Publications by authors named "Nitin Roper"

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Local Ablative Therapy Followed by Osimertinib Rechallenge in Oligoprogressive, EGFR-Mutated NSCLC: A Phase 2 Study.
Azam Ghafoor, Nitin Roper, Chul Kim, Chuong D Hoang, Aparna H Kesarwala

JTO Clin Res Rep· October 2025

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Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification.
Rebecca M Starble, Eric G Sun, Rana Gbyli, Jonathan Radda, Jiuwei Lu, Nitin Roper

Nat Struct Mol Biol· October 2025

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NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING.
Yoo Sun Kim, Barzin Y Nabet, Briana N Cortez, Nai-Yun Sun, Robin Sebastian, Nitin Roper

J Clin Invest· September 2025

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Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma.
Nai-Yun Sun, Suresh Kumar, Yoo Sun Kim, Diana Varghese, Arnulfo Mendoza, Nitin Roper

Nat Commun· July 2025

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Bimodal Genomic Approach Predicting Semaphorin 7A (SEMA7A) as Prognostic Biomarker in Adrenocortical Carcinoma.
Anjali Dhall, Daiki Taniyama, Fathi Elloumi, Augustin Luna, Sudhir Varma, Nitin Roper

Cancers (Basel)· June 2025

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Bimodal genomic approach predicting Semaphorin 7A (SEMA7A) as prognostic biomarker in adrenocortical carcinoma.
Anjali Dhall, Daiki Taniyama, Fathi Elloumi, Augustin Luna, Sudhir Varma, Nitin Roper

bioRxiv· April 2025

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Epigenetic priming promotes acquisition of tyrosine kinase inhibitor resistance and oncogene amplification in human lung cancer.
Rebecca M Starble, Eric G Sun, Rana Gbyli, Jonathan Radda, Jiuwei Lu, Nitin Roper

bioRxiv· January 2025

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Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma.
Nai-Yun Sun, Suresh Kumar, Yoo Sun Kim, Diana Varghese, Arnulfo Mendoza, Nitin Roper

bioRxiv· October 2024

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A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma Cell Lines, PDX, and Patient Samples.
Yasuhiro Arakawa, Fathi Elloumi, Sudhir Varma, Prashant Khandagale, Ukhyun Jo, Nitin Roper

Cancer Res Commun· September 2024

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Staufen1 Represses the FOXA1-Regulated Transcriptome by Destabilizing FOXA1 mRNA in Colorectal Cancer Cells.
Katherine R Pasterczyk, Xiao Ling Li, Ragini Singh, Meira S Zibitt, Corrine Corrina R Hartford, Nitin Roper

Mol Cell Biol· March 2024

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Author Correction: ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer.
Christopher W Schultz, Yang Zhang, Rajaa Elmeskini, Astrid Zimmermann, Haiqing Fu, Nitin Roper

EMBO Mol Med· March 2024

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Activity of the Ubiquitin-activating Enzyme Inhibitor TAK-243 in Adrenocortical Carcinoma Cell Lines, Patient-derived Organoids, and Murine Xenografts.
Yasuhiro Arakawa, Ukhyun Jo, Suresh Kumar, Nai-Yun Sun, Fathi Elloumi, Nitin Roper

Cancer Res Commun· March 2024

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Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib-resistant EGFR-driven Lung Cancer.
Nitin Roper, Rajaa El Meskini, Tapan Maity, Devon Atkinson, Amanda Day

Cancer Res Commun· February 2024

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The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
Deborah R Caswell, Philippe Gui, Manasi K Mayekar, Emily K Law, Oriol Pich, Nitin Roper

Nat Genet· January 2024

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ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer.
Christopher W Schultz, Yang Zhang, Rajaa Elmeskini, Astrid Zimmermann, Haiqing Fu, Nitin Roper

EMBO Mol Med· August 2023

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Exploration of HER2 (ERBB2) immunohistochemistry in non-small cell lung cancer: correlation with ERBB2 mutational status: experimental research.
Anthony B Cardillo, Sierra Kovar, Nitin Roper, David G Hicks, Moises J Velez

Ann Med Surg (Lond)· June 2023

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Preclinical Models of Adrenocortical Cancer.
Andrew J H Sedlack, Samual J Hatfield, Suresh Kumar, Yasuhiro Arakawa, Nitin Roper

Cancers (Basel)· May 2023

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Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes.
Lőrinc Sándor Pongor, Christopher W Schultz, Lorenzo Rinaldi, Darawalee Wangsa, Christophe E Redon, Nitin Roper

Cancer Discov· April 2023

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Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation.
Lorinc S Pongor, Camille Tlemsani, Fathi Elloumi, Yasuhiro Arakawa, Ukhyun Jo, Nitin Roper

iScience· November 2022

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Preclinical Models of Neuroendocrine Neoplasia.
Andrew J H Sedlack, Kimia Saleh-Anaraki, Suresh Kumar, Po Hien Ear, Kate E Lines, Nitin Roper

Cancers (Basel)· November 2022

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Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models.
Delphine Lissa, Nobuyuki Takahashi, Parth Desai, Irena Manukyan, Christopher W Schultz, Nitin Roper

Nat Commun· April 2022

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Parathyroid Carcinoma: Incidence, Survival Analysis, and Management: A Study from the SEER Database and Insights into Future Therapeutic Perspectives.
Asad Ullah, Jaffar Khan, Abdul Waheed, Nitasha Sharma, Elizabeth K Pryor, Nitin Roper

Cancers (Basel)· March 2022

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New Insights on the Genetics of Pheochromocytoma and Paraganglioma and Its Clinical Implications.
Sakshi Jhawar, Yasuhiro Arakawa, Suresh Kumar, Diana Varghese, Yoo Sun Kim, Nitin Roper

Cancers (Basel)· January 2022

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Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis.
Kosuke Tanaka, Helena A Yu, Shaoyuan Yang, Song Han, S Duygu Selcuklu, Nitin Roper

Cancer Cell· September 2021

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