Publications by authors named "Nobito Higuchi"

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Factors Contributing to the Prognosis after Second-line Therapy with Ramucirumab in Advanced Hepatocellular Carcinoma.
Rie Sugimoto, Kenta Motomura, Aritsune Ooho, Yoshifusa Aratake, Akihiro Ueda, Nobito Higuchi

Intern Med· November 2022

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Atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma progressing after molecular targeted therapy: A multicenter prospective observational study.
Rie Sugimoto, Takeaki Satoh, Akihiro Ueda, Takeshi Senju, Yuki Tanaka, Nobito Higuchi

Medicine (Baltimore)· October 2022

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Direct-acting antiviral agents do not increase the incidence of hepatocellular carcinoma development: a prospective, multicenter study.
Tatsuya Ide, Hironori Koga, Masahito Nakano, Satoru Hashimoto, Hiroshi Yatsuhashi, Nobito Higuchi

Hepatol Int· May 2019

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Predictors of hepatocellular carcinoma recurrence associated with the use of direct-acting antiviral agent therapy for hepatitis C virus after curative treatment: A prospective multicenter cohort study.
Masahito Nakano, Hironori Koga, Tatsuya Ide, Ryoko Kuromatsu, Satoru Hashimoto, Nobito Higuchi

Cancer Med· May 2019

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Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease.
Nobito Higuchi, Masaki Kato, Masatake Tanaka, Masayuki Miyazaki, Shinichiro Takao

Exp Ther Med· November 2011

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[A case of hepatocellular carcinoma with respiratory failure caused by widespread tumor microemboli].
Kosuke Tanaka, Akio Nakasya, Masanori Miyazaki, Shinichiro Takao, Nobito Higuchi

Fukuoka Igaku Zasshi· October 2011

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Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease.
Nobito Higuchi, Masaki Kato, Yuki Shundo, Hirotaka Tajiri, Masatake Tanaka

Hepatol Res· July 2011

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Potential role of branched-chain amino acids in glucose metabolism through the accelerated induction of the glucose-sensing apparatus in the liver.
Nobito Higuchi, Masaki Kato, Masayuki Miyazaki, Masatake Tanaka, Motoyuki Kohjima

J Cell Biochem· January 2011

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Changes in the expression of cholesterol metabolism-associated genes in HCV-infected liver: a novel target for therapy?
Makoto Nakamuta, Ryoko Yada, Tatsuya Fujino, Masayoshi Yada, Nobito Higuchi

Int J Mol Med· December 2009

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The effects of unsaturated fatty acids on lipid metabolism in HepG2 cells.
Motoyuki Kohjima, Munechika Enjoji, Nobito Higuchi, Masaki Kato, Kazuhiro Kotoh

In Vitro Cell Dev Biol Anim· October 2009

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The state of cholesterol metabolism in the liver of patients with primary biliary cirrhosis: the role of MDR3 expression.
Munechika Enjoji, Ryoko Yada, Tatsuya Fujino, Tsuyoshi Yoshimoto, Masayoshi Yada, Nobito Higuchi

Hepatol Int· September 2009

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Impact of cholesterol metabolism and the LXRalpha-SREBP-1c pathway on nonalcoholic fatty liver disease.
Makoto Nakamuta, Tatsuya Fujino, Ryoko Yada, Masayoshi Yada, Kenichiro Yasutake, Nobito Higuchi

Int J Mol Med· May 2009

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The significance of differences in fatty acid metabolism between obese and non-obese patients with non-alcoholic fatty liver disease.
Makoto Nakamuta, Motoyuki Kohjima, Nobito Higuchi, Masaki Kato, Kazuhiro Kotoh

Int J Mol Med· November 2008

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Therapeutic effect of ARBs on insulin resistance and liver injury in patients with NAFLD and chronic hepatitis C: a pilot study.
Munechika Enjoji, Kazuhiro Kotoh, Masaki Kato, Nobito Higuchi, Motoyuki Kohjima

Int J Mol Med· October 2008

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Reduced hepatic expression of adipose tissue triglyceride lipase and CGI-58 may contribute to the development of non-alcoholic fatty liver disease in patients with insulin resistance.
Masaki Kato, Nobito Higuchi, Munechika Enjoji

Scand J Gastroenterol· August 2008

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SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease.
Motoyuki Kohjima, Nobito Higuchi, Masaki Kato, Kazuhiro Kotoh, Tsuyoshi Yoshimoto

Int J Mol Med· April 2008

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Investigation of hyperuricemia during pegylated-interferon-alpha2b plus ribavirin combination therapy in patients with chronic hepatitis C.
Naoki Yamashita, Munechika Enjoji, Kazuhiro Kotoh, Masaki Kato, Akihiro Ueda, Nobito Higuchi

J Dig Dis· February 2008

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Methylprednisolone injection via the portal vein suppresses inflammation in acute liver failure induced in rats by lipopolysaccharide and d-galactosamine.
Nobito Higuchi, Masaki Kato, Kazuhiro Kotoh, Motoyuki Kohjima, Shinichi Aishima

Liver Int· December 2007

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NIM811, a nonimmunosuppressive cyclosporine analogue, suppresses collagen production and enhances collagenase activity in hepatic stellate cells.
Motoyuki Kohjima, Munechika Enjoji, Nobito Higuchi, Kazuhiro Kotoh, Masaki Kato

Liver Int· November 2007

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Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease.
Motoyuki Kohjima, Munechika Enjoji, Nobito Higuchi, Masaki Kato, Kazuhiro Kotoh

Int J Mol Med· September 2007

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