Publications by authors named "Noboru Sakabe"

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Shared loci but distinct variants underlie genetic architecture of allergic diseases.
Isabella M Salamone, Xiaoyuan Zhong, Noboru J Sakabe, Robert Mitchell, William Wentworth-Sheilds

medRxiv· June 2025

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Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations.
Xiaoyuan Zhong, Robert Mitchell, Christine Billstrand, Emma E Thompson, Noboru J Sakabe

Genome Med· April 2025

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Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations.
Xiaoyuan Zhong, Robert Mitchell, Christine Billstrand, Emma Thompson, Noboru J Sakabe

medRxiv· February 2025

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Mechanosensitive super-enhancers regulate genes linked to atherosclerosis in endothelial cells.
Jin Li, Jiayu Zhu, Olivia Gray, Débora R Sobreira, David Wu, Noboru J Sakabe

J Cell Biol· March 2024

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Single cell profiling at the maternal-fetal interface reveals a deficiency of PD-L1 non-immune cells in human spontaneous preterm labor.
Xiao Liu, Ivy Aneas, Noboru Sakabe, Rebecca L Anderson, Christine Billstrand

Sci Rep· May 2023

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Genetics of sexually dimorphic adipose distribution in humans.
Grace T Hansen, Débora R Sobreira, Zachary T Weber, Alexis G Thornburg, Ivy Aneas, Noboru J Sakabe

Nat Genet· March 2023

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A pleiotropic hypoxia-sensitive enhancer is disrupted by adaptive alleles in Tibetans.
Olivia A Gray, Jennifer Yoo, Débora R Sobreira, Jordan Jousma, David Witonsky, Noboru J Sakabe

Sci Adv· November 2022

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Establishment of human induced trophoblast stem-like cells from term villous cytotrophoblasts.
Tao Bai, Chian-Yu Peng, Ivy Aneas, Noboru Sakabe, Daniela F Requena

Stem Cell Res· October 2021

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Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region.
Ivy Aneas, Donna C Decker, Chanie L Howard, Débora R Sobreira, Noboru J Sakabe

Nat Commun· October 2021

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A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci.
Amelia C Joslin, Débora R Sobreira, Grace T Hansen, Noboru J Sakabe, Ivy Aneas

Nat Commun· September 2021

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Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of and .
Débora R Sobreira, Amelia C Joslin, Qi Zhang, Iain Williamson, Grace T Hansen, Noboru J Sakabe

Science· June 2021

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Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua.
Virginia Chu Cheung, Chian-Yu Peng, Mirna Marinić, Noboru J Sakabe, Ivy Aneas

Cell Rep· May 2021

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Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth.
Noboru J Sakabe, Ivy Aneas, Nicholas Knoblauch, Debora R Sobreira, Nicole Clark

Sci Adv· December 2020

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Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma.
Britney A Helling, Débora R Sobreira, Grace T Hansen, Noboru J Sakabe, Kaixuan Luo

Commun Biol· November 2020

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A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.
Laila El Khattabi, Haiyan Zhao, Jens Kalchschmidt, Natalie Young, Seolkyoung Jung, Noboru Sakabe

Cell· August 2019

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Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial Development.
Cornelis J Boogerd, Xiaoming Zhu, Ivy Aneas, Noboru Sakabe, Lunfeng Zhang

Circ Res· August 2018

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A promoter interaction map for cardiovascular disease genetics.
Lindsey E Montefiori, Debora R Sobreira, Noboru J Sakabe, Ivy Aneas, Amelia C Joslin

Elife· July 2018

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Probing chromatin landscape reveals roles of endocardial TBX20 in septation.
Cornelis J Boogerd, Ivy Aneas, Noboru Sakabe, Ralph J Dirschinger, Quen J Cheng

J Clin Invest· August 2016

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HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes.
Nuno Guimarães-Camboa, Jennifer Stowe, Ivy Aneas, Noboru Sakabe, Paola Cattaneo

Dev Cell· June 2015

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Obesity-associated variants within FTO form long-range functional connections with IRX3.
Scott Smemo, Juan J Tena, Kyoung-Han Kim, Eric R Gamazon, Noboru J Sakabe

Nature· March 2014

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Beyond the ENCODE project: using genomics and epigenomics strategies to study enhancer evolution.
Noboru Jo Sakabe, Marcelo A Nobrega

Philos Trans R Soc Lond B Biol Sci· December 2013

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Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function.
Noboru J Sakabe, Ivy Aneas, Tao Shen, Leila Shokri, Soo-Young Park

Hum Mol Genet· May 2012

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Transcriptional enhancers in development and disease.
Noboru Jo Sakabe, Daniel Savic, Marcelo A Nobrega

Genome Biol· January 2012

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Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function.
Tao Shen, Ivy Aneas, Noboru Sakabe, Ralf J Dirschinger, Gang Wang

J Clin Invest· December 2011

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Genome-wide maps of transcription regulatory elements.
Noboru J Sakabe, Marcelo A Nobrega

Wiley Interdiscip Rev Syst Biol Med· December 2010

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