Pfaff, Jan Fiedler, Seema Dangwal

Circ Res· September 2013

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From skin to blood: a new member joins the iClub.
Nils Pfaff, Tobias Cantz

Cell Stem Cell· August 2013

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A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny.
Nils Pfaff, Nico Lachmann, Mania Ackermann, Saskia Kohlscheen, Christian Brendel

Stem Cells· March 2013

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miRNAs involved in the generation, maintenance, and differentiation of pluripotent cells.
Nils Pfaff, Thomas Moritz, Thomas Thum, Tobias Cantz

J Mol Med (Berl)· July 2012

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Efficient hematopoietic redifferentiation of induced pluripotent stem cells derived from primitive murine bone marrow cells.
Nils Pfaff, Nico Lachmann, Saskia Kohlscheen, Malte Sgodda, Marcos J Araúzo-Bravo

Stem Cells Dev· March 2012

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miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2.
Nils Pfaff, Jan Fiedler, Angelika Holzmann, Axel Schambach, Thomas Moritz

EMBO Rep· October 2011

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Localisation of gluconeogenesis and tricarboxylic acid (TCA)-cycle enzymes and first functional analysis of the TCA cycle in Toxoplasma gondii.
Tobias Fleige, Nils Pfaff, Uwe Gross, Wolfgang Bohne

Int J Parasitol· August 2008

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