Publications by authors named "Noboru Hiroi"

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Septin5 deficiency impairs both recent and remote contextual fear memory.
Natsumi Ageta-Ishihara, Naoto Fukumasu, Kodai Sakakibara, Kazuki Fujii, Yumie Koshidaka, Noboru Hiroi

Mol Brain· November 2025

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Highly demarcated structural alterations in the brain and impaired social incentive learning in Tbx1 heterozygous mice.
Takeshi Hiramoto, Akira Sumiyoshi, Risa Kato, Takahira Yamauchi, Takeshi Takano, Yukiko J Hiroi, Hiroi Nonaka, Noboru Hiroi

Mol Psychiatry· May 2025

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Meta-analyses of epigenetic age acceleration and GrimAge components of schizophrenia or first-episode psychosis.
Toshiyuki Shirai, Satoshi Okazaki, Takaki Tanifuji, Shusuke Numata, Tomohiko Nakayama, Noboru Hiroi

Schizophrenia (Heidelb)· November 2024

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Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior.
Takashi Komori, Kazuya Okamura, Minobu Ikehara, Kazuhiko Yamamuro, Nozomi Endo, Noboru Hiroi

Mol Psychiatry· May 2024

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Structural alterations in the amygdala and impaired social incentive learning in a mouse model of a genetic variant associated with neurodevelopmental disorders.
Takeshi Hiramoto, Akira Sumiyoshi, Risa Kato, Takahira Yamauchi, Gina Kang, Hiroi Nonaka, Yukiko J Hiroi, Noboru Hiroi

bioRxiv· August 2023

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Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior.
Manabu Makinodan, Takashi Komori, Kazuya Okamura, Minobu Ikehara, Kazuhiko Yamamuro, Noboru Hiroi

Res Sq· June 2023

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Structural alterations in the amygdala and impaired social incentive learning in a mouse model of a genetic variant associated with neurodevelopmental disorders.
Takeshi Hiramoto, Akira Sumiyoshi, Risa Kato, Takahira Yamauchi, Gina Kang, Hiroi Nonaka, Noboru Hiroi

Res Sq· June 2023

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Advanced paternal age diversifies individual trajectories of vocalization patterns in neonatal mice.
Lingling Mai, Hitoshi Inada, Ryuichi Kimura, Kouta Kanno, Takeru Matsuda, Noboru Hiroi

iScience· August 2022

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Tbx1, a gene encoded in 22q11.2 copy number variant, is a link between alterations in fimbria myelination and cognitive speed in mice.
Takeshi Hiramoto, Akira Sumiyoshi, Takahira Yamauchi, Kenji Tanigaki, Qian Shi, Hiroi Nonaka, Noboru Hiroi

Mol Psychiatry· February 2022

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Computational identification of variables in neonatal vocalizations predictive for postpubertal social behaviors in a mouse model of 16p11.2 deletion.
Mitsuteru Nakamura, Kenny Ye, Mariel Barbachan E Silva, Takahira Yamauchi, Daniel J Hoeppner, Noboru Hiroi

Mol Psychiatry· November 2021

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Heterozygosity of murine Crkl does not recapitulate behavioral dimensions of human 22q11.2 hemizygosity.
Takahira Yamauchi, Gina Kang, Noboru Hiroi

Genes Brain Behav· June 2021

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Maternal approach behaviors toward neonatal calls are impaired by mother's experiences of raising pups with a risk gene variant for autism.
Risa Kato, Akihiro Machida, Kensaku Nomoto, Gina Kang, Takeshi Hiramoto, Noboru Hiroi

Dev Psychobiol· January 2021

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Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ.
Mikael Marttinen, Catarina B Ferreira, Kaisa M A Paldanius, Mari Takalo, Teemu Natunen, Noboru Hiroi

Cells· November 2020

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Neurobiological perspective of 22q11.2 deletion syndrome.
Janneke R Zinkstok, Erik Boot, Anne S Bassett, Noboru Hiroi, Nancy J Butcher

Lancet Psychiatry· November 2019

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Modeling and Predicting Developmental Trajectories of Neuropsychiatric Dimensions Associated With Copy Number Variations.
Noboru Hiroi, Takahira Yamauchi

Int J Neuropsychopharmacol· August 2019

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Computational Analysis of Neonatal Mouse Ultrasonic Vocalization.
Pilib Ó Broin, Michael V Beckert, Tomohisa Takahashi, Takeshi Izumi, Kenny Ye, Noboru Hiroi

Curr Protoc Mouse Biol· June 2018

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Critical reappraisal of mechanistic links of copy number variants to dimensional constructs of neuropsychiatric disorders in mouse models.
Noboru Hiroi

Psychiatry Clin Neurosci· May 2018

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Human COMT over-expression confers a heightened susceptibility to dyskinesia in mice.
Oscar Solís, Jose-Rubén García-Montes, Patricia Garcia-Sanz, Antonio S Herranz, Maria-José Asensio, Noboru Hiroi

Neurobiol Dis· June 2017

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Cry, baby, cry: Expression of Distress as a Biomarker and Modulator in Autism Spectrum Disorder.
Gianluca Esposito, Noboru Hiroi, Maria Luisa Scattoni

Int J Neuropsychopharmacol· February 2017

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A Self-Generated Environmental Factor as a Potential Contributor to Atypical Early Social Communication in Autism.
Takefumi Kikusui, Noboru Hiroi

Neuropsychopharmacology· January 2017

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Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research.
John H Krystal, Anissa Abi-Dargham, Schahram Akbarian, Amy F T Arnsten, Deanna M Barch, Noboru Hiroi

Biol Psychiatry· July 2016

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Molecular Histochemistry Identifies Peptidomic Organization and Reorganization Along Striatal Projection Units.
Akitoyo Hishimoto, Hiroko Nomaru, Kenny Ye, Akira Nishi, Jihyeon Lim, Noboru Hiroi

Biol Psychiatry· March 2016

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Neonatal maternal separation alters the capacity of adult neural precursor cells to differentiate into neurons via methylation of retinoic acid receptor gene promoter.
Shuken Boku, Hiroyuki Toda, Shin Nakagawa, Akiko Kato, Takeshi Inoue, Noboru Hiroi

Biol Psychiatry· February 2015

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Small cracks in the dam: rare genetic variants provide opportunities to delve into mechanisms of neuropsychiatric disorders.
Noboru Hiroi

Biol Psychiatry· July 2014

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Alterations of social interaction through genetic and environmental manipulation of the 22q11.2 gene Sept5 in the mouse brain.
Kathryn M Harper, Takeshi Hiramoto, Kenji Tanigaki, Gina Kang, Go Suzuki, Noboru Hiroi

Hum Mol Genet· August 2012

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